ENSMUSG00000032702


Mus musculus
regulationKank1ankyrincellrepeat-containingdomainsignalingpathwayproteinrufflemembranebindingrepeatkankn-terminalmotifsuperfamilyneuronprojectiondevelopmentwntmigrationactinfilamentpolymerizationrhosignaltransductioninsulinreceptorwound

Features
Gene ID: ENSMUSG00000032702
  
Biological name :Kank1
  
Synonyms : Kank1 / KN motif and ankyrin repeat domains 1
  
Possible biological names infered from orthology : Q14678
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: B
Gene start: 25236975
Gene end: 25434496
  
Corresponding Affymetrix probe sets: 10462195 (MoGene1.0st)   1433742_at (Mouse Genome 430 2.0 Array)   1444711_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000116660
Ensembl peptide - ENSMUSP00000042177
NCBI entrez gene - 107351     See in Manteia.
MGI - MGI:2147707
RefSeq - XM_017318043
RefSeq - XM_006526589
RefSeq - XM_006526590
RefSeq - XM_011247113
RefSeq - NM_181404
RefSeq - XM_006526584
RefSeq - XM_006526585
RefSeq - XM_006526586
RefSeq - XM_006526587
RefSeq - XM_006526588
RefSeq Peptide - NP_852069
swissprot - E9Q944
swissprot - E9Q238
Ensembl - ENSMUSG00000032702
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kank1aENSDARG00000060102Danio rerio
 KANK1ENSGALG00000010158Gallus gallus
 KANK1ENSG00000107104Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kank2 / Q8BX02 / KN motif and ankyrin repeat domain-containing protein 2 / Q63ZY3* / KN motif and ankyrin repeat domains 2*ENSMUSG0000003219424
Kank4 / Q6P9J5 / KN motif and ankyrin repeat domain-containing protein 4 / Q5T7N3* / KN motif and ankyrin repeat domains 4*ENSMUSG0000003540723
Kank3 / Q9Z1P7 / Mus musculus KN motif and ankyrin repeat domains 3 (Kank3), transcript variant 2, mRNA. / Q6NY19* / KN motif and ankyrin repeat domains 3*ENSMUSG0000004209922


Protein motifs (from Interpro)
Interpro ID Name
 IPR002110  Ankyrin repeat
 IPR020683  Ankyrin repeat-containing domain
 IPR021939  Kank N-terminal motif
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
cellular component organizationanatomical structure developmentcellular developmental processcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentcellular component biogenesisregulation of biological qualityactin filament-based processresponse to endogenous stimulusresponse to chemicalresponse to stresscell adhesionestablishment or maintenance of cell polaritycellular component organizationanatomical structure developmentcellular developmental processcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentcellular component biogenesisregulation of biological qualityactin filament-based processresponse to endogenous stimulusresponse to chemicalresponse to stresscell adhesionestablishment or maintenance of cell polaritycellular component organizationanatomical structure developmentcellular developmental processcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentcellular component biogenesisregulation of biological qualityactin filament-based processresponse to endogenous stimulusresponse to chemicalresponse to stresscell adhesionestablishment or maintenance of cell polaritycellular component organizationanatomical structure developmentcellular developmental processcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentcellular component biogenesisregulation of biological qualityactin filament-based processresponse to endogenous stimulusresponse to chemicalresponse to stresscell adhesionestablishment or maintenance of cell polaritycellular component organizationanatomical structure developmentcellular developmental processcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentcellular component biogenesisregulation of biological qualityactin filament-based processresponse to endogenous stimulusresponse to chemicalresponse to stresscell adhesionestablishment or maintenance of cell polaritycellular component organizationanatomical structure developmentcellular developmental processcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentcellular component biogenesisregulation of biological qualityactin filament-based processresponse to endogenous stimulusresponse to chemicalresponse to stresscell adhesionestablishment or maintenance of cell polaritycellular component organizationanatomical structure developmentcellular developmental processcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentcellular component biogenesisregulation of biological qualityactin filament-based processresponse to endogenous stimulusresponse to chemicalresponse to stresscell adhesionestablishment or maintenance of cell polaritycellular component organizationanatomical structure developmentcellular developmental processcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentcellular component biogenesisregulation of biological qualityactin filament-based processresponse to endogenous stimulusresponse to chemicalresponse to stresscell adhesionestablishment or maintenance of cell polaritycellular component organizationanatomical structure developmentcellular developmental processcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentcellular component biogenesisregulation of biological qualityactin filament-based processresponse to endogenous stimulusresponse to chemicalresponse to stresscell adhesionestablishment or maintenance of cell polaritycellular component organizationanatomical structure developmentcellular developmental processcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentcellular component biogenesisregulation of biological qualityactin filament-based processresponse to endogenous stimulusresponse to chemicalresponse to stresscell adhesionestablishment or maintenance of cell polaritycellular cellular component organizationanatomicaanatomical structure developmentcellular cellular developmental processcell commcell communicationcellular cellular response to stimuluslocalizatlocalization of cellmovement movement of cell or subcellular componentcellular cellular component biogenesisregulatioregulation of biological qualityactin filactin filament-based processresponse response to endogenous stimulusresponse response to chemicalresponse response to stresscell adhecell adhesionestablishestablishment or maintenance of cell polarity
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
cellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellcellorganelleorganellemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0010977 negative regulation of neuron projection development ISO
 biological_processGO:0030177 positive regulation of Wnt signaling pathway ISO
 biological_processGO:0030336 negative regulation of cell migration ISO
 biological_processGO:0030837 negative regulation of actin filament polymerization ISO
 biological_processGO:0035024 negative regulation of Rho protein signal transduction ISO
 biological_processGO:0046627 negative regulation of insulin receptor signaling pathway ISO
 biological_processGO:0090303 positive regulation of wound healing ISO
 biological_processGO:1900025 negative regulation of substrate adhesion-dependent cell spreading ISO
 biological_processGO:1900028 negative regulation of ruffle assembly ISO
 biological_processGO:2000114 regulation of establishment of cell polarity ISO
 biological_processGO:2000393 negative regulation of lamellipodium morphogenesis ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0032587 ruffle membrane ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008013 beta-catenin binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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