Manteia

ENSMUSG00000030098

Mus musculus

Features

Gene ID:	ENSMUSG00000030098

Biological name :	Grip2

Synonyms :	glutamate receptor interacting protein 2 / Grip2

Possible biological names infered from orthology :

Species:	Mus musculus

Chr. number:	6
Strand:	-1
Band:	D1
Gene start:	91761509
Gene end:	91827250

Corresponding Affymetrix probe sets:	10546370 (MoGene1.0st) 1460028_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000125538 Ensembl peptide - ENSMUSP00000124709 Ensembl peptide - ENSMUSP00000124717 Ensembl peptide - ENSMUSP00000125047 Ensembl peptide - ENSMUSP00000123941 NCBI entrez gene - 243547 See in Manteia. MGI - MGI:2681173 RefSeq - XM_011241351 RefSeq - NM_001159507 RefSeq - XM_006506102 RefSeq - XM_006506103 RefSeq - XM_006506104 RefSeq - XM_006506105 RefSeq Peptide - NP_001152979 swissprot - E0CYS1 swissprot - F7BQ55 swissprot - G3XA20 swissprot - E0CXS4 swissprot - E0CXE0 Ensembl - ENSMUSG00000030098

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Grip1 / Q925T6 / Glutamate receptor-interacting protein 1 / Q9Y3R0*	ENSMUSG00000034813	61

Protein motifs (from Interpro)

Interpro ID	Name
IPR001478	PDZ domain
IPR030029	Glutamate receptor-interacting protein 2
IPR036034	PDZ superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0007219	Notch signaling pathway	IDA
biological_process	GO:0014824	artery smooth muscle contraction	IMP
biological_process	GO:0015031	protein transport	IEA
biological_process	GO:0045777	positive regulation of blood pressure	IMP
cellular_component	GO:0005737	cytoplasm	ISO
cellular_component	GO:0005886	plasma membrane	ISO
cellular_component	GO:0014069	postsynaptic density	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0030425	dendrite	IEA
cellular_component	GO:0045211	postsynaptic membrane	IEA
molecular_function	GO:0005515	protein binding	IEA
molecular_function	GO:0030159	receptor signaling complex scaffold activity	IEA
molecular_function	GO:0035254	glutamate receptor binding	ISO

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000564	syndactyly	"any degree of webbing or fusion of the digits, may involve only soft tissues or also can include bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Deaf1^tm1Sho/Deaf1⁺ Genetic Background: either: (involves: 129/Sv * CD-1) or (involves: 129/Sv * C57BL/6)
MP:0001899	absent long term depression	"lack of the normal, persistent activity-dependent decrease in synaptic efficacy between neurons, often following slow, weak stimulation of CA1 neurons" [Principles of Neural Science:ISBN 0-8385-8034-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Bmi1^{tm1(cre/ERT)Mrc}/Bmi1⁺,Ctnnb1^tm1Mmt/Ctnnb1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0005242	cryptophthalmos	"congenital anomaly in which the skin is continuous over the eyeball without any indication of the formation of eyelids" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83745]	Show Allelic Composition: Grip1^tm1Rha/Grip1^tm1Rha,Grip2^tm1Rha/Grip2^tm1Rha Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr