MP:0000111 | cleft palate | "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
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Allelic Composition: C3tm1Hrc/C3tm1Hrc,Lepob/Lepob Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Oca2p-4THO-II/Oca2p-4THO-II Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-4THO-II/Oca2p-8FDFoD Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-226THO-I/Oca2p-4THO-II Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-116G/Oca2p-116G Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-96H/Oca2p Genetic Background: involves: 101/H
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MP:0000180 | abnormal circulating cholesterol level | "anomalous concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Oca2p-30PUb/Oca2p-30PUb Genetic Background: Not Specified
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MP:0000184 | abnormal circulating HDL cholesterol level | "anomalous concentration in the blood of high denisty lipoprotein; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Oca2p-30PUb/Oca2p-30PUb Genetic Background: Not Specified
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MP:0000371 | diluted coat color | "a coat color that appears lighter in intensity or paler than normal" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Dysftm1Kcam/Dysftm1Kcam Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Lystbg-slt/Lystbg-slt,Myo5ad/Myo5ad,Oca2p/Oca2p,Tyrp1b/Tyrp1b Genetic Background: involves: CT/Ch * YZ57/Ch
Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-dn/Oca2p-dn Genetic Background: Not Specified
Allelic Composition: Oca2p-cp/Oca2p-cp Genetic Background: Not Specified
Allelic Composition: Oca2p-J/Oca2p-J Genetic Background: C3H/HeJ-Oca2p-J/J
Allelic Composition: Oca2p-un/Oca2p-un Genetic Background: C57BL/6J-Oca2p-un
Allelic Composition: Oca2p-bs/Oca2p-bs Genetic Background: Not Specified
Allelic Composition: Oca2p-cas/Oca2p-cas Genetic Background: M. m. castaneus
Allelic Composition: Oca2p-Btlr/Oca2p-Btlr Genetic Background: C57BL/6J-Oca2p-Btlr
Allelic Composition: Oca2p-2Btlr/Oca2p-2Btlr Genetic Background: C57BL/6J-Oca2p-2Btlr
Allelic Composition: Oca2p-3Btlr/Oca2p-3Btlr Genetic Background: C57BL/6J-Oca2p-3Btlr
Allelic Composition: Oca2p-4Btlr/Oca2p-4Btlr Genetic Background: C57BL/6J-Oca2p-4Btlr
Allelic Composition: a/a,Myo5ad/Myo5a+,Oca2p/Oca2+,Tyrp1B-lt/Tyrp1+ Genetic Background: involves: C58 * CT/Ch
Allelic Composition: Oca2p-12DTR/Oca2p-12DTR Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-12DTR/Oca2p Genetic Background: Not Specified
Allelic Composition: Oca2p-x/Oca2p-x Genetic Background: C3H101H-Oca2p-x/H
Allelic Composition: Oca2p-9J/Oca2p-9J Genetic Background: B10.A-H2h2/(2R)SgSnJ
Allelic Composition: Oca2p-25H/Oca2p-25H Genetic Background: Not Specified
Allelic Composition: Oca2p-15J/Oca2p-15J Genetic Background: C57BL/6
Allelic Composition: Oca2p-18J/Oca2p-18J Genetic Background: B10.Cg-H2r H2-T18b Oca2p-18J/GrsrJ
Allelic Composition: Oca2p-78H/Oca2p Genetic Background: involves: C3H/HeH
Allelic Composition: Oca2p-80H/Oca2p-80H Genetic Background: involves: C3H/HeH
Allelic Composition: Oca2p-85H/Oca2p-85H Genetic Background: involves: C3H/HeH
Allelic Composition: Oca2p-83H/Oca2p-84H Genetic Background: involves: C3H/HeH
Allelic Composition: Oca2p-d/Oca2p-d Genetic Background: Not Specified
Allelic Composition: Oca2p-5Btlr/Oca2p-5Btlr Genetic Background: C57BL/6J-Oca2p-5Btlr
Allelic Composition: Oca2p-6Btlr/Oca2p-6Btlr Genetic Background: C57BL/6J-Oca2p-6Btlr
Allelic Composition: Oca2p-7Btlr/Oca2p-7Btlr Genetic Background: C57BL/6J-Oca2p-7Btlr
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MP:0000421 | mottled coat | "coat has spots, streaks, and/or blotches of a different color" [J:17194] |
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Allelic Composition: Oca2p-un/Oca2p-un Genetic Background: C57BL/6J-Oca2p-un
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MP:0000423 | delayed hair regrowth | "slow initiation and asynchrony of the hair growth cycle (anagen) after catagen phase " [J:61509] |
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Allelic Composition: Lystbg-slt/Lystbg-slt,Myo5ad/Myo5ad,Oca2p/Oca2p,Tyrp1b/Tyrp1b Genetic Background: involves: CT/Ch * YZ57/Ch
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MP:0000427 | abnormal hair cycle | "aberrant growth or asynchronous timing of the hair growth " [J:65302] |
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Allelic Composition: Lystbg-slt/Lystbg-slt,Myo5ad/Myo5ad,Oca2p/Oca2p,Tyrp1b/Tyrp1b Genetic Background: involves: CT/Ch * YZ57/Ch
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MP:0000745 | tremors | "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Oca2p-12DTR/Oca2p-12DTR Genetic Background: involves: 101/Rl * C3H/Rl
