ENSMUSG00000032174


Mus musculus

Features
Gene ID: ENSMUSG00000032174
  
Biological name :Icam5
  
Synonyms : Icam5 / Intercellular adhesion molecule 5 / Q60625
  
Possible biological names infered from orthology : Q9UMF0
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: A3
Gene start: 21032073
Gene end: 21039036
  
Corresponding Affymetrix probe sets: 10583535 (MoGene1.0st)   1418619_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000019616
NCBI entrez gene - 15898     See in Manteia.
MGI - MGI:109430
RefSeq - NM_008319
RefSeq Peptide - NP_032345
swissprot - Q60625
Ensembl - ENSMUSG00000032174
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ICAM5ENSG00000105376Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Icam1 / P13597 / intercellular adhesion molecule 1 / P05362*ENSMUSG0000003740523
Tcam1 / testicular cell adhesion molecule 1ENSMUSG0000002071221
Icam4 / Q9ERM2 / Intercellular adhesion molecule 4 / Q14773* / intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)*ENSMUSG000000010149
Icam2 / P35330 / Intercellular adhesion molecule 2 / P13598*ENSMUSG000000010298


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003987  Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal
 IPR003988  Intercellular adhesion molecule
 IPR007110  Immunoglobulin-like domain
 IPR013768  Intercellular adhesion molecule, N-terminal
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006909 phagocytosis IDA
 biological_processGO:0007155 cell adhesion IBA
 biological_processGO:0098609 cell-cell adhesion IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005178 integrin binding IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Integrin cell surface interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002063 abnormal learning/memory/conditioning "altered ability to receive, store or recall informational stimuli" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Krt71Rgsc689/?
Genetic Background: involves: C57BL/6J * DBA/2J

 MP:0002634 abnormal sensorimotor gating "malfunction of the process by which inhibitory neural pathways filter multiple stimuli and allow attention to be focused on one stimulus; usually measured by pre-pulse inhibition (PPI)" [J:42758, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Krt71Rgsc689/?
Genetic Background: involves: C57BL/6J * DBA/2J

 MP:0003008 enhanced long term potentiation "greater than the normal persistent robust synaptic response induced by synchronous stimulation of pre- and postsynaptic cells " [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3, J:81922]
Show

Allelic Composition: Krt71Rgsc689/?
Genetic Background: involves: C57BL/6J * DBA/2J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000030830 Itgal / P24063 / Integrin alpha-L / P20701* / integrin subunit alpha L*  / complex / reaction






 

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