ENSMUSG00000029915


Mus musculus

Features
Gene ID: ENSMUSG00000029915
  
Biological name :Clec5a
  
Synonyms : Clec5a / C-type lectin domain family 5 member A / Q9R007
  
Possible biological names infered from orthology : C-type lectin domain containing 5A / Q9NY25
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: B1
Gene start: 40574894
Gene end: 40585821
  
Corresponding Affymetrix probe sets: 10544273 (MoGene1.0st)   1421366_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000135240
Ensembl peptide - ENSMUSP00000099030
Ensembl peptide - ENSMUSP00000121848
NCBI entrez gene - 23845     See in Manteia.
MGI - MGI:1345151
RefSeq - NM_001038604
RefSeq - NM_021364
RefSeq Peptide - NP_001033693
RefSeq Peptide - NP_067339
swissprot - A0A0R4J269
swissprot - Q9R007
Ensembl - ENSMUSG00000029915
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000029035Gallus gallus
 CLEC5AENSG00000258227Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR033992  Natural killer cell receptor-like, C-type lectin-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002076 osteoblast development IDA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0030099 myeloid cell differentiation IGI
 biological_processGO:0033033 negative regulation of myeloid cell apoptotic process IDA
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 biological_processGO:0045087 innate immune response ISO
 biological_processGO:0046718 viral entry into host cell IEA
 biological_processGO:0050715 positive regulation of cytokine secretion IMP
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0001618 virus receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
DAP12 interactions
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003436 resistance to induced arthritis "less likely to be striken with changes in the synovial membranes and thickening of articular structures, widespread degeneration of the collagen fibers in connective tissues, and by atrophy and rarefaction of bony structures that are induced by inflammatory responses caused by chemical or mechanical agents" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:75303]
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Allelic Composition: Tubb3tm1.1Ece/Tubb3+
Genetic Background: involves: 129S/SvEv * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000030579 O54885 / Tyrobp / TYRO protein tyrosine kinase binding protein / O43914*  / complex / reaction






 

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