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MP:0001124 | abnormal gametes | "anomaly of any mature reproductive cell, ovum or spermatozoon, capable of fusing with a cell of similar origin, but opposite sex, to produce a zygote" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
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MP:0001147 | small testis | "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959] |
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Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-25H/Oca2p-25H Genetic Background: Not Specified
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MP:0001153 | small seminiferous tubules | "reduced diameter of the tubules in the testes where spermatogenesis occurs" [J:50844] |
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Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-25H/Oca2p-25H Genetic Background: Not Specified
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MP:0001156 | abnormal spermatogenesis | "incomplete maturation or aberrant formation of the male gametes" [J:58959] |
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Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
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MP:0001260 | increased body weight | "greater than normal average weight " [J:33400] |
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Allelic Composition: Oca2p-30PUb/Oca2p-30PUb Genetic Background: Not Specified
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MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-103G/Oca2p-103G Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-25H/Oca2p-25H Genetic Background: Not Specified
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MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Ttc26hop-hpy/Ttc26hop-hpy,Oca2p-s/Oca2p-s Genetic Background: Not Specified
Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-103G/Oca2p-103G Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-bs/Oca2p-bs Genetic Background: Not Specified
Allelic Composition: Oca2p-12DTR/Oca2p-12DTR Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-25H/Oca2p-25H Genetic Background: Not Specified
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MP:0001324 | abnormal eye pigmentation | "change in the normal black pigmentation of the eye to another color, or lack of color" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Lystbg-slt/Lystbg-slt,Oca2p/Oca2p Genetic Background: involves: CT/Ch * YZ57/Ch
Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-7R/Oca2p-7R Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p/Oca2p-7R Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-103G/Oca2p-103G Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p/Oca2p-103G Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-un/Oca2p-un Genetic Background: C57BL/6J-Oca2p-un
Allelic Composition: Oca2p-un/Oca2p-un+J Genetic Background: C57BL/6J-Oca2p-un
Allelic Composition: Oca2p-un+J/Oca2p-un+J Genetic Background: C57BL/6J-Oca2p-un
Allelic Composition: Oca2p-cas/Oca2p-cas Genetic Background: M. m. castaneus
Allelic Composition: Oca2p-x/Oca2p-x Genetic Background: C3H101H-Oca2p-x/H
Allelic Composition: Oca2p-un+2J/Oca2p-un+2J Genetic Background: C57BL/6J-Oca2p-un
Allelic Composition: Oca2p-un+3J/Oca2p-un+3J Genetic Background: C57BL/6J-Oca2p-un
Allelic Composition: Oca2p-65H/Oca2p Genetic Background: involves: C3H/HeH
Allelic Composition: Oca2p-65H/Oca2p-65H Genetic Background: involves: C3H/HeH
Allelic Composition: Oca2p-66H/Oca2p Genetic Background: involves: 101/H
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MP:0001384 | abnormal pup retrieval | "a mother does not retrieve stray pups to the nest or delays retrieving stray pups" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Oca2p-25H/Oca2p-25H Genetic Background: Not Specified
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MP:0001386 | abnormal maternal nurturing | "failure of mothers to tend offspring" [J:39801] |
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Allelic Composition: Oca2p-s/Oca2p-s Genetic Background: Not Specified
Allelic Composition: Oca2p-25H/Oca2p-25H Genetic Background: Not Specified
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MP:0001405 | impaired coordination | "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-25H/Oca2p-25H Genetic Background: Not Specified
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MP:0001406 | abnormal gait | "unusual or distinctive way of walking" [J:65038] |
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Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
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MP:0001516 | abnormal motor coordination/ balance | "altered ability of an animal to maintain skillful and effective interaction of movements or maintenance of equilibrium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Oca2p-s/Oca2p-s Genetic Background: Not Specified
