ENSMUSG00000030137


Mus musculus

Features
Gene ID: ENSMUSG00000030137
  
Biological name :Tuba8
  
Synonyms : Q9JJZ2 / Tuba8 / tubulin, alpha 8
  
Possible biological names infered from orthology : Q9NY65
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: F1
Gene start: 121210696
Gene end: 121226854
  
Corresponding Affymetrix probe sets: 10541301 (MoGene1.0st)   1419518_at (Mouse Genome 430 2.0 Array)   1446771_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000032233
NCBI entrez gene - 53857     See in Manteia.
MGI - MGI:1858225
RefSeq - NM_017379
RefSeq Peptide - NP_059075
swissprot - Q9JJZ2
Ensembl - ENSMUSG00000030137
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tuba4lENSDARG00000074289Danio rerio
 ENSGALG00000013056Gallus gallus
 TUBA8BENSGALG00000013045Gallus gallus
 TUBA8ENSG00000183785Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q3UX10 / Tubal3 / tubulin, alpha-like 3 / A6NHL2*ENSMUSG0000002121673


Protein motifs (from Interpro)
Interpro ID Name
 IPR000217  Tubulin
 IPR002452  Alpha tubulin
 IPR003008  Tubulin/FtsZ, GTPase domain
 IPR008280  Tubulin/FtsZ, C-terminal
 IPR017975  Tubulin, conserved site
 IPR018316  Tubulin/FtsZ, 2-layer sandwich domain
 IPR036525  Tubulin/FtsZ, GTPase domain superfamily
 IPR037103  Tubulin/FtsZ, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization ISA
 biological_processGO:0007017 microtubule-based process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule ISA
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton ISA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Recruitment of NuMA to mitotic centrosomes
Recycling pathway of L1
Cilium Assembly
RHO GTPases activate IQGAPs
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
Carboxyterminal post-translational modifications of tubulin
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Lifrtm1Imx/Lifr+
Genetic Background: B6;129S7-Lifrtm1Imx/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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