ENSMUSG00000029206


Mus musculus

Features
Gene ID: ENSMUSG00000029206
  
Biological name :Nsun7
  
Synonyms : Nsun7 / Putative methyltransferase NSUN7 / Q14AW5
  
Possible biological names infered from orthology : NOP2/Sun RNA methyltransferase family member 7 / Q8NE18
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: C3.1
Gene start: 66259897
Gene end: 66298026
  
Corresponding Affymetrix probe sets: 10522192 (MoGene1.0st)   1429572_at (Mouse Genome 430 2.0 Array)   1457543_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000144520
Ensembl peptide - ENSMUSP00000031109
Ensembl peptide - ENSMUSP00000144498
NCBI entrez gene - 70918     See in Manteia.
MGI - MGI:1918168
RefSeq - XM_017321098
RefSeq - NM_001302834
RefSeq - NM_027602
RefSeq - XM_006504101
RefSeq - XM_006504102
RefSeq - XM_011240769
RefSeq - XM_011240770
RefSeq - NM_001302833
RefSeq Peptide - NP_081878
RefSeq Peptide - NP_001289762
RefSeq Peptide - NP_001289763
swissprot - E9QPI2
swissprot - Q14AW5
swissprot - A0A0J9YV71
Ensembl - ENSMUSG00000029206
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NSUN7ENSGALG00000014264Gallus gallus
 NSUN7ENSG00000179299Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nsun5 / Q8K4F6 / Probable 28S rRNA (cytosine-C(5))-methyltransferase / Q96P11* / NOP2/Sun RNA methyltransferase family member 5*ENSMUSG0000000091613


Protein motifs (from Interpro)
Interpro ID Name
 IPR001678  SAM-dependent methyltransferase RsmB/NOP2-type
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030317 flagellated sperm motility IMP
 biological_processGO:0030382 sperm mitochondrion organization IMP
 biological_processGO:0032259 methylation IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
Show

Allelic Composition: Catsper3tm1Wyan/Catsper3tm1Wyan
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Catsper3tm1Wyan/Catsper3tm1Wyan
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0002674 abnormal sperm motility "anomalies in the mobility of the spermatozoa" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Catsper3tm1Wyan/Catsper3tm1Wyan
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Nsun7Ste5Jcs1/Nsun7Ste5Jcs1
Genetic Background: involves: C57BL/6

 MP:0009831 abnormal sperm midpiece morphology "any structural abnormality of the highly organized segment of the sperm flagellum which begins at the connecting piece and is characterized by the presence of 9 outer dense fibers (ODFs) that lie outside each of the 9 outer axonemal microtubule doublets and by a sheath of mitochondria that encloses the ODFs and the axoneme; the midpiece terminates about one-fourth of the way down the sperm flagellum at the annulus, which marks the beginning of the principal piece" [PMID:14581499]
Show

Allelic Composition: Nsun7Ste5Jcs1/Nsun7Ste5Jcs1
Genetic Background: involves: C57BL/6

 MP:0009832 abnormal sperm mitochondrial sheath morphology "any structural anomaly or impairment of the tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum" [PMID:14581499]
Show

Allelic Composition: Nsun7Ste5Jcs1/Nsun7Ste5Jcs1
Genetic Background: involves: C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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