Allelic Composition: Oca2p-bs/Oca2p-bs Genetic Background: Not Specified
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MP:0001552 | increased circulating triglyceride level | "higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416] |
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Allelic Composition: Oca2p-30PUb/Oca2p-30PUb Genetic Background: Not Specified
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MP:0001559 | hyperglycemia | "abnormally high concentration of glucose in the blood; generally refers to a pathological state" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Oca2p-30PUb/Oca2p-30PUb Genetic Background: Not Specified
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MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Oca2p-cp/Oca2p-cp Genetic Background: Not Specified
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MP:0001922 | reduced male fertility | "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340] |
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Allelic Composition: Oca2p-bs/Oca2p-bs Genetic Background: Not Specified
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MP:0001924 | infertility | "inability to produce live offspring" [J:47225] |
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Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
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MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: Ttc26hop-hpy/Ttc26hop-hpy,Oca2p-s/Oca2p-s Genetic Background: Not Specified
Allelic Composition: Oca2p-s/Oca2p-s Genetic Background: Not Specified
Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-103G/Oca2p-103G Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-12DTR/Oca2p-12DTR Genetic Background: involves: 101/Rl * C3H/Rl
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MP:0001926 | female infertility | "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
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Allelic Composition: Oca2p-12DTR/Oca2p-12DTR Genetic Background: involves: 101/Rl * C3H/Rl
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MP:0001929 | abnormal gametogenesis | "defective formation or differentiation of germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:42324] |
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Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
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MP:0001931 | abnormal oogenesis | "atypical formation or failure to form the female germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782] |
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Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
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MP:0001932 | abnormal spermiogenesis | "failure of sperm cells to form or differentiate" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ttc26hop-hpy/Ttc26hop-hpy,Oca2p-s/Oca2p-s Genetic Background: Not Specified
Allelic Composition: Oca2p-s/Oca2p-s Genetic Background: Not Specified
Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-bs/Oca2p-bs Genetic Background: Not Specified
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MP:0001935 | reduced litter size | "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Otcspf-ash/Y Genetic Background: B6EiC3Sn a/A-Otcspf-ash/J
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MP:0001940 | testicular hypoplasia | "decreased cell number in the testicles" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-25H/Oca2p-25H Genetic Background: Not Specified
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MP:0002058 | neonatal lethality | "death of animal within one day after birth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Oca2p-4THO-II/Oca2p-4THO-II Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-4THO-II/Oca2p-8FDFoD Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-226THO-I/Oca2p-4THO-II Genetic Background: involves: 101/Rl * C3H/Rl
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MP:0002066 | abnormal motor capabilities/coordination/movement | "altered ability to coordinate voluntary movement or repetitive, compulsive movements" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Crb1tm1Wij/Crb1tm2Wij Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0002075 | abnormal coat color | "irregular or unusual pigmentation pattern of the hair in relation to control animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Oca2p/Oca2p,Tyrc-i/Tyrc-i Genetic Background: involves: STOCK Tyrc-r
Allelic Composition: Oca2p-un/Oca2p-un Genetic Background: C57BL/6J-Oca2p-un
Allelic Composition: Oca2p-cas/Oca2p-cas Genetic Background: M. m. castaneus
Allelic Composition: a/a,Oca2p/Oca2p Genetic Background: Not Specified
