ENSMUSG00000032743


Mus musculus

Features
Gene ID: ENSMUSG00000032743
  
Biological name :D430042O09Rik
  
Synonyms : D430042O09Rik / Mus musculus RIKEN cDNA D430042O09 (D430042O09Rik), transcript variant 2, mRNA. / Q8C753
  
Possible biological names infered from orthology : KIAA0556 / O60303
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: F3
Gene start: 125707888
Gene end: 125874793
  
Corresponding Affymetrix probe sets: 10557353 (MoGene1.0st)   10557355 (MoGene1.0st)   10557357 (MoGene1.0st)   10557359 (MoGene1.0st)   10557361 (MoGene1.0st)   10557372 (MoGene1.0st)   10557374 (MoGene1.0st)   10557394 (MoGene1.0st)   10557397 (MoGene1.0st)   1430042_at (Mouse Genome 430 2.0 Array)   1435366_at (Mouse Genome 430 2.0 Array)   1443334_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000065744
Ensembl peptide - ENSMUSP00000115955
Ensembl peptide - ENSMUSP00000118668
Ensembl peptide - ENSMUSP00000119527
NCBI entrez gene - 233865     See in Manteia.
MGI - MGI:2442760
RefSeq - XM_017322208
RefSeq - XM_006507716
RefSeq - XM_006507717
RefSeq - XM_006507718
RefSeq - XM_011241771
RefSeq - XM_011241774
RefSeq - XM_017322207
RefSeq - NM_001081022
RefSeq - NM_001358287
RefSeq Peptide - NP_001074491
RefSeq Peptide - NP_001345216
swissprot - F6XQI1
swissprot - F6UDS6
swissprot - Q8C753
swissprot - D3Z212
Ensembl - ENSMUSG00000032743
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-161j23.5ENSDARG00000094441Danio rerio
 si:dkey-161j23.6ENSDARG00000092347Danio rerio
 si:dkey-161j23.7ENSDARG00000092882Danio rerio
 KIAA0556ENSGALG00000043363Gallus gallus
 O60303ENSG00000047578Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008979  Galactose-binding-like domain superfamily
 IPR026704  Protein KIAA0556
 IPR027859  Domain of unknown function DUF4457


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000807 abnormal hippocampus morphology "absent or malformed deep lying structure of the cerebrum involved with memory storage and spatial navigation" [The Atlas of Mouse Development:ISBN 0-12-402035-6, MGI:Cls, J:38857]
Show

Allelic Composition: Foxp3sf/Y
Genetic Background: B6.Cg-Foxp3sf/J

 MP:0000917 obstructive hydrocephaly "hydrocephaly due to a block in cerebralspinal fluid flow in the ventricular system" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Foxp3sf/Y
Genetic Background: B6.Cg-Foxp3sf/J

 MP:0001891 hydroencephaly "excessive accumulation of cerebrospinal fluid in the brain, especially the cerebral ventricles, often leading to increased brain size and other brain trauma" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Foxp3sf/Y
Genetic Background: B6.Cg-Foxp3sf/J

 MP:0002958 aqueductal stenosis "the most common form of obstructive hydrocephaly and results from narrowing of the aqueduct of Sylvius, which connects the third and fourth ventricles" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Foxp3sf/Y
Genetic Background: B6.Cg-Foxp3sf/J

 MP:0008535 enlarged lateral ventricles "increased size of the cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube; they are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle" [MESH:A08.186.211.276.650, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Foxp3sf/Y
Genetic Background: B6.Cg-Foxp3sf/J

 MP:0013907 abnormal cerebrospinal fluid flow "any anomaly in the dynamic process by which CSF circulates from the sites of secretion to the sites of absorption according to a unidirectional rostrocaudal flow in ventricular cavities and a multidirectional flow in subarachnoid spaces; CSF produced by the choroid plexuses in the lateral ventricles travels through interventricular foramina to the third ventricle, and then the fourth ventricle via the cerebral aqueduct and finally to the subarachnoid spaces via the median aperture (foramen of Magendie) of the fourth ventricle; in the cranial subarachnoid space, CSF circulates rostrally to the villous sites of absorption or caudally to the spinal subarachnoid space; CSF circulation through the ventricular system is driven by motile cilia on ependymal cells of the brain; CSF flow is pulsatile, corresponding to the systolic pulse wave in choroidal arteries; additional factors such as respiratory waves, the subject s posture, jugular venous pressure and physical effort also modulate CSF flow dynamics and pressure" [MGI:Anna, PMID:22100360, PMID:24229449]
Show

Allelic Composition: Foxp3sf/Y
Genetic Background: B6.Cg-Foxp3sf/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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