ENSMUSG00000033826


Mus musculus

Features
Gene ID: ENSMUSG00000033826
  
Biological name :Dnah8
  
Synonyms : Dnah8 / Dynein heavy chain 8, axonemal / Q91XQ0
  
Possible biological names infered from orthology : dynein axonemal heavy chain 8 / Q96JB1
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: A3.3
Gene start: 30624354
Gene end: 30875264
  
Corresponding Affymetrix probe sets: 10443598 (MoGene1.0st)   1424936_a_at (Mouse Genome 430 2.0 Array)   1425692_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000127878
NCBI entrez gene - 13417     See in Manteia.
MGI - MGI:107714
RefSeq - XM_006523592
RefSeq - NM_013811
RefSeq - XM_006523590
RefSeq - XM_006523591
RefSeq - XM_006523588
RefSeq Peptide - NP_038839
swissprot - Q91XQ0
Ensembl - ENSMUSG00000033826
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DNAH8ENSGALG00000010116Gallus gallus
 DNAH8ENSG00000124721Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dnah5 / Q8VHE6 / Dynein heavy chain 5, axonemal ENSMUSG0000002226260
Dnah10ENSMUSG0000003801129
Dnah17 / dynein axonemal heavy chain 17 / Q9UFH2*ENSMUSG0000003398728
Dnah2 / P0C6F1 / Dynein heavy chain 2, axonemal / Q9P225* / dynein axonemal heavy chain 2*ENSMUSG0000000523727
Dnah11 / dynein axonemal heavy chain 11 / Q96DT5*ENSMUSG0000001858127
Dnah1 / E9Q8T7 / Dynein heavy chain 1, axonemal / Q9P2D7* / dynein axonemal heavy chain 1*ENSMUSG0000001902726
Dnah3 / Q8BW94 / Dynein heavy chain 3, axonemal ENSMUSG0000005227325
Dnah6 / dynein axonemal heavy chain 6 / Q9C0G6*ENSMUSG0000005286125
Dnah7a / DNAH7* / Q8WXX0* / dynein axonemal heavy chain 7*ENSMUSG0000009614125
Dnah7c / DNAH7* / Q8WXX0* / dynein axonemal heavy chain 7*ENSMUSG0000010133725
Dnah12ENSMUSG0000002187924
Q9JHU4 / Dync1h1 / Cytoplasmic dynein 1 heavy chain 1 / Q14204* / dynein cytoplasmic 1 heavy chain 1*ENSMUSG0000001870722
Dnah14 / Q0VDD8* / dynein axonemal heavy chain 14*ENSMUSG0000004736921


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR004273  Dynein heavy chain domain
 IPR011704  ATPase, dynein-related, AAA domain
 IPR013594  Dynein heavy chain, domain-1
 IPR013602  Dynein heavy chain, domain-2
 IPR024317  Dynein heavy chain, AAA module D4
 IPR024743  Dynein heavy chain, coiled coil stalk
 IPR026983  Dynein heavy chain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR035699  Dynein heavy chain, hydrolytic ATP-binding dynein motor region D1
 IPR035706  Dynein heavy chain, ATP-binding dynein motor region D5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003341 cilium movement IBA
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0036158 outer dynein arm assembly IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0030286 dynein complex ISO
 cellular_componentGO:0031514 motile cilium IEA
 cellular_componentGO:0036157 outer dynein arm ISM
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0097228 sperm principal piece IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008569 ATP-dependent microtubule motor activity, minus-end-directed IBA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0045503 dynein light chain binding IBA
 molecular_functionGO:0045505 dynein intermediate chain binding IBA
 molecular_functionGO:0051959 dynein light intermediate chain binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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