ENSMUSG00000033124


Mus musculus

Features
Gene ID: ENSMUSG00000033124
  
Biological name :Atg9a
  
Synonyms : Atg9a / autophagy-related protein 9A isoform b
  
Possible biological names infered from orthology : AC068946.2 / autophagy related 9A / Q7Z3C6
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: C4
Gene start: 75180860
Gene end: 75192196
  
Corresponding Affymetrix probe sets: 10355763 (MoGene1.0st)   1435784_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000139641
Ensembl peptide - ENSMUSP00000139731
Ensembl peptide - ENSMUSP00000140616
Ensembl peptide - ENSMUSP00000140012
Ensembl peptide - ENSMUSP00000139828
Ensembl peptide - ENSMUSP00000047449
Ensembl peptide - ENSMUSP00000139608
NCBI entrez gene - 245860     See in Manteia.
MGI - MGI:2138446
RefSeq - XM_011238687
RefSeq - XM_011238690
RefSeq - XM_011238689
RefSeq - XM_011238688
RefSeq - NM_001003917
RefSeq - NM_001288612
RefSeq - NM_001288613
RefSeq Peptide - NP_001003917
RefSeq Peptide - NP_001275541
RefSeq Peptide - NP_001275542
swissprot - Q3ZAQ4
swissprot - A0A087WRG3
swissprot - A0A087WP33
swissprot - A0A087WPL8
swissprot - A0A087WQ26
Ensembl - ENSMUSG00000033124
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atg9aENSDARG00000044551Danio rerio
 ATG9AENSGALG00000011649Gallus gallus
 AC068946.2ENSG00000284820Homo sapiens
 ATG9AENSG00000198925Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Atg9b / Q6EBV9 / Autophagy-related protein 9B / Q674R7* / autophagy related 9B*ENSMUSG0000003829542


Protein motifs (from Interpro)
Interpro ID Name
 IPR007241  Autophagy-related protein 9


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0031667 response to nutrient levels IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA


Pathways (from Reactome)
Pathway description
Macroautophagy


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002419 abnormal innate immunity "anomaly in the function of the early phase of the response to infection; normally, it is present at all times, does not increase with exposure to specific pathogens, and does not discriminate between pathogens" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Sncatm1Rosl/Sncatm1Rosl,Sncgtm1Vlb/Sncgtm1Vlb
Genetic Background: B6.129-Sncatm1Rosl Sncgtm1Vlb

 MP:0008260 abnormal autophagy "abnormal catabolic process involving the degradation of a cell s own components through the lysosomal machinery" [MGI:honda "Hiraoki Onda, Mouse Genome Informatics Curator"]
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Allelic Composition: Sncatm1Rosl/Sncatm1Rosl,Sncgtm1Vlb/Sncgtm1Vlb
Genetic Background: B6.129-Sncatm1Rosl Sncgtm1Vlb

 MP:0008564 increased interferon-beta secretion "increase in the production or release of one of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA with antiviral, antiproliferative, and immunomodulating activity" [MESH:D12.644.276.374.440.890.275]
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Allelic Composition: Sncatm1Rosl/Sncatm1Rosl,Sncgtm1Vlb/Sncgtm1Vlb
Genetic Background: B6.129-Sncatm1Rosl Sncgtm1Vlb

 MP:0008705 increased interleukin-6 secretion "increase in the production or release of a cytokine that stimulates the growth and differentiation of B-cells and is also a growth factor for hybridomas and plasmacytomas, and is produced by many different cells including T-cells, monocytes and fibroblasts" [MESH:D12.644.276.374.465.506]
Show

Allelic Composition: Sncatm1Rosl/Sncatm1Rosl,Sncgtm1Vlb/Sncgtm1Vlb
Genetic Background: B6.129-Sncatm1Rosl Sncgtm1Vlb

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: Sncatm1Rosl/Sncatm1Rosl,Sncgtm1Vlb/Sncgtm1Vlb
Genetic Background: B6.129-Sncatm1Rosl Sncgtm1Vlb

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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