ENSMUSG00000032452


Mus musculus

Features
Gene ID: ENSMUSG00000032452
  
Biological name :Clstn2
  
Synonyms : Calsyntenin-2 / Clstn2 / Q9ER65
  
Possible biological names infered from orthology : Q9H4D0
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: E3.3
Gene start: 97444395
Gene end: 98033181
  
Corresponding Affymetrix probe sets: 10595871 (MoGene1.0st)   1422158_at (Mouse Genome 430 2.0 Array)   1441165_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000035027
Ensembl peptide - ENSMUSP00000124081
NCBI entrez gene - 64085     See in Manteia.
MGI - MGI:1929897
RefSeq - XM_006511334
RefSeq - NM_022319
RefSeq Peptide - NP_071714
swissprot - Q9ER65
Ensembl - ENSMUSG00000032452
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 clstn2ENSDARG00000060637Danio rerio
 si:ch211-276c2.2ENSDARG00000060638Danio rerio
 CLSTN2ENSGALG00000037387Gallus gallus
 CLSTN2ENSG00000158258Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Clstn1 / Q9EPL2 / Calsyntenin-1 Soluble Alc-alpha CTF1-alpha / O94985* / calsyntenin 1*ENSMUSG0000003995351
Clstn3 / Q99JH7 / Mus musculus calsyntenin 3 (Clstn3), transcript variant 2, mRNA. / Q9BQT9* / calsyntenin 3*ENSMUSG0000000815346


Protein motifs (from Interpro)
Interpro ID Name
 IPR002126  Cadherin
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR015919  Cadherin-like
 IPR026914  Calsyntenin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IEA
 biological_processGO:0050806 positive regulation of synaptic transmission IGI
 biological_processGO:0051965 positive regulation of synapse assembly IGI
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0014069 postsynaptic density IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0045211 postsynaptic membrane IDA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
Show

Allelic Composition: Fkrptvrm53/Fkrptvrm53
Genetic Background: C57BL/6J-Fkrptvrm53/Pjn

 MP:0008414 abnormal spatial reference memory "anomaly in the ability to recall spatial location information from previous encounters or training sessions in order to naviagate or perform other behavior using such locational cues" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fkrptvrm53/Fkrptvrm53
Genetic Background: C57BL/6J-Fkrptvrm53/Pjn

 MP:0012307 impaired spatial learning "impaired ability to ascertain or acquire spatial location information in order to improve navigation or other behavior using such location cues" [MGI:csmith]
Show

Allelic Composition: Fkrptvrm53/Fkrptvrm53
Genetic Background: C57BL/6J-Fkrptvrm53/Pjn

 MP:0020358 abnormal inhibitory synapse morphology "any structural anomaly in a synapse in which an action potential in the presynaptic cell reduces the probability of an action potential occurring in the postsynaptic cell" [GO:0060077]
Show

Allelic Composition: Fkrptvrm53/Fkrptvrm53
Genetic Background: C57BL/6J-Fkrptvrm53/Pjn

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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