Manteia - Molecule gene

ENSMUSG00000030278

Mus musculus

Features

Gene ID:	ENSMUSG00000030278

Biological name :	Cidec

Synonyms :	Cell death activator CIDE-3 / Cidec / P56198

Possible biological names infered from orthology :	cell death inducing DFFA like effector c / Q96AQ7

Species:	Mus musculus

Chr. number:	6
Strand:	-1
Band:	E3
Gene start:	113424634
Gene end:	113435760

Corresponding Affymetrix probe sets:	10546929 (MoGene1.0st) 1452260_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000108714 Ensembl peptide - ENSMUSP00000122068 Ensembl peptide - ENSMUSP00000032416 Ensembl peptide - ENSMUSP00000108712 NCBI entrez gene - 14311 See in Manteia. MGI - MGI:95585 RefSeq - NM_178373 RefSeq - XM_006505531 RefSeq - NM_001301295 RefSeq Peptide - NP_001288224 RefSeq Peptide - NP_848460 swissprot - D3Z1A6 swissprot - P56198 swissprot - E9QMZ0 Ensembl - ENSMUSG00000030278

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
cidec	ENSDARG00000059651	Danio rerio
CIDEC	ENSGALG00000026945	Gallus gallus
CIDEC	ENSG00000187288	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Cidea / O70302 / Cell death activator CIDE-A / O60543* / cell death-inducing DFFA-like effector a*	ENSMUSG00000024526	38
Cideb / O70303 / Cell death activator CIDE-B / Q9UHD4* / cell death-inducing DFFA-like effector b*	ENSMUSG00000022219	37

Protein motifs (from Interpro)

Interpro ID	Name
IPR003508	CIDE-N domain

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006351	transcription, DNA-templated	IEA
biological_process	GO:0006355	regulation of transcription, DNA-templated	IEA
biological_process	GO:0006915	apoptotic process	IEA
biological_process	GO:0034389	lipid particle organization	ISO
biological_process	GO:0042981	regulation of apoptotic process	IBA
biological_process	GO:0097194	execution phase of apoptosis	ISS
cellular_component	GO:0005622	intracellular	IEA
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0005783	endoplasmic reticulum	IEA
cellular_component	GO:0005811	lipid droplet	IBA
cellular_component	GO:0005829	cytosol	TAS
molecular_function	GO:0003674	molecular_function	ND

Pathways (from Reactome)