Allelic Composition: Oca2p/Oca2p-80K Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p/Oca2p-8FDFoD Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p/Oca2p-116G Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-55H/Oca2p Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-61H/Oca2p Genetic Background: involves: 101/H
Allelic Composition: Oca2p-66H/Oca2p Genetic Background: involves: 101/H
Allelic Composition: Oca2p-66H/Oca2p-66H Genetic Background: involves: 101/H
Allelic Composition: Oca2p-80H/Oca2p Genetic Background: involves: C3H/HeH
Allelic Composition: Oca2p-80H/Oca2p-80H Genetic Background: involves: C3H/HeH
Allelic Composition: Oca2p-83H/Oca2p Genetic Background: involves: C3H/HeH
Allelic Composition: Oca2p-85H/Oca2p Genetic Background: involves: C3H/HeH
Allelic Composition: Oca2p-85H/Oca2p-85H Genetic Background: involves: C3H/HeH
Allelic Composition: Oca2p-91H/Oca2p Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-92H/Oca2p-92H Genetic Background: involves: 101/H
Allelic Composition: Oca2p-93H/Oca2p Genetic Background: involves: 101/H
Allelic Composition: Oca2p-95H/Oca2p Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-98H/Oca2p Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-86H/Oca2p Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-87H/Oca2p Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-88H/Oca2p Genetic Background: involves: 101/H
Allelic Composition: Oca2p-d/Oca2p-d Genetic Background: Not Specified
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MP:0002078 | abnormal glucose homeostasis | "anomaly in the state of equilibrium or processing in the body with respect to glucose in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Oca2p-30PUb/Oca2p-30PUb Genetic Background: Not Specified
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MP:0002079 | increased circulating insulin level | "greater than normal levels of insulin in blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Oca2p-30PUb/Oca2p-30PUb Genetic Background: Not Specified
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MP:0002080 | prenatal lethality | "death anytime between fertilization and E18.5" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Oca2p-dn/Oca2p-dn Genetic Background: Not Specified
Allelic Composition: Oca2p-132G/Oca2p-132G Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-96H/Oca2p-96H Genetic Background: involves: 101/H
Allelic Composition: Oca2p-81H/Oca2p-81H Genetic Background: involves: C3H/HeH
Allelic Composition: Oca2p-82H/Oca2p-82H Genetic Background: involves: C3H/HeH
Allelic Composition: Oca2p-87H/Oca2p-87H Genetic Background: involves: 101/H * C3H/HeH
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MP:0002081 | perinatal lethality | "death anytime between E18.5 and postnatal day 1 " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Oca2p-4THO-II/Oca2p-4THO-II Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-48PB/Oca2p-48PB Genetic Background: involves: 101/Rl * C3H/Rl
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MP:0002082 | postnatal lethality | "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Oca2p-132G/Oca2p-132G Genetic Background: involves: 101/Rl * C3H/Rl
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MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ttc26hop-hpy/Ttc26hop-hpy,Oca2p-s/Oca2p-s Genetic Background: Not Specified
Allelic Composition: Oca2p-s/Oca2p-s Genetic Background: Not Specified
Allelic Composition: Oca2p-103G/Oca2p-103G Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-12DTR/Oca2p-12DTR Genetic Background: involves: 101/Rl * C3H/Rl
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MP:0002089 | abnormal postnatal growth/weight/body size | "increased or decreased average body size, weight or growth characteristic abnormalities manifesting after birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Oca2p-bs/Oca2p-bs Genetic Background: Not Specified
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MP:0002118 | abnormal lipid homeostasis | "anomaly in the state of equilibrium in the body with respect to lipids in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Oca2p-30PUb/Oca2p-30PUb Genetic Background: Not Specified
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MP:0002161 | abnormal fertility/fecundity | "reduced ability or inability to produce live offspring" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Oca2p-bs/Oca2p-bs Genetic Background: Not Specified
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MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Oca2p-61H/Oca2p Genetic Background: involves: 101/H
Allelic Composition: Oca2p-78H/Oca2p-78H Genetic Background: involves: C3H/HeH
Allelic Composition: Oca2p-92H/Oca2p Genetic Background: involves: 101/H
