ENSMUSG00000027999


Mus musculus

Features
Gene ID: ENSMUSG00000027999
  
Biological name :Pla2g12a
  
Synonyms : Group XIIA secretory phospholipase A2 / Pla2g12a / Q9EPR2
  
Possible biological names infered from orthology : phospholipase A2 group XIIA / Q9BZM1
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: G3
Gene start: 129878606
Gene end: 129895825
  
Corresponding Affymetrix probe sets: 10496015 (MoGene1.0st)   1452026_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029629
Ensembl peptide - ENSMUSP00000053651
Ensembl peptide - ENSMUSP00000143771
NCBI entrez gene - 66350     See in Manteia.
MGI - MGI:1913600
RefSeq - NM_001286948
RefSeq - NM_023196
RefSeq - NM_183423
RefSeq Peptide - NP_001273877
RefSeq Peptide - NP_075685
RefSeq Peptide - NP_904359
swissprot - Q9EPR2
swissprot - A0A0G2JH03
Ensembl - ENSMUSG00000027999
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pla2g12aENSDARG00000070454Danio rerio
 PLA2G12AENSGALG00000012185Gallus gallus
 Q9BZM1ENSG00000123739Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pla2g12b / phospholipase A2 group XIIB / Q9BX93*ENSMUSG0000000964641


Protein motifs (from Interpro)
Interpro ID Name
 IPR010711  Group XII secretory phospholipase A2 precursor
 IPR033113  Phospholipase A2, histidine active site
 IPR036444  Phospholipase A2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006644 phospholipid metabolic process IEA
 biological_processGO:0016042 lipid catabolic process IC
 biological_processGO:0050482 arachidonic acid secretion IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 molecular_functionGO:0004623 phospholipase A2 activity IDA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0102567 phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) IEA
 molecular_functionGO:0102568 phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) IEA


Pathways (from Reactome)
Pathway description
Acyl chain remodelling of PC
Acyl chain remodelling of PS
Acyl chain remodelling of PE
Acyl chain remodelling of PI
Acyl chain remodelling of PG
Synthesis of PA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr