ENSMUSG00000029501


Mus musculus

Features
Gene ID: ENSMUSG00000029501
  
Biological name :Ankle2
  
Synonyms : Ankle2 / Ankyrin repeat and LEM domain-containing protein 2 / Q6P1H6
  
Possible biological names infered from orthology : ankyrin repeat and LEM domain containing 2 / Q86XL3
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: F
Gene start: 110231004
Gene end: 110256651
  
Corresponding Affymetrix probe sets: 10524150 (MoGene1.0st)   1429082_at (Mouse Genome 430 2.0 Array)   1434721_at (Mouse Genome 430 2.0 Array)   1453017_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031474
Ensembl peptide - ENSMUSP00000083878
Ensembl peptide - ENSMUSP00000143044
NCBI entrez gene - 71782     See in Manteia.
MGI - MGI:1261856
RefSeq - NM_001253814
RefSeq - NM_027922
RefSeq Peptide - NP_001240743
RefSeq Peptide - NP_082198
swissprot - Q6P1H6
Ensembl - ENSMUSG00000029501
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ankle2ENSDARG00000035607Danio rerio
 ANKLE2ENSGALG00000002143Gallus gallus
 ANKLE2ENSG00000176915Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003887  LEM domain
 IPR011015  LEM/LEM-like domain superfamily
 IPR020683  Ankyrin repeat-containing domain
 IPR035006  Ankyrin repeat and LEM domain-containing protein 2, LEM domain
 IPR035007  Ankyrin repeat and LEM domain-containing protein 2
 IPR036770  Ankyrin repeat-containing domain superfamily
 IPR037056  Ribonuclease H1, N-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007084 mitotic nuclear envelope reassembly ISO
 biological_processGO:0007417 central nervous system development ISS
 biological_processGO:0035307 positive regulation of protein dephosphorylation IBA
 biological_processGO:0042326 negative regulation of phosphorylation IBA
 biological_processGO:0043066 negative regulation of apoptotic process ISS
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane ISS
 molecular_functionGO:0051721 protein phosphatase 2A binding IBA


Pathways (from Reactome)
Pathway description
Initiation of Nuclear Envelope Reformation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000021115 Vrk1 / Q80X41 / vaccinia related kinase 1 / Q99986*  / complex / reaction






 

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contact: otassy@igbmc.fr