Allelic Composition: Oca2p-95H/Oca2p-95H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-97H/Oca2p-97H Genetic Background: involves: 101/H * C3H/HeH
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MP:0002412 | increased susceptibility to bacterial infection | "greater likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Oca2p-3Btlr/Oca2p-3Btlr Genetic Background: C57BL/6J-Oca2p-3Btlr
Allelic Composition: Oca2p-4Btlr/Oca2p-4Btlr Genetic Background: C57BL/6J-Oca2p-4Btlr
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MP:0002628 | fatty liver | "an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Oca2p-30PUb/Oca2p-30PUb Genetic Background: Not Specified
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MP:0002981 | increased liver weight | "a greater than average weight of the bile-secreting exocrine gland" [il:Ira Lu , Mouse Genome Informatics Curator] |
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Allelic Composition: Htr1atm1Tct/Htr1a+ Genetic Background: involves: 129X1/SvJ * C57BL/6J
Allelic Composition: Oca2p-30PUb/Oca2p-x Genetic Background: Not Specified
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MP:0003136 | yellow coat color | "amount and distribution of yellow pigment (phaeomelanin) relative to black or brown pigment (eumelanin) is increased compared to wild-type agouti" [llw2:Linda L. Washburn, Mouse Genome Informatics Curator] |
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Allelic Composition: Oca2p-cas/Oca2p-cas Genetic Background: M. m. castaneus
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MP:0003171 | phenotypic reversion | "reverse mutation to wild-type phenotype from a previously characterized mutant phenotype" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Oca2p-un/Oca2p-un+J Genetic Background: C57BL/6J-Oca2p-un
Allelic Composition: Oca2p-un+J/Oca2p-un+J Genetic Background: C57BL/6J-Oca2p-un
Allelic Composition: Oca2p-un+2J/Oca2p-un+2J Genetic Background: C57BL/6J-Oca2p-un
Allelic Composition: Oca2p-un+3J/Oca2p-un+3J Genetic Background: C57BL/6J-Oca2p-un
Allelic Composition: Oca2p-un+4J/Oca2p-un+4J Genetic Background: C57BL/6J-Oca2p-un
Allelic Composition: Oca2p-un+5J/Oca2p-un+5J Genetic Background: C57BL/6J-Oca2p-un
Allelic Composition: Oca2p-un+6J/Oca2p-un+6J Genetic Background: C57BL/6J-Oca2p-un
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MP:0003492 | abnormal involuntary movement | "anomalies in movements that occur independent of planning (eg. reflexive behavior)" [Nmice:Neuromice Consortium Submission] |
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Allelic Composition: Oca2p-12DTR/Oca2p-12DTR Genetic Background: involves: 101/Rl * C3H/Rl
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MP:0003917 | increased kidney weight | "greater heft of the organs responsible for urine secretion" [RGD:Rat Genome Database submission] |
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Allelic Composition: Htr1atm1Tct/Htr1a+ Genetic Background: involves: 129X1/SvJ * C57BL/6J
Allelic Composition: Oca2p-30PUb/Oca2p-x Genetic Background: Not Specified
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MP:0004381 | abnormal hair follicle melanocyte morphology | "any structural anomaly of the cells that produce pigment in the hair follicles" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: a/a,Oca2p/Oca2p Genetic Background: Not Specified
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MP:0004901 | decreased male germ cell number | "reduced numbers of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-25H/Oca2p-25H Genetic Background: Not Specified
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MP:0004952 | increased spleen weight | "greater than average weight of the organ that functions to filter blood and to store red corpuscles and platelets" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Htr1atm1Tct/Htr1a+ Genetic Background: involves: 129X1/SvJ * C57BL/6J
Allelic Composition: Oca2p-30PUb/Oca2p-x Genetic Background: Not Specified
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MP:0005072 | abnormal hair follicle melanin granule | "anomalous pigment paricles in the hair follicles" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: a/a,Oca2p/Oca2p Genetic Background: Not Specified
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MP:0005075 | abnormal melanosome morphology | "anomalous structure of these tissue-specific cytoplasmic organelles within which melanin pigments are synthesized and stored" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:5346] |
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Allelic Composition: Sox11tm1Weg/Sox11tm1Weg Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Allelic Composition: a/a,Lystbg/Lystbg,Oca2p-J/Oca2p-J Genetic Background: involves: C3H/HeJ * C3H/Rl * C57BL/6J
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MP:0005077 | abnormal melanogenesis | "failure of or anomaly in the biosynthetic pathway of melanin formation in cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:5346] |
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Allelic Composition: a/a,Oca2p-J/Oca2p-J Genetic Background: involves: C3H/HeJ
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MP:0005114 | premature hair loss | "release of fur at an earlier than expected time" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Lystbg-slt/Lystbg-slt,Myo5ad/Myo5ad,Oca2p/Oca2p,Tyrp1b/Tyrp1b Genetic Background: involves: CT/Ch * YZ57/Ch
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MP:0005172 | lack of eye pigmentation | "visual organs are devoid of coloring pigment in relation to control animals, usually resulting in a red or pink color" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500] |
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Allelic Composition: Oca2p-s/Oca2p-s Genetic Background: Not Specified
Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-dn/Oca2p-dn Genetic Background: Not Specified
Allelic Composition: Oca2p-81H/Oca2p-81H Genetic Background: Not Specified
Allelic Composition: Oca2p-cp/Oca2p-cp Genetic Background: Not Specified
Allelic Composition: Oca2p-J/Oca2p-J Genetic Background: C3H/HeJ-Oca2p-J/J
Allelic Composition: Oca2p-un/Oca2p-un+J Genetic Background: C57BL/6J-Oca2p-un
Allelic Composition: Oca2p-un+J/Oca2p-un+J Genetic Background: C57BL/6J-Oca2p-un
Allelic Composition: Oca2p-12DTR/Oca2p Genetic Background: Not Specified
Allelic Composition: Oca2p-9J/Oca2p-9J Genetic Background: B10.A-H2h2/(2R)SgSnJ
Allelic Composition: Oca2p/Oca2p Genetic Background: Not Specified
Allelic Composition: a/a,Oca2p/Oca2p Genetic Background: Not Specified
Allelic Composition: Oca2p-25H/Oca2p-25H Genetic Background: Not Specified
Allelic Composition: Oca2p-un+2J/Oca2p-un+2J Genetic Background: C57BL/6J-Oca2p-un
Allelic Composition: Oca2p-un+3J/Oca2p-un+3J Genetic Background: C57BL/6J-Oca2p-un
Allelic Composition: Oca2p-15J/Oca2p-15J Genetic Background: C57BL/6
Allelic Composition: Oca2p-18J/Oca2p-18J Genetic Background: B10.Cg-H2r H2-T18b Oca2p-18J/GrsrJ
Allelic Composition: Oca2p-86H/Oca2p Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-87H/Oca2p Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-88H/Oca2p Genetic Background: involves: 101/H
Allelic Composition: Oca2p-d/Oca2p-d Genetic Background: Not Specified
Allelic Composition: Oca2p-5Btlr/Oca2p-5Btlr Genetic Background: C57BL/6J-Oca2p-5Btlr
Allelic Composition: Oca2p-6Btlr/Oca2p-6Btlr Genetic Background: C57BL/6J-Oca2p-6Btlr
Allelic Composition: Oca2p-7Btlr/Oca2p-7Btlr Genetic Background: C57BL/6J-Oca2p-7Btlr
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MP:0005178 | increased total circulating cholesterol level | "greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Oca2p-30PUb/Oca2p-30PUb Genetic Background: Not Specified
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MP:0005366 | variegated coat color | "dappled coloration of the fur; mosaic" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Oca2p-un/Oca2p-un+J Genetic Background: C57BL/6J-Oca2p-un
Allelic Composition: Oca2p-un+J/Oca2p-un+J Genetic Background: C57BL/6J-Oca2p-un
Allelic Composition: Oca2p-un+2J/Oca2p-un+2J Genetic Background: C57BL/6J-Oca2p-un
Allelic Composition: Oca2p-un+3J/Oca2p-un+3J Genetic Background: C57BL/6J-Oca2p-un
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MP:0005409 | darkened coat color | "amount and distribution of yellow pigment (phaeomelanin) relative to black or brown pigment (eumelanin) is decreasesd when compared to wild-type agouti" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Oca2p-7R/Oca2p-7R Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p/Oca2p-7R Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-103G/Oca2p-103G Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p/Oca2p-103G Genetic Background: involves: 101/Rl * C3H/Rl
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MP:0005424 | jerky movement | "continuous, abrupt, faltering motions of the whole body or a portion of the body" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Oca2p-cp/Oca2p-cp Genetic Background: Not Specified
Allelic Composition: Oca2p-bs/Oca2p-bs Genetic Background: Not Specified
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MP:0005578 | teratozoospermia | "presence of malformed spermatozoa in the semen; malformations include the physical bending of the sperm to produce kinks or bends" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator] |
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Allelic Composition: Ttc26hop-hpy/Ttc26hop-hpy,Oca2p-s/Oca2p-s Genetic Background: Not Specified
Allelic Composition: Oca2p-s/Oca2p-s Genetic Background: Not Specified
