ENSMUSG00000031932


Mus musculus

Features
Gene ID: ENSMUSG00000031932
  
Biological name :Gpr83
  
Synonyms : Gpr83 / P30731 / Probable G-protein coupled receptor 83
  
Possible biological names infered from orthology : G protein-coupled receptor 83 / Q9NYM4
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: A2
Gene start: 14860210
Gene end: 14870789
  
Corresponding Affymetrix probe sets: 10583286 (MoGene1.0st)   1423415_at (Mouse Genome 430 2.0 Array)   1439569_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034408
Ensembl peptide - ENSMUSP00000111287
NCBI entrez gene - 14608     See in Manteia.
MGI - MGI:95712
RefSeq - XM_006510017
RefSeq - NM_001310734
RefSeq - NM_010287
RefSeq Peptide - NP_034417
RefSeq Peptide - NP_001297663
swissprot - P30731
swissprot - Q542Q9
swissprot - Q544C4
Ensembl - ENSMUSG00000031932
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GPR83ENSGALG00000017212Gallus gallus
 GPR83ENSG00000123901Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pgr15lENSMUSG0000003121242
Gpr165ENSMUSG0000003121036
Tacr3 / P47937 / tachykinin receptor 3 / P29371*ENSMUSG0000002817227
Prlhr / Q6VMN6 / Prolactin-releasing peptide receptor / P49683* / prolactin releasing hormone receptor*ENSMUSG0000004505226
Tacr2 / P30549 / tachykinin receptor 2 / P21452*ENSMUSG0000002008125
Tacr1 / P30548 / tachykinin receptor 1 / P25103*ENSMUSG0000003004325
Npy2r / P97295 / Neuropeptide Y receptor type 2 / P49146* / neuropeptide Y receptor Y2*ENSMUSG0000002800424
Npy1r / Q04573 / Mus musculus neuropeptide Y receptor Y1 (Npy1r), transcript variant 2, mRNA. / P25929* / neuropeptide Y receptor Y1*ENSMUSG0000003643724
Npy4r / Q61041 / Neuropeptide Y receptor type 4 / NPY4R2* / P50391* / neuropeptide Y receptor Y4* / neuropeptide Y receptor Y4-2*ENSMUSG0000004833722
Npy6r / Q61212 / Neuropeptide Y receptor type 6 ENSMUSG0000003807120
Npy5r / O70342 / Mus musculus neuropeptide Y receptor Y5 (Npy5r), transcript variant 2, mRNA. / Q15761* / neuropeptide Y receptor Y5*ENSMUSG0000004401419
Prokr1 / Q9JKL1 / Mus musculus prokineticin receptor 1 (Prokr1), transcript variant 2, mRNA. / Q8TCW9* / prokineticin receptor 1*ENSMUSG0000004940918
Prokr2 / Q8K458 / Prokineticin receptor 2 / Q8NFJ6*ENSMUSG0000005055817


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000611  Neuropeptide Y receptor family
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0051384 response to glucocorticoid IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0097730 non-motile cilium IDA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004983 neuropeptide Y receptor activity IEA


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000693 spleen hyperplasia "increased cell number in the spleen" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33401]
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Allelic Composition: Nek1kat/Nek1kat
Genetic Background: involves: C3HeB/FeJLe * RBF/Dn

 MP:0001364 decreased anxiety-related response "when compared to controls, subjects exhibit fewer responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:86626, J:85438, J:64043]
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Allelic Composition: Taok2tm1.2Dkap/Taok2tm1.2Dkap
Genetic Background: B6(Cg)-Taok2tm1.2Dkap

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
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Allelic Composition: Taok2tm1.2Dkap/Taok2tm1.2Dkap
Genetic Background: B6(Cg)-Taok2tm1.2Dkap

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Hephsla/Y
Genetic Background: B6.Cg-Hephsla

 MP:0008075 decreased CD4-positive T cell number "reduced number of the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Nek1kat/Nek1kat
Genetic Background: involves: C3HeB/FeJLe * RBF/Dn

 MP:0011976 sweet preference "subjects demonstrate predilection for sweet tasting substances over other offered substance" [MGI:csmith]
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Allelic Composition: Taok2tm1.2Dkap/Taok2tm1.2Dkap
Genetic Background: B6(Cg)-Taok2tm1.2Dkap

 MP:0012307 impaired spatial learning "impaired ability to ascertain or acquire spatial location information in order to improve navigation or other behavior using such location cues" [MGI:csmith]
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Allelic Composition: Taok2tm1.2Dkap/Taok2tm1.2Dkap
Genetic Background: B6(Cg)-Taok2tm1.2Dkap

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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