ENSMUSG00000028133


Mus musculus

Features
Gene ID: ENSMUSG00000028133
  
Biological name :Rwdd3
  
Synonyms : Rwdd3 / RWD domain containing 3
  
Possible biological names infered from orthology : Q9Y3V2
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: G1
Gene start: 121155398
Gene end: 121171695
  
Corresponding Affymetrix probe sets: 10501795 (MoGene1.0st)   1420732_at (Mouse Genome 430 2.0 Array)   1430167_a_at (Mouse Genome 430 2.0 Array)   1451809_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000102075
Ensembl peptide - ENSMUSP00000133036
Ensembl peptide - ENSMUSP00000130734
Ensembl peptide - ENSMUSP00000129262
Ensembl peptide - ENSMUSP00000040826
Ensembl peptide - ENSMUSP00000102074
NCBI entrez gene - 66568     See in Manteia.
MGI - MGI:1920420
RefSeq - XM_011240196
RefSeq - NM_025637
RefSeq - NM_028456
RefSeq - XM_011240195
RefSeq Peptide - NP_082732
RefSeq Peptide - NP_079913
swissprot - E9PZT2
swissprot - Q3UYX7
swissprot - E9PVR5
swissprot - F7AYC4
swissprot - E9Q1R6
Ensembl - ENSMUSG00000028133
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RWDD3ENSGALG00000038421Gallus gallus
 RWDD3ENSG00000122481Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006575  RWD domain
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0033235 positive regulation of protein sumoylation IEA
 biological_processGO:1902073 positive regulation of hypoxia-inducible factor-1alpha signaling pathway IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
SUMO is transferred from E1 to E2 (UBE2I, UBC9)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000565 oligodactyly "congenital condition in which some digits or parts of digits are missing" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
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Allelic Composition: Rsad1tm1.1(KOMP)Vlcg/Rsad1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Rsad1tm1.1(KOMP)Vlcg/Ucd

 MP:0003233 prolonged QT interval "increase in the length of time required for ventricular depolarization and repolarization to occur, usually as a result of increased repolarization time" [J:93197, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Rsad1tm1.1(KOMP)Vlcg/Rsad1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Rsad1tm1.1(KOMP)Vlcg/Ucd

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rsad1tm1.1(KOMP)Vlcg/Rsad1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Rsad1tm1.1(KOMP)Vlcg/Ucd

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Rsad1tm1.1(KOMP)Vlcg/Rsad1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Rsad1tm1.1(KOMP)Vlcg/Ucd

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Rsad1tm1.1(KOMP)Vlcg/Rsad1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Rsad1tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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