ENSMUSG00000033107


Mus musculus

Features
Gene ID: ENSMUSG00000033107
  
Biological name :Rnf125
  
Synonyms : E3 ubiquitin-protein ligase RNF125 / Q9D9R0 / Rnf125
  
Possible biological names infered from orthology : Q96EQ8 / ring finger protein 125
  
Species: Mus musculus
  
Chr. number: 18
Strand: 1
Band: A2
Gene start: 20944625
Gene end: 20983848
  
Corresponding Affymetrix probe sets: 10454198 (MoGene1.0st)   1429399_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000058251
NCBI entrez gene - 67664     See in Manteia.
MGI - MGI:1914914
RefSeq - NM_026301
RefSeq - XM_006526188
RefSeq Peptide - NP_080577
swissprot - Q9D9R0
Ensembl - ENSMUSG00000033107
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q96EQ8ENSG00000101695Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q3U9F6 / Rnf166 / ring finger protein 166 / Q96A37*ENSMUSG0000001447031
Rnf138rt1 / ring finger protein 138, retrogene 1ENSMUSG0000008369530
Q9ET26 / Rnf114 / E3 ubiquitin-protein ligase RNF114 / Q9Y508* / ring finger protein 114*ENSMUSG0000000641829
Q9CQE0 / Rnf138 / E3 ubiquitin-protein ligase RNF138 / Q8WVD3* / ring finger protein 138*ENSMUSG0000002431727


Protein motifs (from Interpro)
Interpro ID Name
 IPR008598  Drought induced 19 protein type, zinc-binding domain
 IPR034734  Zinc finger C2HC RNF-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IEA
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0032480 negative regulation of type I interferon production IEA
 biological_processGO:0039536 negative regulation of RIG-I signaling pathway IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEP
 cellular_componentGO:0000139 Golgi membrane ISS
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0034098 VCP-NPL4-UFD1 AAA ATPase complex IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0002039 p53 binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity EXP
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031624 ubiquitin conjugating enzyme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0013154 increased KLRG1+ CD8 alpha beta T cell number "increase in the number of CD8+ alpha beta T cells that express KLRG1, a marker of effector and memory T cells" [MGI:csmith]
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Allelic Composition: Ptpn12tm1b(NCOM)Mfgc/Ptpn12tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Ptpn12tm1b(NCOM)Mfgc/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type






 

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