ENSMUSG00000029019


Mus musculus

Features
Gene ID: ENSMUSG00000029019
  
Biological name :Nppb
  
Synonyms : natriuretic peptide type B / Nppb / P40753
  
Possible biological names infered from orthology : natriuretic peptide B / P16860
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: E2
Gene start: 147985788
Gene end: 147987205
  
Corresponding Affymetrix probe sets: 10510260 (MoGene1.0st)   1450791_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000099521
NCBI entrez gene - 18158     See in Manteia.
MGI - MGI:97368
RefSeq - NM_008726
RefSeq - NM_001287348
RefSeq Peptide - NP_001274277
RefSeq Peptide - NP_032752
swissprot - P40753
swissprot - Q54AE9
Ensembl - ENSMUSG00000029019
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NPPAENSGALG00000004574Gallus gallus
 NPPBENSG00000120937Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000663  Natriuretic peptide
 IPR002408  Natriuretic peptide, brain type
 IPR030480  Natriuretic peptide, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006182 cGMP biosynthetic process ISS
 biological_processGO:0007168 receptor guanylyl cyclase signaling pathway ISS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0014898 cardiac muscle hypertrophy in response to stress IDA
 biological_processGO:0050880 regulation of blood vessel size IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0005179 hormone activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000278 abnormal myocardial fiber morphology "malformed or poorly developed cardiac muscle fibers, the multinucleated muscle cells of the heart" [J:18048]
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Allelic Composition: Agtpbp1pcd-6J/Agtpbp1pcd-6J
Genetic Background: C57BL/6J-Agtpbp1pcd-6J/J

 MP:0003141 cardiac fibrosis "formation of fibrous tissue within the heart often resulting from inflammation or injury " [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Agtpbp1pcd-6J/Agtpbp1pcd-6J
Genetic Background: C57BL/6J-Agtpbp1pcd-6J/J

 MP:0005294 abnormal heart ventricle morphology "structural anomaly of one or both of the two lower chambers of the heart " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Agtpbp1pcd-6J/Agtpbp1pcd-6J
Genetic Background: C57BL/6J-Agtpbp1pcd-6J/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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