ENSMUSG00000030685


Mus musculus

Features
Gene ID: ENSMUSG00000030685
  
Biological name :Kctd13
  
Synonyms : Kctd13 / potassium channel tetramerisation domain containing 13 / Q8BGV7
  
Possible biological names infered from orthology : potassium channel tetramerization domain containing 13 / Q8WZ19
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: F3
Gene start: 126928879
Gene end: 126945631
  
Corresponding Affymetrix probe sets: 10557528 (MoGene1.0st)   1434154_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000032924
NCBI entrez gene - 233877     See in Manteia.
MGI - MGI:1923739
RefSeq - XM_006507736
RefSeq - NM_172747
RefSeq - XM_006507735
RefSeq Peptide - NP_766335
swissprot - Q8BGV7
Ensembl - ENSMUSG00000030685
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A9ULR9ENSDARG00000044769Danio rerio
 KCTD13ENSG00000174943Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kctd10 / Q922M3 / potassium channel tetramerisation domain containing 10ENSMUSG0000000109864
O70479 / Tnfaip1 / tumor necrosis factor, alpha-induced protein 1 (endothelial) / Q13829* / TNF alpha induced protein 1*ENSMUSG0000001761561
Kctd14 / Q9BQ13* / potassium channel tetramerization domain containing 14*ENSMUSG0000005172718
Kctd7 / Q8BJK1 / BTB/POZ domain-containing protein KCTD7 / Q96MP8* / potassium channel tetramerization domain containing 7*ENSMUSG0000003411017


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR003131  Potassium channel tetramerisation-type BTB domain
 IPR011333  SKP1/BTB/POZ domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0016567 protein ubiquitination ISO
 biological_processGO:0035024 negative regulation of Rho protein signal transduction IEA
 biological_processGO:0043149 stress fiber assembly IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0045740 positive regulation of DNA replication IEA
 biological_processGO:0050806 positive regulation of synaptic transmission IMP
 biological_processGO:0051260 protein homooligomerization IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017049 GTP-Rho binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
Show

Allelic Composition: Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi,Krt14tm1(cre)Wbm/Krt14+
Genetic Background: B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm

Allelic Composition: Kctd13tm1.1(KOMP)Vlcg/Kctd13tm1.1(KOMP)Vlcg
Genetic Background: involves: C57BL/6J * C57BL/6NTac

 MP:0002206 abnormal CNS synaptic transmission "defect in the communication from a neuron to a target across a synapse in the central nervous system" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi,Krt14tm1(cre)Wbm/Krt14+
Genetic Background: B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm

Allelic Composition: Kctd13tm1.1(KOMP)Vlcg/Kctd13tm1.1(KOMP)Vlcg
Genetic Background: involves: C57BL/6J * C57BL/6NTac

 MP:0002912 abnormal excitatory postsynaptic potential "defect in the potential detected in postsynaptic cells when an excitatory impulse arrives at the synapse causing depolarization" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi,Krt14tm1(cre)Wbm/Krt14+
Genetic Background: B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm

Allelic Composition: Kctd13tm1.1(KOMP)Vlcg/Kctd13tm1.1(KOMP)Vlcg
Genetic Background: involves: C57BL/6J * C57BL/6NTac

 MP:0004753 abnormal miniature excitatory postsynaptic currents "defect in the size or duration of spontaneous currents detected in postsynaptic cells that occur in the absence of an excitatory impulse" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi,Krt14tm1(cre)Wbm/Krt14+
Genetic Background: B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm

Allelic Composition: Kctd13tm1.1(KOMP)Vlcg/Kctd13tm1.1(KOMP)Vlcg
Genetic Background: involves: C57BL/6J * C57BL/6NTac

 MP:0009435 abnormal miniature inhibitory postsynaptic currents "defect in the size or duration of spontaneous currents detected in postsynaptic cells that occur in the absence of an inhibitory impulse" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi,Krt14tm1(cre)Wbm/Krt14+
Genetic Background: B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm

Allelic Composition: Kctd13tm1.1(KOMP)Vlcg/Kctd13tm1.1(KOMP)Vlcg
Genetic Background: involves: C57BL/6J * C57BL/6NTac

 MP:0020338 abnormal hippocampal pyramidal neuron dendrite morphology "structural anomaly of the highly branched tree-like process of the hippocampal neurons that have a pyramid-shaped soma with the apex and an apical dendrite pointed toward the pial surface and other dendrites and an axon emerging from the base" [CL_1001571, ORCID: orcid.org/0000-0003-4606-0597]
Show

Allelic Composition: Kctd13tm1.1(KOMP)Vlcg/Kctd13tm1.1(KOMP)Vlcg
Genetic Background: involves: C57BL/6J * C57BL/6NTac

 MP:0020357 abnormal excitatory synapse morphology "any structural anomaly of a synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell" [GO:0060076]
Show

Allelic Composition: Kctd13tm1.1(KOMP)Vlcg/Kctd13tm1.1(KOMP)Vlcg
Genetic Background: involves: C57BL/6J * C57BL/6NTac

 MP:0020508 decreased dendritic spine density "decrease in the number of dendritic spines in a given cross-sectional area of a dendrite" [MGI:smb]
Show

Allelic Composition: Kctd13tm1.1(KOMP)Vlcg/Kctd13tm1.1(KOMP)Vlcg
Genetic Background: involves: C57BL/6J * C57BL/6NTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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