ENSMUSG00000029712


Mus musculus

Features
Gene ID: ENSMUSG00000029712
  
Biological name :Actl6b
  
Synonyms : actin-like 6B / Actl6b / Q99MR0
  
Possible biological names infered from orthology : O94805
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: G2
Gene start: 137553517
Gene end: 137569582
  
Corresponding Affymetrix probe sets: 10526614 (MoGene1.0st)   1422564_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000117138
Ensembl peptide - ENSMUSP00000143702
Ensembl peptide - ENSMUSP00000123004
Ensembl peptide - ENSMUSP00000121672
Ensembl peptide - ENSMUSP00000119356
Ensembl peptide - ENSMUSP00000117425
Ensembl peptide - ENSMUSP00000031725
NCBI entrez gene - 83766     See in Manteia.
MGI - MGI:1933548
RefSeq - XM_017321187
RefSeq - XM_006504640
RefSeq - XM_006504639
RefSeq - XM_006504638
RefSeq - XM_006504637
RefSeq - NM_031404
RefSeq - XM_006504635
RefSeq - XM_006504636
RefSeq Peptide - NP_113581
swissprot - Q99MR0
swissprot - D3Z5W4
swissprot - F8WI57
swissprot - A0A0G2JGU5
swissprot - A0A1C7ZN05
swissprot - D3Z2E2
swissprot - D3Z4L2
Ensembl - ENSMUSG00000029712
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 actl6bENSDARG00000034107Danio rerio
 ACTL6BENSG00000077080Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Actl6a / Q9Z2N8 / actin-like 6A / O96019*ENSMUSG0000002767183


Protein motifs (from Interpro)
Interpro ID Name
 IPR004000  Actin family
 IPR004001  Actin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006333 chromatin assembly or disassembly IC
 biological_processGO:0006338 chromatin remodeling IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007399 nervous system development IMP
 biological_processGO:0021510 spinal cord development IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0016514 SWI/SNF complex IEA
 cellular_componentGO:0071565 nBAF complex IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
RMTs methylate histone arginines
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000920 abnormal myelination "atypical or altered myelination in axon sheaths" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ifngtm1Ts/Ifngtm1Ts,Socs1tm1Jni/Socs1tm1Jni
Genetic Background: involves: 129S7/SvEvBrd

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
Show

Allelic Composition: Ifngtm1Ts/Ifngtm1Ts,Socs1tm1Jni/Socs1tm1Jni
Genetic Background: involves: 129S7/SvEvBrd

 MP:0004998 decreased CNS synapse formation "a reduction in the frequency of the process of generating the initial connections between an axon and effector tissue or neuron" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ifngtm1Ts/Ifngtm1Ts,Socs1tm1Jni/Socs1tm1Jni
Genetic Background: involves: 129S7/SvEvBrd

 MP:0008143 abnormal dendrite morphology "any structural anomaly of the highly branched tree-like process of a neuron that serves as a receptive field and conducts impulses toward the cell body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ifngtm1Ts/Ifngtm1Ts,Socs1tm1Jni/Socs1tm1Jni
Genetic Background: involves: 129S7/SvEvBrd

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Ifngtm1Ts/Ifngtm1Ts,Socs1tm1Jni/Socs1tm1Jni
Genetic Background: involves: 129S7/SvEvBrd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr