ENSMUSG00000028976


Mus musculus

Features
Gene ID: ENSMUSG00000028976
  
Biological name :Slc2a5
  
Synonyms : Q9WV38 / Slc2a5 / solute carrier family 2 (facilitated glucose transporter), member 5
  
Possible biological names infered from orthology : P22732 / solute carrier family 2 member 5
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: E2
Gene start: 150119283
Gene end: 150144169
  
Corresponding Affymetrix probe sets: 10510516 (MoGene1.0st)   1416639_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000030826
NCBI entrez gene - 56485     See in Manteia.
MGI - MGI:1928369
RefSeq - XM_017320329
RefSeq - NM_019741
RefSeq - XM_006539076
RefSeq Peptide - NP_062715
swissprot - Q9WV38
Ensembl - ENSMUSG00000028976
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc2a5ENSDARG00000077875Danio rerio
 ENSGALG00000002466Gallus gallus
 P22732ENSG00000142583Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Slc2a7 / solute carrier family 2 (facilitated glucose transporter), member 7 / Q6PXP3* / solute carrier family 2 member 7*ENSMUSG0000006206456
Slc2a9 / solute carrier family 2 (facilitated glucose transporter), member 9 / Q9NRM0* / solute carrier family 2 member 9*ENSMUSG0000000510745
P32037 / Slc2a3 / solute carrier family 2 (facilitated glucose transporter), member 3 / P11169* / Q8TDB8* / SLC2A14* / solute carrier family 2 member 3* / solute carrier family 2 member 14*ENSMUSG0000000315341
P17809 / Slc2a1 / solute carrier family 2 (facilitated glucose transporter), member 1 / P11166* / solute carrier family 2 member 1*ENSMUSG0000002864541
P14142 / Slc2a4 / solute carrier family 2 (facilitated glucose transporter), member 4 / P14672* / solute carrier family 2 member 4*ENSMUSG0000001856640
P14246 / Slc2a2 / solute carrier family 2 (facilitated glucose transporter), member 2 / P11168* / solute carrier family 2 member 2*ENSMUSG0000002769038


Protein motifs (from Interpro)
Interpro ID Name
 IPR002442  Fructose transporter, type 5 (GLUT5)
 IPR003663  Sugar/inositol transporter
 IPR005828  Major facilitator, sugar transporter-like
 IPR005829  Sugar transporter, conserved site
 IPR020846  Major facilitator superfamily domain
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal IMP
 biological_processGO:0008643 carbohydrate transport IEA
 biological_processGO:0009750 response to fructose IMP
 biological_processGO:0015755 fructose transmembrane transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071332 cellular response to fructose stimulus IDA
 biological_processGO:1990539 fructose import across plasma membrane IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0042383 sarcolemma ISS
 molecular_functionGO:0005215 transporter activity IEA
 molecular_functionGO:0005353 fructose transmembrane transporter activity IMP
 molecular_functionGO:0022857 transmembrane transporter activity IEA
 molecular_functionGO:0070061 fructose binding ISS


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Intestinal hexose absorption


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001303 abnormal lens morphology "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
Show

Allelic Composition: Slc24a5tm1b(KOMP)Mbp/Slc24a5tm1b(KOMP)Mbp
Genetic Background: C57BL/6N-Slc24a5tm1b(KOMP)Mbp/J

 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Slc24a5tm1b(KOMP)Mbp/Slc24a5tm1b(KOMP)Mbp
Genetic Background: C57BL/6N-Slc24a5tm1b(KOMP)Mbp/J

 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
Show

Allelic Composition: Slc24a5tm1b(KOMP)Mbp/Slc24a5tm1b(KOMP)Mbp
Genetic Background: C57BL/6N-Slc24a5tm1b(KOMP)Mbp/J

 MP:0010052 increased grip strength "greater ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Slc24a5tm1b(KOMP)Mbp/Slc24a5tm1b(KOMP)Mbp
Genetic Background: C57BL/6N-Slc24a5tm1b(KOMP)Mbp/J

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Slc24a5tm1b(KOMP)Mbp/Slc24a5tm1b(KOMP)Mbp
Genetic Background: C57BL/6N-Slc24a5tm1b(KOMP)Mbp/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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