Pathway description

Lipid particle organization

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000005	increased brown fat amount	"increased amount of thermogenic tissue in the body that is composed of cells containing multiple small fat droplets" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:14208]	Show Allelic Composition: Sh3bp2^tm1Rtpl/Sh3bp2^tm1Rtpl Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0001259	abnormal body weight	"anomaly in average weight compared to the norm" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]	Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv
MP:0001399	hyperactivity	"general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]	Show Allelic Composition: Cidec^tm1.1Gonz/Cidec^tm1.2Gonz,Tg(Fabp4-cre)#Abel/? Genetic Background: B6N.Cg-Cidec^tm1.1Gonz/Cidec^tm1.2Gonz Tg(Fabp4-cre)#Abel
MP:0001552	increased circulating triglyceride level	"higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416]	Show Allelic Composition: Cidec^tm1.1Gonz/Cidec^tm1.2Gonz,Tg(Fabp4-cre)#Abel/? Genetic Background: B6N.Cg-Cidec^tm1.1Gonz/Cidec^tm1.2Gonz Tg(Fabp4-cre)#Abel
MP:0001554	increased circulating free fatty acid level	"higher than normal levels of unesterified fatty acids in the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:65146]	Show Allelic Composition: Cidec^tm1.1Gonz/Cidec^tm1.2Gonz,Tg(Fabp4-cre)#Abel/? Genetic Background: B6N.Cg-Cidec^tm1.1Gonz/Cidec^tm1.2Gonz Tg(Fabp4-cre)#Abel
MP:0001783	decreased white fat amount	"reduced quantity of fat-storing cells/tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Cdkn2a^tm1Rdp/Cdkn2a⁺,X/Tg(Tyr-HRAS)60Lc Genetic Background: involves: 129/Sv * C57BL/6J * CBA/J * FVB/N * SJL Allelic Composition: Cidec^tm1.1Gonz/Cidec^tm1.2Gonz,Tg(Fabp4-cre)#Abel/? Genetic Background: B6N.Cg-Cidec^tm1.1Gonz/Cidec^tm1.2Gonz Tg(Fabp4-cre)#Abel
MP:0002079	increased circulating insulin level	"greater than normal levels of insulin in blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Cidec^tm1.1Gonz/Cidec^tm1.2Gonz,Tg(Fabp4-cre)#Abel/? Genetic Background: B6N.Cg-Cidec^tm1.1Gonz/Cidec^tm1.2Gonz Tg(Fabp4-cre)#Abel
MP:0002169	no phenotype detected	"normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ctnna1^Tvrm5/Ctnna1⁺ Genetic Background: C57BL/6J-Ctnna1^Tvrm5/Pjn
MP:0002310	resistance to fatty liver development	"less likely than the norm to to develop hepatic steatosis " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Cdkn2a^tm1Rdp/Cdkn2a⁺,X/Tg(Tyr-HRAS)60Lc Genetic Background: involves: 129/Sv * C57BL/6J * CBA/J * FVB/N * SJL
MP:0002628	fatty liver	"an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Cidec^tm1.1Gonz/Cidec^tm1.2Gonz,Tg(Fabp4-cre)#Abel/? Genetic Background: B6N.Cg-Cidec^tm1.1Gonz/Cidec^tm1.2Gonz Tg(Fabp4-cre)#Abel
MP:0002644	decreased circulating triglyceride level	"lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv Allelic Composition: Cidec^tm1Pli/Cidec^tm1Pli,Lep^ob/Lep^ob Genetic Background: involves: STOCK Mlph^ln a Tgfa^wa1 Cdh23^v Ednrb^s
MP:0002702	decreased circulating free fatty acid level	"lower than normal levels of unesterified fatty acids in the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv Allelic Composition: Cidec^tm1Pli/Cidec^tm1Pli,Lep^ob/Lep^ob Genetic Background: involves: STOCK Mlph^ln a Tgfa^wa1 Cdh23^v Ednrb^s
MP:0002891	increased insulin sensitivity	"greater ability to clear glucose from the bloodstream when given insulin than normal; can result in hypoglycemia" [RGD:Rat Genome Database submission]	Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv Allelic Composition: Cidec^tm1Pli/Cidec^tm1Pli,Lep^ob/Lep^ob Genetic Background: involves: STOCK Mlph^ln a Tgfa^wa1 Cdh23^v Ednrb^s
MP:0002941	increased circulating alanine transaminase level	"increased concentration in the blood of this enzyme, which transfers amino groups from l-alanine to 2 ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Cidec^tm1.1Gonz/Cidec^tm1.2Gonz,Tg(Fabp4-cre)#Abel/? Genetic Background: B6N.Cg-Cidec^tm1.1Gonz/Cidec^tm1.2Gonz Tg(Fabp4-cre)#Abel
MP:0002970	abnormal white fat morphology	"structural aberration in the connective tissue consisting of fat-storing cells and arranged in lobular groups or along minor blood vessels" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Cidec^tm1Maka/Cidec^tm1Maka Genetic Background: B6.129P2-Cidec^tm1Maka Allelic Composition: Cidec^tm1.1Gonz/Cidec^tm1.2Gonz,Tg(Fabp4-cre)#Abel/? Genetic Background: B6N.Cg-Cidec^tm1.1Gonz/Cidec^tm1.2Gonz Tg(Fabp4-cre)#Abel
MP:0002971	abnormal brown fat morphology	"defect in the thermogenic form of adipose tissue" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv Allelic Composition: Cidec^tm1Maka/Cidec^tm1Maka Genetic Background: B6.129P2-Cidec^tm1Maka
