ENSMUSG00000033450


Mus musculus

Features
Gene ID: ENSMUSG00000033450
  
Biological name :Tagap
  
Synonyms : B2RWW0 / Tagap / T-cell activation Rho GTPase-activating protein
  
Possible biological names infered from orthology : Q8N103 / T cell activation RhoGTPase activating protein
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: A1
Gene start: 7926000
Gene end: 7934897
  
Corresponding Affymetrix probe sets: 10441601 (MoGene1.0st)   10447629 (MoGene1.0st)   1460453_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000047431
NCBI entrez gene - 72536     See in Manteia.
MGI - MGI:3615484
RefSeq - NM_145968
RefSeq - XM_006523354
RefSeq Peptide - NP_666080
swissprot - B2RWW0
Ensembl - ENSMUSG00000033450
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TAGAPENSDARG00000043475Danio rerio
 tagapaENSDARG00000002353Danio rerio
 TAGAPENSGALG00000013747Gallus gallus
 TAGAPENSG00000164691Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tagap1 / P0CAX8 / T-cell activation GTPase-activating protein 1 / TAGAP* / Q8N103* / T cell activation RhoGTPase activating protein*ENSMUSG0000005203163
Q6IFT4 / Arhgap20 / Rho GTPase-activating protein 20 / Q9P2F6*ENSMUSG0000005319917
1700006A11Rik / RIKEN cDNA 1700006A11 geneENSMUSG0000002797315
Gm1527ENSMUSG0000007465514


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR008936  Rho GTPase activation protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0051607 defense response to virus IMP
 biological_processGO:0065009 regulation of molecular function IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001930 abnormal meiosis "malfunction in the process of nuclear division that results in gametes with one half the normal number of the original cell" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Fgf8tm2Moon/Fgf8tm1Mrc,Tg(Mef2c-cre)2Blk/0
Genetic Background: Not Specified

 MP:0002674 abnormal sperm motility "anomalies in the mobility of the spermatozoa" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Fgf8tm2Moon/Fgf8tm1Mrc,Tg(Mef2c-cre)2Blk/0
Genetic Background: Not Specified

 MP:0002675 asthenozoospermia "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Fgf8tm2Moon/Fgf8tm1Mrc,Tg(Mef2c-cre)2Blk/0
Genetic Background: Not Specified

 MP:0005169 abnormal male meiosis "malfunction in the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Fgf8tm2Moon/Fgf8tm1Mrc,Tg(Mef2c-cre)2Blk/0
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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