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MP:0006159 | ocular albinism | "absence of melanin production in the eye only" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Oca2p-Btlr/Oca2p-Btlr Genetic Background: C57BL/6J-Oca2p-Btlr
Allelic Composition: Oca2p-2Btlr/Oca2p-2Btlr Genetic Background: C57BL/6J-Oca2p-2Btlr
Allelic Composition: Oca2p-3Btlr/Oca2p-3Btlr Genetic Background: C57BL/6J-Oca2p-3Btlr
Allelic Composition: Oca2p-4Btlr/Oca2p-4Btlr Genetic Background: C57BL/6J-Oca2p-4Btlr
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MP:0006380 | abnormal spermatid morphology | "anomaly in the number or structure of the male germ cells that without further cell division give rise to mature spermatozoa" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-25H/Oca2p-25H Genetic Background: Not Specified
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MP:0008480 | absent eye pigmentation | "absence of melanin (pigment) in the eye either due to absent melanocytes or failure of melanin synthesis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Oca2p/Oca2p-80K Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p/Oca2p-8FDFoD Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p/Oca2p-116G Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-116G/Oca2p-116G Genetic Background: involves: 101/Rl * C3H/Rl
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MP:0008892 | abnormal sperm flagellum | "any strucutral anomaly of the whiplike posterior filiform portion of the spermatozoon that provides sperm motility" [MESH:A05.360.490.890.840] |
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Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-25H/Oca2p-25H Genetic Background: Not Specified
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MP:0008898 | abnormal acrosome morphology | "any structural anomaly of the cap-like structure at the anterior end of the sperm head that produces enzymes needed for egg penetration" [MESH:A05.360.490.890.820.100] |
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Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-25H/Oca2p-25H Genetic Background: Not Specified
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MP:0008908 | increased total fat pad weight | "greater than average weight of the fat pads" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Htr1atm1Tct/Htr1a+ Genetic Background: involves: 129X1/SvJ * C57BL/6J
Allelic Composition: Oca2p-30PUb/Oca2p-x Genetic Background: Not Specified
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MP:0008912 | nervous | "increased, skittish, behavior induced by stimulation such as handling, touching or noise" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-103G/Oca2p-103G Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-25H/Oca2p-25H Genetic Background: Not Specified
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MP:0009230 | abnormal sperm head morphology | "any structural abnormality of the head segment of the sperm cell which contains the nucleus with densely coiled chromatin fibers, and is surrounded anteriorly by the acrosome which contains enzymes used for penetrating the female egg" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-25H/Oca2p-25H Genetic Background: Not Specified
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MP:0009233 | enlarged sperm head | "increased size of the head segment of the sperm cell" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-25H/Oca2p-25H Genetic Background: Not Specified
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MP:0009554 | abnormal hair follicle melanin granule shape | "the form of pigment polymers in the hair follicle differs compared to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: a/a,Oca2p/Oca2p Genetic Background: Not Specified
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MP:0009555 | abnormal hair follicle melanin granule distribution | "anomaly in the spatial arrangement of particles produced by melanocytes that confer color in the hair follicle" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: a/a,Oca2p/Oca2p Genetic Background: Not Specified
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MP:0010193 | abnormal choroid melanin granule morphology | "any structural anomaly of the pigment particles in the choroid" [ISBN-13:978-1-4051-2034-0 "The Pigmentary System, Second Edition"] |
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Allelic Composition: a/a,Oca2p-J/Oca2p-J Genetic Background: involves: C3H/HeJ
Allelic Composition: a/a,Lystbg/Lystbg,Oca2p-J/Oca2p-J Genetic Background: involves: C3H/HeJ * C3H/Rl * C57BL/6J
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MP:0010389 | mosaic coat color | "a random coat color pattern due to genetically different populations of cells in the skin e.g. as the result of X-inactivation" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Oca2p-un/Oca2p-un Genetic Background: C57BL/6J-Oca2p-un
