ENSMUSG00000030651


Mus musculus

Features
Gene ID: ENSMUSG00000030651
  
Biological name :Art2b
  
Synonyms : Art2b / O35975 / T-cell ecto-ADP-ribosyltransferase 2
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: E2
Gene start: 101576970
Gene end: 101585600
  
Corresponding Affymetrix probe sets: 10565994 (MoGene1.0st)   1420794_at (Mouse Genome 430 2.0 Array)   1446814_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000065658
Ensembl peptide - ENSMUSP00000147267
NCBI entrez gene - 11872     See in Manteia.
MGI - MGI:107545
RefSeq - XM_017321951
RefSeq - NM_019915
RefSeq - XM_006507256
RefSeq Peptide - NP_064299
swissprot - O35975
swissprot - A0A1B0GQV6
Ensembl - ENSMUSG00000030651
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 art4ENSDARG00000078178Danio rerio
 BX908804.1ENSDARG00000002797Danio rerio
 BX908804.3ENSDARG00000117123Danio rerio
 CABZ01019904.1ENSDARG00000104193Danio rerio
 FO904885.1ENSDARG00000109683Danio rerio
 FO904885.2ENSDARG00000114377Danio rerio
 FO907110.1ENSDARG00000100364Danio rerio
 si:ch211-145b13.6ENSDARG00000069998Danio rerio
 si:ch211-163m16.7ENSDARG00000079185Danio rerio
 si:ch211-51i16.1ENSDARG00000111323Danio rerio
 si:ch211-51i16.3ENSDARG00000105044Danio rerio
 si:ch73-379f5.5ENSDARG00000094959Danio rerio
 zmp:0000000997ENSDARG00000090501Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Art2a-psENSMUSG0000009251777
Art1 / Q60935 / ADP-ribosyltransferase 1 / P52961*ENSMUSG0000003099635
Art5 / P70352 / ADP-ribosyltransferase 5 / Q96L15*ENSMUSG0000007042435
Art3 / Q8R2G4 / ADP-ribosyltransferase 3 / Q13508*ENSMUSG0000003484230
Art4 / Q9CRA0 / Ecto-ADP-ribosyltransferase 4 / Q93070* / ADP-ribosyltransferase 4 (Dombrock blood group)*ENSMUSG0000003021727


Protein motifs (from Interpro)
Interpro ID Name
 IPR000768  NAD:arginine ADP-ribosyltransferase, ART


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006471 protein ADP-ribosylation IEA
 biological_processGO:0018120 peptidyl-arginine ADP-ribosylation IDA
 biological_processGO:0019677 NAD catabolic process IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0019897 extrinsic component of plasma membrane TAS
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0031362 anchored component of external side of plasma membrane IDA
 molecular_functionGO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity IDA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IDA
 molecular_functionGO:0061810 NAD glycohydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004804 decreased susceptibility to autoimmune diabetes "reduced likelihood that an organism will develop inflammatory pancreatic disease resulting from the body attacking and destroying the insulin-producing beta islet cells of the pancreas" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gata6tm2Msp/Gata6tm2Msp,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

 MP:0006414 decreased T cell apoptosis "decrease in the number of T cells undergoing programmed cell death" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Apoa1tm1Unc/Apoa1tm1Unc
Genetic Background: B6.129P2-Apoa1tm1Unc/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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