ENSMUSG00000030792


Mus musculus

Features
Gene ID: ENSMUSG00000030792
  
Biological name :Dkkl1
  
Synonyms : Dickkopf-like protein 1 / Dkkl1 / Q9QZL9
  
Possible biological names infered from orthology : dickkopf like acrosomal protein 1 / Q9UK85
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: B3
Gene start: 45207519
Gene end: 45212147
  
Corresponding Affymetrix probe sets: 10563170 (MoGene1.0st)   1417787_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000033057
Ensembl peptide - ENSMUSP00000147678
Ensembl peptide - ENSMUSP00000147489
NCBI entrez gene - 50722     See in Manteia.
MGI - MGI:1354963
RefSeq - NM_015789
RefSeq - XM_006540985
RefSeq Peptide - NP_056604
swissprot - A0A1B0GRV4
swissprot - Q9QZL9
swissprot - A0A1B0GRE6
Ensembl - ENSMUSG00000030792
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DKKL1ENSG00000104901Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007341 penetration of zona pellucida IMP
 biological_processGO:0043065 positive regulation of apoptotic process IMP
 biological_processGO:0045600 positive regulation of fat cell differentiation IDA
 biological_processGO:2000225 negative regulation of testosterone biosynthetic process IMP
 cellular_componentGO:0001669 acrosomal vesicle IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002673 abnormal sperm count "increased or decreased numbers of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Msx1tm1Rilm/Msx1tm1Rilm
Genetic Background: involves: 129S4/SvJae

 MP:0004543 abnormal sperm physiology "anomaly in the normal function of spermatozoa" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Msx1tm1Rilm/Msx1tm1Rilm
Genetic Background: involves: 129S4/SvJae

 MP:0004851 increased testis weight "greater average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Msx1tm1Rilm/Msx1tm1Rilm
Genetic Background: involves: 129S4/SvJae

 MP:0005410 abnormal fertilization "anomaly in the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Col8a2Aca23/Col8a2Aca23
Genetic Background: C57BL/6J-Col8a2Aca23

 MP:0005411 delayed fertilization "a lag in the normal time of onset of the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Col8a2Aca23/Col8a2Aca23
Genetic Background: C57BL/6J-Col8a2Aca23

 MP:0009647 decreased fertilization frequency "he number of secondary oocytes each penetrated by a spermatozoon followed by fusion of the male and female pronuclei are fewer than expected" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Col8a2Aca23/Col8a2Aca23
Genetic Background: C57BL/6J-Col8a2Aca23

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr