ENSMUSG00000029833
Mus musculus binding Trim24 zinc regulation finger protein transcription activity phd-type dna-templated conserved site ion bromodomain ring-type fyve proliferation process receptor response estrogen p nuclear dna transferase liver b-box-type b-box c-terminal ring phd-finger
Features Gene ID: ENSMUSG00000029833 Biological name :Trim24 Synonyms : Q64127 / / Possible biological names infered from orthology : O15164 / Species: Mus musculus Chr. number: 6 Strand: 1 Band: B1 Gene start: 37870811 Gene end: 37966296 Corresponding Affymetrix probe sets: 10537318 (MoGene1.0st) 1427258_at (Mouse Genome 430 2.0 Array) 1427259_at (Mouse Genome 430 2.0 Array) 1446295_at (Mouse Genome 430 2.0 Array) Cross references: Ensembl peptide - ENSMUSP0000003185921848
See in Manteia .
MGI:109275 XM_006505895 NM_001272064 NM_001272076 NM_145076 NP_001258993 NP_001259005 NP_659542 Q64127 E9Q1U8 ENSMUSG00000029833
See expression report in BioGPS See gene description in Wikigenes See co-cited genes in PubMed Ortholog prediction (from Ensembl )Paralog prediction (from Ensembl )Protein motifs (from Interpro ) IPR000315 B-box-type zinc finger IPR001487 Bromodomain IPR001841 Zinc finger, RING-type IPR001965 Zinc finger, PHD-type IPR003649 B-box, C-terminal IPR011011 Zinc finger, FYVE/PHD-type IPR013083 Zinc finger, RING/FYVE/PHD-type IPR017907 Zinc finger, RING-type, conserved site IPR018359 Bromodomain, conserved site IPR019786 Zinc finger, PHD-type, conserved site IPR019787 Zinc finger, PHD-finger IPR036427 Bromodomain-like superfamily
Gene Ontology (GO ) nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process catabolic process regulation of biological quality cell death cell communication response to external stimulus response to chemical cellular response to stimulus response to estrogen nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process catabolic process regulation of biological quality cell death cell communication response to external stimulus response to chemical cellular response to stimulus response to estrogen nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process catabolic process regulation of biological quality cell death cell communication response to external stimulus response to chemical cellular response to stimulus response to estrogen nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process catabolic process regulation of biological quality cell death cell communication response to external stimulus response to chemical cellular response to stimulus response to estrogen nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process catabolic process regulation of biological quality cell death cell communication response to external stimulus response to chemical cellular response to stimulus response to estrogen nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process catabolic process regulation of biological quality cell death cell communication response to external stimulus response to chemical cellular response to stimulus response to estrogen nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process catabolic process regulation of biological quality cell death cell communication response to external stimulus response to chemical cellular response to stimulus response to estrogen nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process catabolic process regulation of biological quality cell death cell communication response to external stimulus response to chemical cellular response to stimulus response to estrogen nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process catabolic process regulation of biological quality cell death cell communication response to external stimulus response to chemical cellular response to stimulus response to estrogen nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process catabolic process regulation of biological quality cell death cell communication response to external stimulus response to chemical cellular response to stimulus response to estrogen nitrogen cnitrogen compound metabolic process biosynthetbiosynthetic process cellular mcellular metabolic process primary meprimary metabolic process organic suorganic substance metabolic process catabolic catabolic process regulationregulation of biological quality cell deathcell death cell commucell communication response tresponse to external stimulus response tresponse to chemical cellular rcellular response to stimulus response tresponse to estrogen protein binding organic cyclic compound binding heterocyclic compound binding chromatin binding transcription coregulator activity catalytic activity, acting on a protein transferase activity ion binding protein binding organic cyclic compound binding heterocyclic compound binding chromatin binding transcription coregulator activity catalytic activity, acting on a protein transferase activity ion binding protein binding organic cyclic compound binding heterocyclic compound binding chromatin binding transcription coregulator activity catalytic activity, acting on a protein transferase activity ion binding protein binding organic cyclic compound binding heterocyclic compound binding chromatin binding transcription coregulator activity catalytic activity, acting on a protein transferase activity ion binding