ENSMUSG00000032750


Mus musculus

Features
Gene ID: ENSMUSG00000032750
  
Biological name :Gab3
  
Synonyms : Gab3 / GRB2-associated-binding protein 3 / Q8BSM5
  
Possible biological names infered from orthology : Q8WWW8
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: A7.3
Gene start: 74966843
Gene end: 75085458
  
Corresponding Affymetrix probe sets: 10605357 (MoGene1.0st)   1426589_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000041951
Ensembl peptide - ENSMUSP00000109739
Ensembl peptide - ENSMUSP00000109744
NCBI entrez gene - 100503280     See in Manteia.
NCBI entrez gene - 210710     See in Manteia.
MGI - MGI:2387324
RefSeq - NM_181584
RefSeq Peptide - NP_853615
swissprot - B1AYB9
swissprot - Q3V3J9
swissprot - Q8BSM5
Ensembl - ENSMUSG00000032750
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch73-92i20.1ENSDARG00000093081Danio rerio
 GAB3ENSGALG00000008408Gallus gallus
 GAB3ENSG00000160219Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gab2 / GAB4* / Q2WGN9* / Q9UQC2* / GRB2 associated binding protein 2* / GRB2 associated binding protein family member 4*ENSMUSG0000000450832
Gab1 / Q9QYY0 / GRB2-associated-binding protein 1 / Q13480*ENSMUSG0000003171428


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030225 macrophage differentiation IDA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: MafOfl/MafOfl
Genetic Background: either: 102/ElH or C3H/HeH

Allelic Composition: Gab3tm1Lrr/Gab3tm1Lrr
Genetic Background: involves: 129S4/SvJae * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr