ENSMUSG00000030450


Mus musculus

Features
Gene ID: ENSMUSG00000030450
  
Biological name :Oca2
  
Synonyms : Oca2 / P protein / Q62052
  
Possible biological names infered from orthology : OCA2 melanosomal transmembrane protein / Q04671
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B5
Gene start: 56239760
Gene end: 56536518
  
Corresponding Affymetrix probe sets: 10553743 (MoGene1.0st)   1418211_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000032633
Ensembl peptide - ENSMUSP00000145823
Ensembl peptide - ENSMUSP00000121798
Ensembl peptide - ENSMUSP00000119529
Ensembl peptide - ENSMUSP00000119099
NCBI entrez gene - 18431     See in Manteia.
MGI - MGI:97454
RefSeq - XM_006540700
RefSeq - NM_021879
RefSeq - XM_006540699
RefSeq Peptide - NP_068679
swissprot - D6RCY7
swissprot - D6RIQ8
swissprot - Q62052
swissprot - D3Z251
swissprot - A0A0U1RP45
Ensembl - ENSMUSG00000030450
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 oca2ENSDARG00000061303Danio rerio
 OCA2ENSGALG00000016740Gallus gallus
 OCA2ENSG00000104044Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004680  Citrate transporter-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007286 spermatid development IMP
 biological_processGO:0008283 cell proliferation IMP
 biological_processGO:0030318 melanocyte differentiation IMP
 biological_processGO:0042438 melanin biosynthetic process IMP
 biological_processGO:0043473 pigmentation IMP
 biological_processGO:0048066 developmental pigmentation IMP
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0033162 melanosome membrane ISO


Pathways (from Reactome)
Pathway description
Melanin biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000111 cleft palate "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
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Allelic Composition: C3tm1Hrc/C3tm1Hrc,Lepob/Lepob
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Oca2p-4THO-II/Oca2p-4THO-II
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-4THO-II/Oca2p-8FDFoD
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-226THO-I/Oca2p-4THO-II
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-116G/Oca2p-116G
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-96H/Oca2p
Genetic Background: involves: 101/H

 MP:0000180 abnormal circulating cholesterol level "anomalous concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Oca2p-30PUb/Oca2p-30PUb
Genetic Background: Not Specified

 MP:0000184 abnormal circulating HDL cholesterol level "anomalous concentration in the blood of high denisty lipoprotein; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Oca2p-30PUb/Oca2p-30PUb
Genetic Background: Not Specified

 MP:0000371 diluted coat color "a coat color that appears lighter in intensity or paler than normal" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Dysftm1Kcam/Dysftm1Kcam
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Lystbg-slt/Lystbg-slt,Myo5ad/Myo5ad,Oca2p/Oca2p,Tyrp1b/Tyrp1b
Genetic Background: involves: CT/Ch * YZ57/Ch

Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-dn/Oca2p-dn
Genetic Background: Not Specified

Allelic Composition: Oca2p-cp/Oca2p-cp
Genetic Background: Not Specified

Allelic Composition: Oca2p-J/Oca2p-J
Genetic Background: C3H/HeJ-Oca2p-J/J

Allelic Composition: Oca2p-un/Oca2p-un
Genetic Background: C57BL/6J-Oca2p-un

Allelic Composition: Oca2p-bs/Oca2p-bs
Genetic Background: Not Specified

Allelic Composition: Oca2p-cas/Oca2p-cas
Genetic Background: M. m. castaneus

Allelic Composition: Oca2p-Btlr/Oca2p-Btlr
Genetic Background: C57BL/6J-Oca2p-Btlr

Allelic Composition: Oca2p-2Btlr/Oca2p-2Btlr
Genetic Background: C57BL/6J-Oca2p-2Btlr

Allelic Composition: Oca2p-3Btlr/Oca2p-3Btlr
Genetic Background: C57BL/6J-Oca2p-3Btlr

Allelic Composition: Oca2p-4Btlr/Oca2p-4Btlr
Genetic Background: C57BL/6J-Oca2p-4Btlr

Allelic Composition: a/a,Myo5ad/Myo5a+,Oca2p/Oca2+,Tyrp1B-lt/Tyrp1+
Genetic Background: involves: C58 * CT/Ch

Allelic Composition: Oca2p-12DTR/Oca2p-12DTR
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-12DTR/Oca2p
Genetic Background: Not Specified

Allelic Composition: Oca2p-x/Oca2p-x
Genetic Background: C3H101H-Oca2p-x/H

Allelic Composition: Oca2p-9J/Oca2p-9J
Genetic Background: B10.A-H2h2/(2R)SgSnJ

Allelic Composition: Oca2p-25H/Oca2p-25H
Genetic Background: Not Specified

Allelic Composition: Oca2p-15J/Oca2p-15J
Genetic Background: C57BL/6

Allelic Composition: Oca2p-18J/Oca2p-18J
Genetic Background: B10.Cg-H2r H2-T18b Oca2p-18J/GrsrJ

Allelic Composition: Oca2p-78H/Oca2p
Genetic Background: involves: C3H/HeH

Allelic Composition: Oca2p-80H/Oca2p-80H
Genetic Background: involves: C3H/HeH

Allelic Composition: Oca2p-85H/Oca2p-85H
Genetic Background: involves: C3H/HeH

Allelic Composition: Oca2p-83H/Oca2p-84H
Genetic Background: involves: C3H/HeH

Allelic Composition: Oca2p-d/Oca2p-d
Genetic Background: Not Specified

Allelic Composition: Oca2p-5Btlr/Oca2p-5Btlr
Genetic Background: C57BL/6J-Oca2p-5Btlr

Allelic Composition: Oca2p-6Btlr/Oca2p-6Btlr
Genetic Background: C57BL/6J-Oca2p-6Btlr

Allelic Composition: Oca2p-7Btlr/Oca2p-7Btlr
Genetic Background: C57BL/6J-Oca2p-7Btlr

 MP:0000421 mottled coat "coat has spots, streaks, and/or blotches of a different color" [J:17194]
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Allelic Composition: Oca2p-un/Oca2p-un
Genetic Background: C57BL/6J-Oca2p-un

 MP:0000423 delayed hair regrowth "slow initiation and asynchrony of the hair growth cycle (anagen) after catagen phase " [J:61509]
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Allelic Composition: Lystbg-slt/Lystbg-slt,Myo5ad/Myo5ad,Oca2p/Oca2p,Tyrp1b/Tyrp1b
Genetic Background: involves: CT/Ch * YZ57/Ch

 MP:0000427 abnormal hair cycle "aberrant growth or asynchronous timing of the hair growth " [J:65302]
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Allelic Composition: Lystbg-slt/Lystbg-slt,Myo5ad/Myo5ad,Oca2p/Oca2p,Tyrp1b/Tyrp1b
Genetic Background: involves: CT/Ch * YZ57/Ch

 MP:0000745 tremors "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Oca2p-12DTR/Oca2p-12DTR
Genetic Background: involves: 101/Rl * C3H/Rl

 MP:0001124 abnormal gametes "anomaly of any mature reproductive cell, ovum or spermatozoon, capable of fusing with a cell of similar origin, but opposite sex, to produce a zygote" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
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Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-25H/Oca2p-25H
Genetic Background: Not Specified

 MP:0001153 small seminiferous tubules "reduced diameter of the tubules in the testes where spermatogenesis occurs" [J:50844]
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Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-25H/Oca2p-25H
Genetic Background: Not Specified

 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
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Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
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Allelic Composition: Oca2p-30PUb/Oca2p-30PUb
Genetic Background: Not Specified

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-103G/Oca2p-103G
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-25H/Oca2p-25H
Genetic Background: Not Specified

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Ttc26hop-hpy/Ttc26hop-hpy,Oca2p-s/Oca2p-s
Genetic Background: Not Specified

Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-103G/Oca2p-103G
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-bs/Oca2p-bs
Genetic Background: Not Specified

Allelic Composition: Oca2p-12DTR/Oca2p-12DTR
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-25H/Oca2p-25H
Genetic Background: Not Specified

 MP:0001324 abnormal eye pigmentation "change in the normal black pigmentation of the eye to another color, or lack of color" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Lystbg-slt/Lystbg-slt,Oca2p/Oca2p
Genetic Background: involves: CT/Ch * YZ57/Ch

Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-7R/Oca2p-7R
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p/Oca2p-7R
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-103G/Oca2p-103G
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p/Oca2p-103G
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-un/Oca2p-un
Genetic Background: C57BL/6J-Oca2p-un

Allelic Composition: Oca2p-un/Oca2p-un+J
Genetic Background: C57BL/6J-Oca2p-un

Allelic Composition: Oca2p-un+J/Oca2p-un+J
Genetic Background: C57BL/6J-Oca2p-un

Allelic Composition: Oca2p-cas/Oca2p-cas
Genetic Background: M. m. castaneus

Allelic Composition: Oca2p-x/Oca2p-x
Genetic Background: C3H101H-Oca2p-x/H

Allelic Composition: Oca2p-un+2J/Oca2p-un+2J
Genetic Background: C57BL/6J-Oca2p-un

Allelic Composition: Oca2p-un+3J/Oca2p-un+3J
Genetic Background: C57BL/6J-Oca2p-un

Allelic Composition: Oca2p-65H/Oca2p
Genetic Background: involves: C3H/HeH

Allelic Composition: Oca2p-65H/Oca2p-65H
Genetic Background: involves: C3H/HeH

Allelic Composition: Oca2p-66H/Oca2p
Genetic Background: involves: 101/H

 MP:0001384 abnormal pup retrieval "a mother does not retrieve stray pups to the nest or delays retrieving stray pups" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Oca2p-25H/Oca2p-25H
Genetic Background: Not Specified

 MP:0001386 abnormal maternal nurturing "failure of mothers to tend offspring" [J:39801]
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Allelic Composition: Oca2p-s/Oca2p-s
Genetic Background: Not Specified

Allelic Composition: Oca2p-25H/Oca2p-25H
Genetic Background: Not Specified

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-25H/Oca2p-25H
Genetic Background: Not Specified

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
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Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0001516 abnormal motor coordination/ balance "altered ability of an animal to maintain skillful and effective interaction of movements or maintenance of equilibrium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Oca2p-s/Oca2p-s
Genetic Background: Not Specified

Allelic Composition: Oca2p-bs/Oca2p-bs
Genetic Background: Not Specified

 MP:0001552 increased circulating triglyceride level "higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416]
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Allelic Composition: Oca2p-30PUb/Oca2p-30PUb
Genetic Background: Not Specified

 MP:0001559 hyperglycemia "abnormally high concentration of glucose in the blood; generally refers to a pathological state" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Oca2p-30PUb/Oca2p-30PUb
Genetic Background: Not Specified

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Oca2p-cp/Oca2p-cp
Genetic Background: Not Specified

 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
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Allelic Composition: Oca2p-bs/Oca2p-bs
Genetic Background: Not Specified

 MP:0001924 infertility "inability to produce live offspring" [J:47225]
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Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Ttc26hop-hpy/Ttc26hop-hpy,Oca2p-s/Oca2p-s
Genetic Background: Not Specified

Allelic Composition: Oca2p-s/Oca2p-s
Genetic Background: Not Specified

Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-103G/Oca2p-103G
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-12DTR/Oca2p-12DTR
Genetic Background: involves: 101/Rl * C3H/Rl

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
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Allelic Composition: Oca2p-12DTR/Oca2p-12DTR
Genetic Background: involves: 101/Rl * C3H/Rl

 MP:0001929 abnormal gametogenesis "defective formation or differentiation of germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:42324]
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Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0001931 abnormal oogenesis "atypical formation or failure to form the female germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
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Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0001932 abnormal spermiogenesis "failure of sperm cells to form or differentiate" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ttc26hop-hpy/Ttc26hop-hpy,Oca2p-s/Oca2p-s
Genetic Background: Not Specified

Allelic Composition: Oca2p-s/Oca2p-s
Genetic Background: Not Specified

Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-bs/Oca2p-bs
Genetic Background: Not Specified

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Otcspf-ash/Y
Genetic Background: B6EiC3Sn a/A-Otcspf-ash/J

 MP:0001940 testicular hypoplasia "decreased cell number in the testicles" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-25H/Oca2p-25H
Genetic Background: Not Specified

 MP:0002058 neonatal lethality "death of animal within one day after birth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Oca2p-4THO-II/Oca2p-4THO-II
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-4THO-II/Oca2p-8FDFoD
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-226THO-I/Oca2p-4THO-II
Genetic Background: involves: 101/Rl * C3H/Rl

 MP:0002066 abnormal motor capabilities/coordination/movement "altered ability to coordinate voluntary movement or repetitive, compulsive movements" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Crb1tm1Wij/Crb1tm2Wij
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002075 abnormal coat color "irregular or unusual pigmentation pattern of the hair in relation to control animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Oca2p/Oca2p,Tyrc-i/Tyrc-i
Genetic Background: involves: STOCK Tyrc-r

Allelic Composition: Oca2p-un/Oca2p-un
Genetic Background: C57BL/6J-Oca2p-un

Allelic Composition: Oca2p-cas/Oca2p-cas
Genetic Background: M. m. castaneus

Allelic Composition: a/a,Oca2p/Oca2p
Genetic Background: Not Specified

Allelic Composition: Oca2p/Oca2p-80K
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p/Oca2p-8FDFoD
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p/Oca2p-116G
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-55H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-61H/Oca2p
Genetic Background: involves: 101/H

Allelic Composition: Oca2p-66H/Oca2p
Genetic Background: involves: 101/H

Allelic Composition: Oca2p-66H/Oca2p-66H
Genetic Background: involves: 101/H

Allelic Composition: Oca2p-80H/Oca2p
Genetic Background: involves: C3H/HeH

Allelic Composition: Oca2p-80H/Oca2p-80H
Genetic Background: involves: C3H/HeH

Allelic Composition: Oca2p-83H/Oca2p
Genetic Background: involves: C3H/HeH

Allelic Composition: Oca2p-85H/Oca2p
Genetic Background: involves: C3H/HeH

Allelic Composition: Oca2p-85H/Oca2p-85H
Genetic Background: involves: C3H/HeH

Allelic Composition: Oca2p-91H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-92H/Oca2p-92H
Genetic Background: involves: 101/H

Allelic Composition: Oca2p-93H/Oca2p
Genetic Background: involves: 101/H

Allelic Composition: Oca2p-95H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-98H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-87H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-88H/Oca2p
Genetic Background: involves: 101/H

Allelic Composition: Oca2p-d/Oca2p-d
Genetic Background: Not Specified

 MP:0002078 abnormal glucose homeostasis "anomaly in the state of equilibrium or processing in the body with respect to glucose in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Oca2p-30PUb/Oca2p-30PUb
Genetic Background: Not Specified

 MP:0002079 increased circulating insulin level "greater than normal levels of insulin in blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Oca2p-30PUb/Oca2p-30PUb
Genetic Background: Not Specified

 MP:0002080 prenatal lethality "death anytime between fertilization and E18.5" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Oca2p-dn/Oca2p-dn
Genetic Background: Not Specified

Allelic Composition: Oca2p-132G/Oca2p-132G
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-96H/Oca2p-96H
Genetic Background: involves: 101/H

Allelic Composition: Oca2p-81H/Oca2p-81H
Genetic Background: involves: C3H/HeH

Allelic Composition: Oca2p-82H/Oca2p-82H
Genetic Background: involves: C3H/HeH

Allelic Composition: Oca2p-87H/Oca2p-87H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0002081 perinatal lethality "death anytime between E18.5 and postnatal day 1 " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Oca2p-4THO-II/Oca2p-4THO-II
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-48PB/Oca2p-48PB
Genetic Background: involves: 101/Rl * C3H/Rl

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Oca2p-132G/Oca2p-132G
Genetic Background: involves: 101/Rl * C3H/Rl

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ttc26hop-hpy/Ttc26hop-hpy,Oca2p-s/Oca2p-s
Genetic Background: Not Specified

Allelic Composition: Oca2p-s/Oca2p-s
Genetic Background: Not Specified

Allelic Composition: Oca2p-103G/Oca2p-103G
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-12DTR/Oca2p-12DTR
Genetic Background: involves: 101/Rl * C3H/Rl