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MP:0010766 | abnormal NK cell physiology | "any functional anomaly of a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors, and also regulate immune responses via cytokine release and direct contact with other cells" [GOC:add, ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:15771571] |
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Allelic Composition: Oca2p-3Btlr/Oca2p-3Btlr Genetic Background: C57BL/6J-Oca2p-3Btlr
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MP:0011085 | complete postnatal lethality | "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Oca2p-116G/Oca2p-116G Genetic Background: involves: 101/Rl * C3H/Rl
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MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Ttc26hop-hpy/Ttc26hop-hpy,Oca2p-s/Oca2p-s Genetic Background: Not Specified
Allelic Composition: Oca2p-7FR60Lb/Oca2p-7FR60Lb Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-12R250M/Oca2p-12R250M Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-9DTW/Oca2p-9DTW Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-39DSD/Oca2p-39DSD Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-18CoS/Oca2p-18CoS Genetic Background: involves: 101/Rl * C3H/Rl
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MP:0011088 | partial neonatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Oca2p-7FR60Lb/Oca2p-7FR60Lb Genetic Background: involves: 101/Rl * C3H/Rl
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MP:0011090 | partial perinatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith] |
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Allelic Composition: Oca2p-cp/Oca2p-cp Genetic Background: Not Specified
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MP:0011091 | complete prenatal lethality | "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Htr1atm1Tct/Htr1a+ Genetic Background: involves: 129X1/SvJ * C57BL/6J
Allelic Composition: Oca2p-30PUb/Oca2p-30PUb Genetic Background: Not Specified
Allelic Composition: Oca2p-80K/Oca2p-80K Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-8FDFoD/Oca2p-8FDFoD Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Oca2p-55H/Oca2p-55H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-93H/Oca2p-93H Genetic Background: involves: 101/H
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MP:0011100 | complete preweaning lethality | "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith] |
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Allelic Composition: Oca2p-12DTR/Oca2p-12DTR Genetic Background: involves: 101/Rl * C3H/Rl
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MP:0011277 | decreased tail pigmentation | "visually detectable dilution of pigment present on the tail surface" [MGI:csmith] |
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Allelic Composition: a/a,Oca2p/Oca2p Genetic Background: Not Specified
Allelic Composition: Oca2p-66H/Oca2p Genetic Background: involves: 101/H
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MP:0011279 | decreased ear pigmentation | "visually detectable dilution of pigment present in the outer ear" [MGI:csmith] |
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Allelic Composition: Oca2p-x/Oca2p-x Genetic Background: C3H101H-Oca2p-x/H
Allelic Composition: a/a,Oca2p/Oca2p Genetic Background: Not Specified
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MP:0011400 | complete lethality | "all individuals of a given genotype in a population die before the end of the normal lifespan but time(s) of death are unspecified" [MGI:llw2] |
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Allelic Composition: Oca2p-98H/Oca2p Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-99H/Oca2p-99H Genetic Background: involves: 101/H * C3H/HeH
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MP:0011627 | decreased skin pigmentation | "visually detectable dilution of pigment present in the skin" [MGI:csmith] |
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Allelic Composition: a/a,Oca2p/Oca2p Genetic Background: Not Specified
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MP:0020550 | multinucleated giant male germ cells | "presence of large cells containing multiple nuclei formed abnormal opening of the cytoplasmic bridges that are part of normal germ cell division" [PMID:16272280, url:https://ntp.niehs.nih.gov/nnl/male_reproductive/testis/setubmgcel/index.htm] |
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Allelic Composition: Oca2p-6H/Oca2p-6H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Oca2p-25H/Oca2p-25H Genetic Background: Not Specified
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