ENSMUSG00000030854
Mus musculus phosphatase Ptpn5 protein-tyrosine protein activity type dephosphorylation membrane increased tyrosine endoplasmic reticulum bone ptp specific phosphatases domain catalytic kim-containing active site receptor r non-receptor phosphatase-like peptidyl-tyrosine cytoplasm integral component phosphotyrosine residue
Features Gene ID: ENSMUSG00000030854 Biological name :Ptpn5 Synonyms : P54830 / / Possible biological names infered from orthology : P54829 / Species: Mus musculus Chr. number: 7 Strand: -1 Band: B3 Gene start: 47077795 Gene end: 47133684 Corresponding Affymetrix probe sets: 10563685 (MoGene1.0st) 1423544_at (Mouse Genome 430 2.0 Array) 1425130_a_at (Mouse Genome 430 2.0 Array) 1425131_at (Mouse Genome 430 2.0 Array) Cross references: Ensembl peptide - ENSMUSP0000003314219259
See in Manteia .
MGI:97807 XM_017322046 NM_001163565 NM_013643 XM_006540713 XM_006540714 XM_006540715 NP_038671 NP_001157037 P54830 ENSMUSG00000030854
See expression report in BioGPS See gene description in Wikigenes See co-cited genes in PubMed Ortholog prediction (from Ensembl )Paralog prediction (from Ensembl ) Ptprr / Q62132 / protein tyrosine phosphatase, receptor type, R / Q15256* ENSMUSG00000020151 43 Ptpn7 / Q8BUM3 / Mus musculus protein tyrosine phosphatase, non-receptor type 7 (Ptpn7), transcript variant 2, mRNA. / P35236* / protein tyrosine phosphatase, non-receptor type 7* ENSMUSG00000031506 32 P35235 / Ptpn11 / Tyrosine-protein phosphatase non-receptor type 11 / Q06124* / protein tyrosine phosphatase, non-receptor type 11* ENSMUSG00000043733 24 Ptpn6 / P29351 / protein tyrosine phosphatase, non-receptor type 6 / P29350* ENSMUSG00000004266 23 Ptprn / protein tyrosine phosphatase, receptor type, N / Q16849* ENSMUSG00000026204 22 P80560 / Ptprn2 / protein tyrosine phosphatase, receptor type, N polypeptide 2 / Q92932* / protein tyrosine phosphatase, receptor type N2* ENSMUSG00000056553 22
Protein motifs (from Interpro ) IPR000242 PTP type protein phosphatase IPR000387 Tyrosine specific protein phosphatases domain IPR003595 Protein-tyrosine phosphatase, catalytic IPR008356 Protein-tyrosine phosphatase, KIM-containing IPR016130 Protein-tyrosine phosphatase, active site IPR016334 Protein-tyrosine phosphatase, receptor type R/non-receptor type 5 IPR029021 Protein-tyrosine phosphatase-like
Gene Ontology (GO ) nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic processnitrogen compound metabolic process cellular metabolic processcellular metabolic process primary metabolic processprimary metabolic process organic substance metabolic processorganic substance metabolic process protein binding catalytic activity, acting on a protein hydrolase activity protein binding catalytic activity, acting on a protein hydrolase activity protein binding catalytic activity, acting on a protein hydrolase activity protein binding catalytic activity, acting on a protein hydrolase activity protein binding catalytic activity, acting on a protein hydrolase activity protein binding catalytic activity, acting on a protein hydrolase activity protein binding catalytic activity, acting on a protein hydrolase activity protein binding catalytic activity, acting on a protein hydrolase activity protein binding catalytic activity, acting on a protein hydrolase activity protein binding catalytic activity, acting on a protein hydrolase activity protein bindingprotein binding catalytic activity, acting on a proteincatalytic activity, acting on a protein hydrolase activityhydrolase activity cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cellcell organelleorganelle membranemembrane
Pathways (from Reactome )No match Phenotype (from MGI , Zfin or HPO ) immune system phenotype hematopoietic system phenotype cardiovascular system phenotype skeleton phenotype nervous system phenotype behavior/neurological phenotype immune system phenotype hematopoietic system phenotype cardiovascular system phenotype skeleton phenotype nervous system phenotype behavior/neurological phenotype immune system phenotype hematopoietic system phenotype cardiovascular system phenotype skeleton phenotype nervous system phenotype behavior/neurological phenotype immune system phenotype hematopoietic system phenotype cardiovascular system phenotype skeleton phenotype nervous system phenotype behavior/neurological phenotype immune system phenotype hematopoietic system phenotype cardiovascular system phenotype skeleton phenotype nervous system phenotype behavior/neurological phenotype immune system phenotype hematopoietic system phenotype cardiovascular system phenotype skeleton phenotype nervous system phenotype behavior/neurological phenotype immune system phenotype hematopoietic system phenotype cardiovascular system phenotype skeleton phenotype nervous system phenotype behavior/neurological phenotype immune system phenotype hematopoietic system phenotype cardiovascular system phenotype skeleton phenotype nervous system phenotype behavior/neurological phenotype immune system phenotype hematopoietic system phenotype cardiovascular system phenotype skeleton phenotype nervous system phenotype behavior/neurological phenotype immune system phenotype hematopoietic system phenotype cardiovascular system phenotype skeleton phenotype nervous system phenotype behavior/neurological phenotype immune system phenotypeimmune system phenotype hematopoietic system phhematopoietic system phenotype cardiovascular system pcardiovascular system phenotype skeleton phenotypeskeleton phenotype nervous system phenotypnervous system phenotype behavior/neurological pbehavior/neurological phenotype MP:0000221 decreased WBC count "fewer than normal numbers of WBCs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Ptpn12tm1b(NCOM)Mfgc /Ptpn12tm1b(NCOM)Mfgc Genetic Background: C57BL/6N-Ptpn12tm1b(NCOM)Mfgc /Tcp
MP:0002833 increased heart weight "greater than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission]
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Allelic Composition: Ptpn12tm1b(NCOM)Mfgc /Ptpn12tm1b(NCOM)Mfgc Genetic Background: C57BL/6N-Ptpn12tm1b(NCOM)Mfgc /Tcp
MP:0003795 abnormal bone structure
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Allelic Composition: Ptpn12tm1b(NCOM)Mfgc /Ptpn12tm1b(NCOM)Mfgc Genetic Background: C57BL/6N-Ptpn12tm1b(NCOM)Mfgc /Tcp
MP:0009141 increased prepulse inhibition "increase in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Ptpn12tm1b(NCOM)Mfgc /Ptpn12tm1b(NCOM)Mfgc Genetic Background: C57BL/6N-Ptpn12tm1b(NCOM)Mfgc /Tcp
MP:0010123 increased bone mineral content "elevation in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ptpn12tm1b(NCOM)Mfgc /Ptpn12tm1b(NCOM)Mfgc Genetic Background: C57BL/6N-Ptpn12tm1b(NCOM)Mfgc /Tcp
MP:0011396 abnormal sleep behavior "any anomaly in the actions, reactions, or performance of an organism during a periodic, readily reversible state of reduced awareness and metabolic activity" [MGI:smb]
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Allelic Composition: Ptpn12tm1b(NCOM)Mfgc /Ptpn12tm1b(NCOM)Mfgc Genetic Background: C57BL/6N-Ptpn12tm1b(NCOM)Mfgc /Tcp
Interacting proteins (from Reactome )No match
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