protein binding organic cyclic compound binding heterocyclic compound binding chromatin binding transcription coregulator activity catalytic activity, acting on a protein transferase activity ion binding protein binding organic cyclic compound binding heterocyclic compound binding chromatin binding transcription coregulator activity catalytic activity, acting on a protein transferase activity ion binding protein binding organic cyclic compound binding heterocyclic compound binding chromatin binding transcription coregulator activity catalytic activity, acting on a protein transferase activity ion binding protein binding organic cyclic compound binding heterocyclic compound binding chromatin binding transcription coregulator activity catalytic activity, acting on a protein transferase activity ion binding protein binding organic cyclic compound binding heterocyclic compound binding chromatin binding transcription coregulator activity catalytic activity, acting on a protein transferase activity ion binding protein binding organic cyclic compound binding heterocyclic compound binding chromatin binding transcription coregulator activity catalytic activity, acting on a protein transferase activity ion binding protein bindingprotein binding organic cyclic coorganic cyclic compound binding heterocyclic compheterocyclic compound binding chromatin bindingchromatin binding transcription cortranscription coregulator activity catalytic activitcatalytic activity, acting on a protein transferase activtransferase activity ion bindingion binding cell organelle membrane-enclosed lumen cell organelle membrane-enclosed lumen cell organelle membrane-enclosed lumen cell organelle membrane-enclosed lumen cell organelle membrane-enclosed lumen cell organelle membrane-enclosed lumen cell organelle membrane-enclosed lumen cell organelle membrane-enclosed lumen cell organelle membrane-enclosed lumen cell organelle membrane-enclosed lumen cellcell organelleorganelle membrane-enclosed lumenmembrane-enclosed lumen
Pathways (from Reactome )No match Phenotype (from MGI , Zfin or HPO ) homeostasis/metabolism phenotype tumorigenesis liver/biliary system phenotype cellular phenotype homeostasis/metabolism phenotype tumorigenesis liver/biliary system phenotype cellular phenotype homeostasis/metabolism phenotype tumorigenesis liver/biliary system phenotype cellular phenotype homeostasis/metabolism phenotype tumorigenesis liver/biliary system phenotype cellular phenotype homeostasis/metabolism phenotype tumorigenesis liver/biliary system phenotype cellular phenotype homeostasis/metabolism phenotype tumorigenesis liver/biliary system phenotype cellular phenotype homeostasis/metabolism phenotype tumorigenesis liver/biliary system phenotype cellular phenotype homeostasis/metabolism phenotype tumorigenesis liver/biliary system phenotype cellular phenotype homeostasis/metabolism phenotype tumorigenesis liver/biliary system phenotype cellular phenotype homeostasis/metabolism phenotype tumorigenesis liver/biliary system phenotype cellular phenotype homeostasis/metabolism phenotypehomeostasis/metabolism phenotype tumorigenesistumorigenesis liver/biliary system phenotypeliver/biliary system phenotype cellular phenotypecellular phenotype MP:0001573 abnormal circulating alanine transaminase level "aberrent concentration in the blood of this enzyme, whcih transfers amino groups from l-alanine to 2-ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Slc26a5mpc234H /Slc26a5mpc234H Genetic Background: involves: BALB/c * C3H/HeH * C57BL/6J
MP:0003324 liver adenoma "benign epithelial neoplasm of the liver" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Mmp14tm1Hbh /Mmp14+ ,Mmp16tm1Khol /Mmp16+ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac
MP:0003331 hepatocellular carcinoma "malignant neoplasm arising from liver cells" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Mmp14tm1Hbh /Mmp14+ ,Mmp16tm1Khol /Mmp16+ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac
MP:0003893 increased hepatocyte proliferation "anomalous growth and reproduction of hepatocyte cells of the liver" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Mmp14tm1Hbh /Mmp14+ ,Mmp16tm1Khol /Mmp16+ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTacAllelic Composition: Raratm3.1Ipc /Rara+ ,Trim24tm1.1Los /Trim24tm1.1Los Genetic Background: involves: 129/Sv * C57BL/6 * SJLAllelic Composition: Raratm3Ipc /Raratm3Ipc ,Speer6-ps1Tg(Alb-cre)21Mgn /?,Trim24tm1Los /Trim24tm1Los Genetic Background: involves: 129/Sv * C57BL/6 * DBA * SJLAllelic Composition: Raratm3Ipc /Rara+ ,Speer6-ps1Tg(Alb-cre)21Mgn /?,Trim24tm1Los /Trim24tm1Los Genetic Background: involves: 129/Sv * C57BL/6 * DBA * SJL
MP:0004025 polyploidy "more than two chromosome sets are present" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Mmp14tm1Hbh /Mmp14+ ,Mmp16tm1Khol /Mmp16+ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac
MP:0008019 liver tumor "presence of abnormal, rapidly proliferating cells in the liver usually in the form of a distinct mass" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Mmp14tm1Hbh /Mmp14+ ,Mmp16tm1Khol /Mmp16+ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac
Interacting proteins (from Reactome )No match
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