MP:0003213	resistance to age related obesity	"reduced probability of excessive weight gain that is progressive with age" [RGD:Rat Genome Database submission]	Show Allelic Composition: Cidec^tm1Maka/Cidec^tm1Maka Genetic Background: B6.129P2-Cidec^tm1Maka
MP:0003458	decreased circulating ketone body level	"less than the normal amount of acetoacetate, 3-hydroxybutyrate and acteone in the blood; produced by fatty acid and carbohydrate metabolism and seen in conditions such as starvation and diabetes mellitus" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv
MP:0003949	abnormal circulating lipid level	"anomalous concentrations of fat-soluble substances (molecules composed of carbon and hydrogen and are characteristically insoluble in water) in the blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Cidec^tm1.1Gonz/Cidec^tm1.2Gonz,Tg(Fabp4-cre)#Abel/? Genetic Background: B6N.Cg-Cidec^tm1.1Gonz/Cidec^tm1.2Gonz Tg(Fabp4-cre)#Abel
MP:0003960	increased lean body mass	"more than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]	Show Allelic Composition: Cidec^tm1.1Gonz/Cidec^tm1.2Gonz,Tg(Fabp4-cre)#Abel/? Genetic Background: B6N.Cg-Cidec^tm1.1Gonz/Cidec^tm1.2Gonz Tg(Fabp4-cre)#Abel
MP:0004889	increased energy expenditure	"increase in the number of calories used per unit time or decrease in weight gain for a given amount of food eaten" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Cidec^tm1Maka/Cidec^tm1Maka Genetic Background: B6.129P2-Cidec^tm1Maka Allelic Composition: Cidec^tm1.1Gonz/Cidec^tm1.2Gonz,Tg(Fabp4-cre)#Abel/? Genetic Background: B6N.Cg-Cidec^tm1.1Gonz/Cidec^tm1.2Gonz Tg(Fabp4-cre)#Abel
MP:0005289	increased oxygen consumption	"greater than the normal rate at which oxygen enters the blood from alveolar gas; this is equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv Allelic Composition: Cidec^tm1Maka/Cidec^tm1Maka Genetic Background: B6.129P2-Cidec^tm1Maka Allelic Composition: Cidec^tm1.1Gonz/Cidec^tm1.2Gonz,Tg(Fabp4-cre)#Abel/? Genetic Background: B6N.Cg-Cidec^tm1.1Gonz/Cidec^tm1.2Gonz Tg(Fabp4-cre)#Abel
MP:0005292	improved glucose tolerance	"better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv Allelic Composition: Cidec^tm1Pli/Cidec^tm1Pli,Lep^ob/Lep^ob Genetic Background: involves: STOCK Mlph^ln a Tgfa^wa1 Cdh23^v Ednrb^s Allelic Composition: Cidec^tm1Maka/Cidec^tm1Maka Genetic Background: B6.129P2-Cidec^tm1Maka
MP:0005331	insulin resistance	"diminished effectiveness of insulin in lowering plasma glucose levels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:84260, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Cidec^tm1.1Gonz/Cidec^tm1.2Gonz,Tg(Fabp4-cre)#Abel/? Genetic Background: B6N.Cg-Cidec^tm1.1Gonz/Cidec^tm1.2Gonz Tg(Fabp4-cre)#Abel
MP:0005334	abnormal fat pad	"malformed or aberrant size of the encapsulated adipose tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv
MP:0005335	abnormal gonadal fat pad	"malformed or aberrant size of the encapsulated adipose tissue associated with the ovaries or testes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:84541]	Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv Allelic Composition: Cidec^tm1Pli/Cidec^tm1Pli,Lep^ob/Lep^ob Genetic Background: involves: STOCK Mlph^ln a Tgfa^wa1 Cdh23^v Ednrb^s
MP:0005452	abnormal body fat amount	"more or less than the normal total amount of connective tissue composed of fat cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Cidec^tm1Pli/Cidec^tm1Pli,Lep^ob/Lep^ob Genetic Background: involves: STOCK Mlph^ln a Tgfa^wa1 Cdh23^v Ednrb^s
MP:0005459	decreased percent body fat	"less fat, relative to the norm, as a percentage of total body weight" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Cidec^tm1.1Gonz/Cidec^tm1.2Gonz,Tg(Fabp4-cre)#Abel/? Genetic Background: B6N.Cg-Cidec^tm1.1Gonz/Cidec^tm1.2Gonz Tg(Fabp4-cre)#Abel
MP:0005533	increased body temperature	"greater than the level of heat natural to a living being" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]	Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv
MP:0005560	decreased circulating glucose level	"less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Cidec^tm1Maka/Cidec^tm1Maka Genetic Background: B6.129P2-Cidec^tm1Maka
MP:0005659	resistance to diet-induced obesity	"less likely to become excessively fat or to increase fat in the subcutaneous connective tissue as a result of consuming a diet geared to increase body fat " [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator]	Show Allelic Composition: Cidec^tm1Maka/Cidec^tm1Maka Genetic Background: B6.129P2-Cidec^tm1Maka Allelic Composition: Cidec^tm1.1Gonz/Cidec^tm1.2Gonz,Tg(Fabp4-cre)#Abel/? Genetic Background: B6N.Cg-Cidec^tm1.1Gonz/Cidec^tm1.2Gonz Tg(Fabp4-cre)#Abel
MP:0005668	decreased circulating leptin level	"less than the normal blood concentration of the peptide hormone secreted by white adipocytes and believed to regulate food intake and energy balance" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, J:34751]	Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv Allelic Composition: Cidec^tm1Maka/Cidec^tm1Maka Genetic Background: B6.129P2-Cidec^tm1Maka
