ENSMUSG00000031170


Mus musculus

Features
Gene ID: ENSMUSG00000031170
  
Biological name :Slc38a5
  
Synonyms : Q3U1J0 / Slc38a5 / Sodium-coupled neutral amino acid transporter 5
  
Possible biological names infered from orthology : Q8WUX1 / solute carrier family 38 member 5
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: A1.1
Gene start: 8271133
Gene end: 8280179
  
Corresponding Affymetrix probe sets: 10598507 (MoGene1.0st)   1454622_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000111254
Ensembl peptide - ENSMUSP00000115713
Ensembl peptide - ENSMUSP00000033512
Ensembl peptide - ENSMUSP00000111253
NCBI entrez gene - 209837     See in Manteia.
MGI - MGI:2148066
RefSeq - NM_172479
RefSeq Peptide - NP_766067
swissprot - A2ALH6
swissprot - Q3U1J0
Ensembl - ENSMUSG00000031170
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc38a5aENSDARG00000009901Danio rerio
 slc38a5bENSDARG00000014587Danio rerio
 Q8WUX1ENSG00000017483Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9DCP2 / Slc38a3 / Sodium-coupled neutral amino acid transporter 3 / Q99624* / solute carrier family 38 member 3*ENSMUSG0000001006459
Q8CFE6 / Slc38a2 / Sodium-coupled neutral amino acid transporter 2 / Q96QD8* / solute carrier family 38 member 2*ENSMUSG0000002246250
Q8R1S9 / Slc38a4 / Mus musculus solute carrier family 38, member 4 (Slc38a4), transcript variant 1, mRNA. / Q969I6* / solute carrier family 38 member 4*ENSMUSG0000002246450
Q8K2P7 / Slc38a1 / Sodium-coupled neutral amino acid transporter 1 / Q9H2H9* / solute carrier family 38 member 1*ENSMUSG0000002316946
G3UVW3 / Slc38a6 / Probable sodium-coupled neutral amino acid transporter 6 / Q8IZM9* / solute carrier family 38 member 6*ENSMUSG0000004471239
Q3USY0 / Slc38a11 / Putative sodium-coupled neutral amino acid transporter 11 / Q08AI6* / solute carrier family 38 member 11*ENSMUSG0000006117122
Q5I012 / Slc38a10 / Putative sodium-coupled neutral amino acid transporter 10 / Q9HBR0* / solute carrier family 38 member 10*ENSMUSG0000006130619


Protein motifs (from Interpro)
Interpro ID Name
 IPR013057  Amino acid transporter, transmembrane domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015816 glycine transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0015187 glycine transmembrane transporter activity IBA


Pathways (from Reactome)
Pathway description
Amino acid transport across the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000189 hypoglycemia "low levels of plasma glucose in the circulating blood; this generally refers to a pathological state" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Gcgrtm1Mjch/Gcgrtm1Mjch,Slc38a5tm1(KOMP)Vlcg/Slc38a5tm1(KOMP)Vlcg
Genetic Background: involves: 129/Sv * C57BL/6 * C57BL/6J * C57BL/6NTac * SJL

 MP:0002712 increased circulating glucagon level "greater than normal blood concentration of this peptide hormone" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Gcgrtm1Mjch/Gcgrtm1Mjch,Slc38a5tm1(KOMP)Vlcg/Slc38a5tm1(KOMP)Vlcg
Genetic Background: involves: 129/Sv * C57BL/6 * C57BL/6J * C57BL/6NTac * SJL

 MP:0002727 decreased circulating insulin level "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gcgrtm1Mjch/Gcgrtm1Mjch,Slc38a5tm1(KOMP)Vlcg/Slc38a5tm1(KOMP)Vlcg
Genetic Background: involves: 129/Sv * C57BL/6 * C57BL/6J * C57BL/6NTac * SJL

 MP:0005216 abnormal pancreatic alpha cell morphology "malformation of the cells of the pancreas that secrete glucagon" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Myo9atm1.2Bah/Myo9atm1.2Bah,Rhobtm1Gcp/Rhobtm1Gcp
Genetic Background: involves: 129/Sv * C57BL/6 * SJL

Allelic Composition: Gcgrtm1Mjch/Gcgrtm1Mjch,Slc38a5tm1(KOMP)Vlcg/Slc38a5tm1(KOMP)Vlcg
Genetic Background: involves: 129/Sv * C57BL/6 * C57BL/6J * C57BL/6NTac * SJL

 MP:0005311 abnormal circulating amino acid level "aberrant concentration in the blood of these organic compounds, which, when polymerized, form proteins" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:83263]
Show

Allelic Composition: Gcgrtm1Mjch/Gcgrtm1Mjch,Slc38a5tm1(KOMP)Vlcg/Slc38a5tm1(KOMP)Vlcg
Genetic Background: involves: 129/Sv * C57BL/6 * C57BL/6J * C57BL/6NTac * SJL

 MP:0005491 islet cell hyperplasia "increased numbers cells within the structures that are scattered throughout the pancreas and comprise its endocrine portion" [J:48446, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Gcgrtm1Mjch/Gcgrtm1Mjch,Slc38a5tm1(KOMP)Vlcg/Slc38a5tm1(KOMP)Vlcg
Genetic Background: involves: 129/Sv * C57BL/6 * C57BL/6J * C57BL/6NTac * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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