ENSMUSG00000031667


Mus musculus

Features
Gene ID: ENSMUSG00000031667
  
Biological name :Aktip
  
Synonyms : Aktip / Mus musculus thymoma viral proto-onco 1 interacting protein (Aktip), transcript variant 6, mRNA. / Q64362
  
Possible biological names infered from orthology : AKT interacting protein / Q9H8T0
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: C4
Gene start: 91111784
Gene end: 91199976
  
Corresponding Affymetrix probe sets: 10580537 (MoGene1.0st)   1423364_a_at (Mouse Genome 430 2.0 Array)   1430219_at (Mouse Genome 430 2.0 Array)   1437767_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000113769
Ensembl peptide - ENSMUSP00000113379
Ensembl peptide - ENSMUSP00000119277
Ensembl peptide - ENSMUSP00000148050
Ensembl peptide - ENSMUSP00000147841
Ensembl peptide - ENSMUSP00000147768
Ensembl peptide - ENSMUSP00000105238
Ensembl peptide - ENSMUSP00000112375
NCBI entrez gene - 14339     See in Manteia.
MGI - MGI:3693832
RefSeq - XM_017312574
RefSeq - NM_001358935
RefSeq - NM_001358936
RefSeq - NM_001358937
RefSeq - NM_001358938
RefSeq - NM_010241
RefSeq - XM_006530669
RefSeq - XM_006530673
RefSeq - XM_011248302
RefSeq - XM_011248303
RefSeq - XM_011248304
RefSeq - XM_011248305
RefSeq - XM_011248306
RefSeq - XM_011248307
RefSeq - XM_017312571
RefSeq - XM_017312572
RefSeq - XM_017312573
RefSeq - NM_001302266
RefSeq - NM_001302267
RefSeq - NM_001302268
RefSeq - NM_001302337
RefSeq - NM_001358934
RefSeq Peptide - NP_001289196
RefSeq Peptide - NP_001345864
RefSeq Peptide - NP_001345865
RefSeq Peptide - NP_001345866
RefSeq Peptide - NP_001345867
RefSeq Peptide - NP_034371
RefSeq Peptide - NP_001289195
RefSeq Peptide - NP_001289197
RefSeq Peptide - NP_001289266
RefSeq Peptide - NP_001345863
swissprot - D3Z2J4
swissprot - A0A1B0GSS3
swissprot - A0A1B0GS90
swissprot - A0A1B0GS26
swissprot - D3Z632
swissprot - Q64362
Ensembl - ENSMUSG00000031667
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aktipENSDARG00000026862Danio rerio
 AKTIPENSGALG00000033378Gallus gallus
 AKTIPENSG00000166971Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000608  Ubiquitin-conjugating enzyme E2
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation ISO
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007032 endosome organization ISS
 biological_processGO:0007040 lysosome organization ISS
 biological_processGO:0008333 endosome to lysosome transport ISO
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0032092 positive regulation of protein binding ISO
 biological_processGO:0045022 early endosome to late endosome transport ISO
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030897 HOPS complex ISO
 cellular_componentGO:0070695 FHF complex ISO
 molecular_functionGO:0031625 ubiquitin protein ligase binding IBA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000063 reduced bone density "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]
Show

Allelic Composition: Adipor1tm1b(EUCOMM)Hmgu/Adipor1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Adipor1tm1b(EUCOMM)Hmgu/H

 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Adipor1tm1b(EUCOMM)Hmgu/Adipor1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Adipor1tm1b(EUCOMM)Hmgu/H

 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Adipor1tm1b(EUCOMM)Hmgu/Adipor1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Adipor1tm1b(EUCOMM)Hmgu/H

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
Show

Allelic Composition: Adipor1tm1b(EUCOMM)Hmgu/Adipor1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Adipor1tm1b(EUCOMM)Hmgu/H

 MP:0002764 short tibia " reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Adipor1tm1b(EUCOMM)Hmgu/Adipor1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Adipor1tm1b(EUCOMM)Hmgu/H

 MP:0003795 abnormal bone structure 
Show

Allelic Composition: Adipor1tm1b(EUCOMM)Hmgu/Adipor1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Adipor1tm1b(EUCOMM)Hmgu/H

 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
Show

Allelic Composition: Adipor1tm1b(EUCOMM)Hmgu/Adipor1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Adipor1tm1b(EUCOMM)Hmgu/H

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Adipor1tm1b(EUCOMM)Hmgu/Adipor1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Adipor1tm1b(EUCOMM)Hmgu/H

 MP:0010124 decreased bone mineral content "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Adipor1tm1b(EUCOMM)Hmgu/Adipor1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Adipor1tm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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