 MP:0002089 abnormal postnatal growth/weight/body size "increased or decreased average body size, weight or growth characteristic abnormalities manifesting after birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Oca2p-bs/Oca2p-bs
Genetic Background: Not Specified

 MP:0002118 abnormal lipid homeostasis "anomaly in the state of equilibrium in the body with respect to lipids in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Oca2p-30PUb/Oca2p-30PUb
Genetic Background: Not Specified

 MP:0002161 abnormal fertility/fecundity "reduced ability or inability to produce live offspring" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Oca2p-bs/Oca2p-bs
Genetic Background: Not Specified

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Oca2p-61H/Oca2p
Genetic Background: involves: 101/H

Allelic Composition: Oca2p-78H/Oca2p-78H
Genetic Background: involves: C3H/HeH

Allelic Composition: Oca2p-92H/Oca2p
Genetic Background: involves: 101/H

Allelic Composition: Oca2p-95H/Oca2p-95H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-97H/Oca2p-97H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0002412 increased susceptibility to bacterial infection "greater likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Oca2p-3Btlr/Oca2p-3Btlr
Genetic Background: C57BL/6J-Oca2p-3Btlr

Allelic Composition: Oca2p-4Btlr/Oca2p-4Btlr
Genetic Background: C57BL/6J-Oca2p-4Btlr

 MP:0002628 fatty liver "an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Oca2p-30PUb/Oca2p-30PUb
Genetic Background: Not Specified

 MP:0002981 increased liver weight "a greater than average weight of the bile-secreting exocrine gland" [il:Ira Lu , Mouse Genome Informatics Curator]
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Allelic Composition: Htr1atm1Tct/Htr1a+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Oca2p-30PUb/Oca2p-x
Genetic Background: Not Specified

 MP:0003136 yellow coat color "amount and distribution of yellow pigment (phaeomelanin) relative to black or brown pigment (eumelanin) is increased compared to wild-type agouti" [llw2:Linda L. Washburn, Mouse Genome Informatics Curator]
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Allelic Composition: Oca2p-cas/Oca2p-cas
Genetic Background: M. m. castaneus

 MP:0003171 phenotypic reversion "reverse mutation to wild-type phenotype from a previously characterized mutant phenotype" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Oca2p-un/Oca2p-un+J
Genetic Background: C57BL/6J-Oca2p-un

Allelic Composition: Oca2p-un+J/Oca2p-un+J
Genetic Background: C57BL/6J-Oca2p-un

Allelic Composition: Oca2p-un+2J/Oca2p-un+2J
Genetic Background: C57BL/6J-Oca2p-un

Allelic Composition: Oca2p-un+3J/Oca2p-un+3J
Genetic Background: C57BL/6J-Oca2p-un

Allelic Composition: Oca2p-un+4J/Oca2p-un+4J
Genetic Background: C57BL/6J-Oca2p-un

Allelic Composition: Oca2p-un+5J/Oca2p-un+5J
Genetic Background: C57BL/6J-Oca2p-un

Allelic Composition: Oca2p-un+6J/Oca2p-un+6J
Genetic Background: C57BL/6J-Oca2p-un

 MP:0003492 abnormal involuntary movement "anomalies in movements that occur independent of planning (eg. reflexive behavior)" [Nmice:Neuromice Consortium Submission]
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Allelic Composition: Oca2p-12DTR/Oca2p-12DTR
Genetic Background: involves: 101/Rl * C3H/Rl

 MP:0003917 increased kidney weight "greater heft of the organs responsible for urine secretion" [RGD:Rat Genome Database submission]
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Allelic Composition: Htr1atm1Tct/Htr1a+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Oca2p-30PUb/Oca2p-x
Genetic Background: Not Specified

 MP:0004381 abnormal hair follicle melanocyte morphology "any structural anomaly of the cells that produce pigment in the hair follicles" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: a/a,Oca2p/Oca2p
Genetic Background: Not Specified

 MP:0004901 decreased male germ cell number "reduced numbers of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-25H/Oca2p-25H
Genetic Background: Not Specified

 MP:0004952 increased spleen weight "greater than average weight of the organ that functions to filter blood and to store red corpuscles and platelets" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Htr1atm1Tct/Htr1a+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Oca2p-30PUb/Oca2p-x
Genetic Background: Not Specified

 MP:0005072 abnormal hair follicle melanin granule "anomalous pigment paricles in the hair follicles" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: a/a,Oca2p/Oca2p
Genetic Background: Not Specified

 MP:0005075 abnormal melanosome morphology "anomalous structure of these tissue-specific cytoplasmic organelles within which melanin pigments are synthesized and stored" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:5346]
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Allelic Composition: Sox11tm1Weg/Sox11tm1Weg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: a/a,Lystbg/Lystbg,Oca2p-J/Oca2p-J
Genetic Background: involves: C3H/HeJ * C3H/Rl * C57BL/6J

 MP:0005077 abnormal melanogenesis "failure of or anomaly in the biosynthetic pathway of melanin formation in cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:5346]
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Allelic Composition: a/a,Oca2p-J/Oca2p-J
Genetic Background: involves: C3H/HeJ

 MP:0005114 premature hair loss "release of fur at an earlier than expected time" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Lystbg-slt/Lystbg-slt,Myo5ad/Myo5ad,Oca2p/Oca2p,Tyrp1b/Tyrp1b
Genetic Background: involves: CT/Ch * YZ57/Ch

 MP:0005172 lack of eye pigmentation "visual organs are devoid of coloring pigment in relation to control animals, usually resulting in a red or pink color" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500]
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Allelic Composition: Oca2p-s/Oca2p-s
Genetic Background: Not Specified

Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-dn/Oca2p-dn
Genetic Background: Not Specified

Allelic Composition: Oca2p-81H/Oca2p-81H
Genetic Background: Not Specified

Allelic Composition: Oca2p-cp/Oca2p-cp
Genetic Background: Not Specified

Allelic Composition: Oca2p-J/Oca2p-J
Genetic Background: C3H/HeJ-Oca2p-J/J

Allelic Composition: Oca2p-un/Oca2p-un+J
Genetic Background: C57BL/6J-Oca2p-un

Allelic Composition: Oca2p-un+J/Oca2p-un+J
Genetic Background: C57BL/6J-Oca2p-un

Allelic Composition: Oca2p-12DTR/Oca2p
Genetic Background: Not Specified

Allelic Composition: Oca2p-9J/Oca2p-9J
Genetic Background: B10.A-H2h2/(2R)SgSnJ

Allelic Composition: Oca2p/Oca2p
Genetic Background: Not Specified

Allelic Composition: a/a,Oca2p/Oca2p
Genetic Background: Not Specified

Allelic Composition: Oca2p-25H/Oca2p-25H
Genetic Background: Not Specified

Allelic Composition: Oca2p-un+2J/Oca2p-un+2J
Genetic Background: C57BL/6J-Oca2p-un

Allelic Composition: Oca2p-un+3J/Oca2p-un+3J
Genetic Background: C57BL/6J-Oca2p-un

Allelic Composition: Oca2p-15J/Oca2p-15J
Genetic Background: C57BL/6

Allelic Composition: Oca2p-18J/Oca2p-18J
Genetic Background: B10.Cg-H2r H2-T18b Oca2p-18J/GrsrJ

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-87H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-88H/Oca2p
Genetic Background: involves: 101/H

Allelic Composition: Oca2p-d/Oca2p-d
Genetic Background: Not Specified

Allelic Composition: Oca2p-5Btlr/Oca2p-5Btlr
Genetic Background: C57BL/6J-Oca2p-5Btlr

Allelic Composition: Oca2p-6Btlr/Oca2p-6Btlr
Genetic Background: C57BL/6J-Oca2p-6Btlr

Allelic Composition: Oca2p-7Btlr/Oca2p-7Btlr
Genetic Background: C57BL/6J-Oca2p-7Btlr

 MP:0005178 increased total circulating cholesterol level "greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Oca2p-30PUb/Oca2p-30PUb
Genetic Background: Not Specified

 MP:0005366 variegated coat color "dappled coloration of the fur; mosaic" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Oca2p-un/Oca2p-un+J
Genetic Background: C57BL/6J-Oca2p-un

Allelic Composition: Oca2p-un+J/Oca2p-un+J
Genetic Background: C57BL/6J-Oca2p-un

Allelic Composition: Oca2p-un+2J/Oca2p-un+2J
Genetic Background: C57BL/6J-Oca2p-un

Allelic Composition: Oca2p-un+3J/Oca2p-un+3J
Genetic Background: C57BL/6J-Oca2p-un

 MP:0005409 darkened coat color "amount and distribution of yellow pigment (phaeomelanin) relative to black or brown pigment (eumelanin) is decreasesd when compared to wild-type agouti" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Oca2p-7R/Oca2p-7R
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p/Oca2p-7R
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-103G/Oca2p-103G
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p/Oca2p-103G
Genetic Background: involves: 101/Rl * C3H/Rl

 MP:0005424 jerky movement "continuous, abrupt, faltering motions of the whole body or a portion of the body" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Oca2p-cp/Oca2p-cp
Genetic Background: Not Specified

Allelic Composition: Oca2p-bs/Oca2p-bs
Genetic Background: Not Specified

 MP:0005578 teratozoospermia "presence of malformed spermatozoa in the semen; malformations include the physical bending of the sperm to produce kinks or bends" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator]
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Allelic Composition: Ttc26hop-hpy/Ttc26hop-hpy,Oca2p-s/Oca2p-s
Genetic Background: Not Specified

Allelic Composition: Oca2p-s/Oca2p-s
Genetic Background: Not Specified

 MP:0006159 ocular albinism "absence of melanin production in the eye only" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Oca2p-Btlr/Oca2p-Btlr
Genetic Background: C57BL/6J-Oca2p-Btlr

Allelic Composition: Oca2p-2Btlr/Oca2p-2Btlr
Genetic Background: C57BL/6J-Oca2p-2Btlr

Allelic Composition: Oca2p-3Btlr/Oca2p-3Btlr
Genetic Background: C57BL/6J-Oca2p-3Btlr

Allelic Composition: Oca2p-4Btlr/Oca2p-4Btlr
Genetic Background: C57BL/6J-Oca2p-4Btlr

 MP:0006380 abnormal spermatid morphology "anomaly in the number or structure of the male germ cells that without further cell division give rise to mature spermatozoa" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-25H/Oca2p-25H
Genetic Background: Not Specified

 MP:0008480 absent eye pigmentation "absence of melanin (pigment) in the eye either due to absent melanocytes or failure of melanin synthesis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Oca2p/Oca2p-80K
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p/Oca2p-8FDFoD
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p/Oca2p-116G
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-116G/Oca2p-116G
Genetic Background: involves: 101/Rl * C3H/Rl

 MP:0008892 abnormal sperm flagellum "any strucutral anomaly of the whiplike posterior filiform portion of the spermatozoon that provides sperm motility" [MESH:A05.360.490.890.840]
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Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-25H/Oca2p-25H
Genetic Background: Not Specified

 MP:0008898 abnormal acrosome morphology "any structural anomaly of the cap-like structure at the anterior end of the sperm head that produces enzymes needed for egg penetration" [MESH:A05.360.490.890.820.100]
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Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-25H/Oca2p-25H
Genetic Background: Not Specified

 MP:0008908 increased total fat pad weight "greater than average weight of the fat pads" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Htr1atm1Tct/Htr1a+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Oca2p-30PUb/Oca2p-x
Genetic Background: Not Specified

 MP:0008912 nervous "increased, skittish, behavior induced by stimulation such as handling, touching or noise" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-103G/Oca2p-103G
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-25H/Oca2p-25H
Genetic Background: Not Specified

 MP:0009230 abnormal sperm head morphology "any structural abnormality of the head segment of the sperm cell which contains the nucleus with densely coiled chromatin fibers, and is surrounded anteriorly by the acrosome which contains enzymes used for penetrating the female egg" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-25H/Oca2p-25H
Genetic Background: Not Specified

 MP:0009233 enlarged sperm head "increased size of the head segment of the sperm cell" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-25H/Oca2p-25H
Genetic Background: Not Specified

 MP:0009554 abnormal hair follicle melanin granule shape "the form of pigment polymers in the hair follicle differs compared to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: a/a,Oca2p/Oca2p
Genetic Background: Not Specified

 MP:0009555 abnormal hair follicle melanin granule distribution "anomaly in the spatial arrangement of particles produced by melanocytes that confer color in the hair follicle" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: a/a,Oca2p/Oca2p
Genetic Background: Not Specified

 MP:0010193 abnormal choroid melanin granule morphology "any structural anomaly of the pigment particles in the choroid" [ISBN-13:978-1-4051-2034-0 "The Pigmentary System, Second Edition"]
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Allelic Composition: a/a,Oca2p-J/Oca2p-J
Genetic Background: involves: C3H/HeJ

Allelic Composition: a/a,Lystbg/Lystbg,Oca2p-J/Oca2p-J
Genetic Background: involves: C3H/HeJ * C3H/Rl * C57BL/6J

 MP:0010389 mosaic coat color "a random coat color pattern due to genetically different populations of cells in the skin e.g. as the result of X-inactivation" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Oca2p-un/Oca2p-un
Genetic Background: C57BL/6J-Oca2p-un

 MP:0010766 abnormal NK cell physiology "any functional anomaly of a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors, and also regulate immune responses via cytokine release and direct contact with other cells" [GOC:add, ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:15771571]
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Allelic Composition: Oca2p-3Btlr/Oca2p-3Btlr
Genetic Background: C57BL/6J-Oca2p-3Btlr

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Oca2p-116G/Oca2p-116G
Genetic Background: involves: 101/Rl * C3H/Rl

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Ttc26hop-hpy/Ttc26hop-hpy,Oca2p-s/Oca2p-s
Genetic Background: Not Specified

Allelic Composition: Oca2p-7FR60Lb/Oca2p-7FR60Lb
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-12R250M/Oca2p-12R250M
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-9DTW/Oca2p-9DTW
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-39DSD/Oca2p-39DSD
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-18CoS/Oca2p-18CoS
Genetic Background: involves: 101/Rl * C3H/Rl

 MP:0011088 partial neonatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: Oca2p-7FR60Lb/Oca2p-7FR60Lb
Genetic Background: involves: 101/Rl * C3H/Rl

 MP:0011090 partial perinatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Oca2p-cp/Oca2p-cp
Genetic Background: Not Specified

 MP:0011091 complete prenatal lethality "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Htr1atm1Tct/Htr1a+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Oca2p-30PUb/Oca2p-30PUb
Genetic Background: Not Specified

Allelic Composition: Oca2p-80K/Oca2p-80K
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-8FDFoD/Oca2p-8FDFoD
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Oca2p-55H/Oca2p-55H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-93H/Oca2p-93H
Genetic Background: involves: 101/H

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Oca2p-12DTR/Oca2p-12DTR
Genetic Background: involves: 101/Rl * C3H/Rl

 MP:0011277 decreased tail pigmentation "visually detectable dilution of pigment present on the tail surface" [MGI:csmith]
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Allelic Composition: a/a,Oca2p/Oca2p
Genetic Background: Not Specified

Allelic Composition: Oca2p-66H/Oca2p
Genetic Background: involves: 101/H

 MP:0011279 decreased ear pigmentation "visually detectable dilution of pigment present in the outer ear" [MGI:csmith]
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Allelic Composition: Oca2p-x/Oca2p-x
Genetic Background: C3H101H-Oca2p-x/H

Allelic Composition: a/a,Oca2p/Oca2p
Genetic Background: Not Specified

 MP:0011400 complete lethality "all individuals of a given genotype in a population die before the end of the normal lifespan but time(s) of death are unspecified" [MGI:llw2]
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Allelic Composition: Oca2p-98H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-99H/Oca2p-99H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0011627 decreased skin pigmentation "visually detectable dilution of pigment present in the skin" [MGI:csmith]
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Allelic Composition: a/a,Oca2p/Oca2p
Genetic Background: Not Specified

 MP:0020550 multinucleated giant male germ cells "presence of large cells containing multiple nuclei formed abnormal opening of the cytoplasmic bridges that are part of normal germ cell division" [PMID:16272280, url:https://ntp.niehs.nih.gov/nnl/male_reproductive/testis/setubmgcel/index.htm]
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Allelic Composition: Oca2p-6H/Oca2p-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Oca2p-25H/Oca2p-25H
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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