MP:0005670	abnormal white fat physiology	"functional aberration in the connective tissue consisting of fat-storing cells and arranged in lobular groups or along minor blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Cidec^tm1.1Gonz/Cidec^tm1.2Gonz,Tg(Fabp4-cre)#Abel/? Genetic Background: B6N.Cg-Cidec^tm1.1Gonz/Cidec^tm1.2Gonz Tg(Fabp4-cre)#Abel
MP:0008034	enhanced lipolysis	"increase in the rate of the hydrolysis of fat into free fatty acids " [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv Allelic Composition: Cidec^tm1Maka/Cidec^tm1Maka Genetic Background: B6.129P2-Cidec^tm1Maka
MP:0008844	decreased subcutaneous adipose tissue amount	"reduction in amount of adipose tissue beneath the skin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv Allelic Composition: Cidec^tm1Maka/Cidec^tm1Maka Genetic Background: B6.129P2-Cidec^tm1Maka
MP:0009115	abnormal fat cell morphology	"any structural anomaly of a fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals" [CL:0000449]	Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv
MP:0009117	abnormal white fat cell morphology	"any structural anomaly of fat cells with light coloration and few mitochondria; these contain a scant ring of cytoplasm surrounding a single large lipid droplet or vacuole" [MESH:A11.329.114.500]	Show Allelic Composition: Cidec^tm1.1Gonz/Cidec^tm1.2Gonz,Tg(Fabp4-cre)#Abel/? Genetic Background: B6N.Cg-Cidec^tm1.1Gonz/Cidec^tm1.2Gonz Tg(Fabp4-cre)#Abel
MP:0009133	decreased white fat cell size	"reduction in the size of fat cells with light coloration and few mitochondria" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Cidec^tm1.1Gonz/Cidec^tm1.2Gonz,Tg(Fabp4-cre)#Abel/? Genetic Background: B6N.Cg-Cidec^tm1.1Gonz/Cidec^tm1.2Gonz Tg(Fabp4-cre)#Abel
MP:0009283	decreased gonadal fat pad weight	"less than average weight of the encapsulated adipose tissue associated with the ovaries or testes" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv
MP:0009293	decreased inguinal fat pad weight		Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv
MP:0009299	decreased mesenteric fat pad weight		Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv
MP:0009305	decreased retroperitoneal fat pad weight		Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv
MP:0009642	abnormal blood homeostasis	"anomaly in the processes involved in the maintenance of an internal equilibrium of various functions or chemical or protein composition of the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv
MP:0010025	decreased total body fat amount	"less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv
MP:0010378	increased respiratory quotient	"increase in the ratio of the volume of carbon dioxide released to oxygen consumed by a body tissue or an organism compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Cidec^tm1Maka/Cidec^tm1Maka Genetic Background: B6.129P2-Cidec^tm1Maka
MP:0010379	decreased respiratory quotient	"reduction in the ratio of the volume of carbon dioxide released to oxygen consumed by a body tissue or an organism compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Cidec^tm1.1Gonz/Cidec^tm1.2Gonz,Tg(Fabp4-cre)#Abel/? Genetic Background: B6N.Cg-Cidec^tm1.1Gonz/Cidec^tm1.2Gonz Tg(Fabp4-cre)#Abel
MP:0011019	abnormal adaptive thermogenesis	"anomaly in the regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature, often resulting in metabolic inefficiency or death" [PMID:16836744]	Show Allelic Composition: Cidec^tm1.1Gonz/Cidec^tm1.2Gonz,Tg(Fabp4-cre)#Abel/? Genetic Background: B6N.Cg-Cidec^tm1.1Gonz/Cidec^tm1.2Gonz Tg(Fabp4-cre)#Abel
MP:0011049	impaired adaptive thermogenesis	"inability or reduced ability to produce heat in response to short term environmental changes, such as stress, diet or reduced temperature, often resulting in metabolic inefficiency or death" [MGI:csmith, PMID:16836744]	Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv
MP:0011939	increased food intake	"increase in the total number of calories/food amount taken in over time when compared to the normal state" [MGI:csmith]	Show Allelic Composition: Krt14^tm1Efu/Krt14^tm1Efu Genetic Background: involves: 129/Sv
MP:0030016	increased adipocyte glucose uptake	"increased ability of adipocytes to take in glucose" [MGI:anna]	Show Allelic Composition: Cidec^tm1.1Gonz/Cidec^tm1.2Gonz,Tg(Fabp4-cre)#Abel/? Genetic Background: B6N.Cg-Cidec^tm1.1Gonz/Cidec^tm1.2Gonz Tg(Fabp4-cre)#Abel

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSMUSG00000024526	Cidea / O70302 / Cell death activator CIDE-A / O60543* / cell death-inducing DFFA-like effector a*	/ complex

0 s.

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