ENSMUSG00000029707


Mus musculus
actinFscn3fascinfilamentcellcytoskeletonbindingorganizationactin-crosslinkingdomainmetazoansfascin-establishmentmaintenancepolarityspermatiddevelopmentanatomicalstructuremorphogenesismigrationbundleassemblyrufflecytoplasmmicrovilluslamellipodiumfilopodiumgrowthconeprojection

Features
Gene ID: ENSMUSG00000029707
  
Biological name :Fscn3
  
Synonyms : Fascin-3 / Fscn3 / Q9QXW4
  
Possible biological names infered from orthology : fascin actin-bundling protein 3 / Q9NQT6
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: A3.3
Gene start: 28427789
Gene end: 28438622
  
Corresponding Affymetrix probe sets: 10536752 (MoGene1.0st)   1418948_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031719
NCBI entrez gene - 56223     See in Manteia.
MGI - MGI:1890386
RefSeq - NM_019569
RefSeq - XM_006505141
RefSeq Peptide - NP_062515
swissprot - Q9QXW4
Ensembl - ENSMUSG00000029707
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FSCN3ENSG00000106328Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fscn1 / Q61553 / Fascin / Q16658* / fascin actin-bundling protein 1*ENSMUSG0000002958129
Fscn2 / Q32M02 / Fascin-2 / O14926* / fascin actin-bundling protein 2, retinal*ENSMUSG0000002538027


Protein motifs (from Interpro)
Interpro ID Name
 IPR008999  Actin-crosslinking
 IPR010431  Fascin
 IPR022768  Fascin domain
 IPR024703  Fascin, metazoans
 IPR030143  Fascin-3


Gene Ontology (GO)
cellular component organizationactin filament-based processestablishment or maintenance of cell polarityanatomical structure developmentcellular developmental processmulticellular organism reproductionlocalization of cellmovement of cell or subcellular componentcellular component biogenesiscellular component organizationactin filament-based processestablishment or maintenance of cell polarityanatomical structure developmentcellular developmental processmulticellular organism reproductionlocalization of cellmovement of cell or subcellular componentcellular component biogenesiscellular component organizationactin filament-based processestablishment or maintenance of cell polarityanatomical structure developmentcellular developmental processmulticellular organism reproductionlocalization of cellmovement of cell or subcellular componentcellular component biogenesiscellular component organizationactin filament-based processestablishment or maintenance of cell polarityanatomical structure developmentcellular developmental processmulticellular organism reproductionlocalization of cellmovement of cell or subcellular componentcellular component biogenesiscellular component organizationactin filament-based processestablishment or maintenance of cell polarityanatomical structure developmentcellular developmental processmulticellular organism reproductionlocalization of cellmovement of cell or subcellular componentcellular component biogenesiscellular component organizationactin filament-based processestablishment or maintenance of cell polarityanatomical structure developmentcellular developmental processmulticellular organism reproductionlocalization of cellmovement of cell or subcellular componentcellular component biogenesiscellular component organizationactin filament-based processestablishment or maintenance of cell polarityanatomical structure developmentcellular developmental processmulticellular organism reproductionlocalization of cellmovement of cell or subcellular componentcellular component biogenesiscellular component organizationactin filament-based processestablishment or maintenance of cell polarityanatomical structure developmentcellular developmental processmulticellular organism reproductionlocalization of cellmovement of cell or subcellular componentcellular component biogenesiscellular component organizationactin filament-based processestablishment or maintenance of cell polarityanatomical structure developmentcellular developmental processmulticellular organism reproductionlocalization of cellmovement of cell or subcellular componentcellular component biogenesiscellular component organizationactin filament-based processestablishment or maintenance of cell polarityanatomical structure developmentcellular developmental processmulticellular organism reproductionlocalization of cellmovement of cell or subcellular componentcellular component biogenesiscellular componcellular component organizationactin filament-actin filament-based processestablishment oestablishment or maintenance of cell polarityanatomical struanatomical structure developmentcellular develocellular developmental processmulticellular omulticellular organism reproductionlocalization oflocalization of cellmovement of celmovement of cell or subcellular componentcellular componcellular component biogenesis
protein bindingmolecular adaptor activityprotein-containing complex bindingprotein bindingmolecular adaptor activityprotein-containing complex bindingprotein bindingmolecular adaptor activityprotein-containing complex bindingprotein bindingmolecular adaptor activityprotein-containing complex bindingprotein bindingmolecular adaptor activityprotein-containing complex bindingprotein bindingmolecular adaptor activityprotein-containing complex bindingprotein bindingmolecular adaptor activityprotein-containing complex bindingprotein bindingmolecular adaptor activityprotein-containing complex bindingprotein bindingmolecular adaptor activityprotein-containing complex bindingprotein bindingmolecular adaptor activityprotein-containing complex bindingprotein bindingprotein bindingmolecular adaptor activitymolecular adaptor activityprotein-containing complex bindingprotein-containing complex binding
cellorganellemembraneprotein-containing complexsupramolecular complexcellorganellemembraneprotein-containing complexsupramolecular complexcellorganellemembraneprotein-containing complexsupramolecular complexcellorganellemembraneprotein-containing complexsupramolecular complexcellorganellemembraneprotein-containing complexsupramolecular complexcellorganellemembraneprotein-containing complexsupramolecular complexcellorganellemembraneprotein-containing complexsupramolecular complexcellorganellemembraneprotein-containing complexsupramolecular complexcellorganellemembraneprotein-containing complexsupramolecular complexcellorganellemembraneprotein-containing complexsupramolecular complexcellcellorganelleorganellemembranemembraneprotein-containing complexprotein-containing complexsupramolecular complexsupramolecular complex
TypeGO IDTermEv.Code
 biological_processGO:0007015 actin filament organization IEA
 biological_processGO:0007163 establishment or maintenance of cell polarity IBA
 biological_processGO:0007286 spermatid development TAS
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0016477 cell migration IBA
 biological_processGO:0030036 actin cytoskeleton organization ISS
 biological_processGO:0051017 actin filament bundle assembly IBA
 cellular_componentGO:0001726 ruffle IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005902 microvillus IBA
 cellular_componentGO:0015629 actin cytoskeleton ISS
 cellular_componentGO:0030027 lamellipodium IBA
 cellular_componentGO:0030175 filopodium IBA
 cellular_componentGO:0030426 growth cone IBA
 cellular_componentGO:0031253 cell projection membrane IBA
 cellular_componentGO:0031941 filamentous actin IBA
 molecular_functionGO:0003779 actin binding ISS
 molecular_functionGO:0030674 protein binding, bridging IEA
 molecular_functionGO:0051015 actin filament binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr