ENSMUSG00000034203


Mus musculus
proteinChchd4cellularmitochondrialfoldingresponseintermembranespaceregulationmitochondrionoxidoreductaseactivitychchtransportpeptidyl-cysteineoxidationmaturationoxidativestressdnarepairimportexportnucleusdenovoposttranslationaloxidation-reductionprocessestablishmentlocalization

Features
Gene ID: ENSMUSG00000034203
  
Biological name :Chchd4
  
Synonyms : Chchd4 / Mitochondrial intermembrane space import and assembly protein 40 / Q8VEA4
  
Possible biological names infered from orthology : coiled-coil-helix-coiled-coil-helix domain containing 4 / Q8N4Q1
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: D1
Gene start: 91462172
Gene end: 91473546
  
Corresponding Affymetrix probe sets: 10546346 (MoGene1.0st)   1417233_at (Mouse Genome 430 2.0 Array)   1442431_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000041380
NCBI entrez gene - 72170     See in Manteia.
MGI - MGI:1919420
RefSeq - NM_133928
RefSeq Peptide - NP_598689
swissprot - Q8VEA4
Ensembl - ENSMUSG00000034203
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chchd4aENSDARG00000033376Danio rerio
 chchd4bENSDARG00000040707Danio rerio
 CHCHD4ENSGALG00000006328Gallus gallus
 CHCHD4ENSG00000163528Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AU015836 / expressed sequence AU015836 / CHCHD4* / Q8N4Q1* / coiled-coil-helix-coiled-coil-helix domain containing 4*ENSMUSG0000008104461


Protein motifs (from Interpro)
Interpro ID Name
 IPR010625  CHCH


Gene Ontology (GO)
macromolecule localizationestablishment of localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processoxidation-reduction processprotein foldingresponse to stressresponse to chemicalcellular response to stimuluscellular component organizationcellular localizationmacromolecule localizationestablishment of localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processoxidation-reduction processprotein foldingresponse to stressresponse to chemicalcellular response to stimuluscellular component organizationcellular localizationmacromolecule localizationestablishment of localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processoxidation-reduction processprotein foldingresponse to stressresponse to chemicalcellular response to stimuluscellular component organizationcellular localizationmacromolecule localizationestablishment of localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processoxidation-reduction processprotein foldingresponse to stressresponse to chemicalcellular response to stimuluscellular component organizationcellular localizationmacromolecule localizationestablishment of localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processoxidation-reduction processprotein foldingresponse to stressresponse to chemicalcellular response to stimuluscellular component organizationcellular localizationmacromolecule localizationestablishment of localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processoxidation-reduction processprotein foldingresponse to stressresponse to chemicalcellular response to stimuluscellular component organizationcellular localizationmacromolecule localizationestablishment of localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processoxidation-reduction processprotein foldingresponse to stressresponse to chemicalcellular response to stimuluscellular component organizationcellular localizationmacromolecule localizationestablishment of localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processoxidation-reduction processprotein foldingresponse to stressresponse to chemicalcellular response to stimuluscellular component organizationcellular localizationmacromolecule localizationestablishment of localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processoxidation-reduction processprotein foldingresponse to stressresponse to chemicalcellular response to stimuluscellular component organizationcellular localizationmacromolecule localizationestablishment of localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processoxidation-reduction processprotein foldingresponse to stressresponse to chemicalcellular response to stimuluscellular component organizationcellular localizationmacromolecmacromolecule localizationestablishmestablishment of localizationnitrogen cnitrogen compound metabolic processcellular mcellular metabolic processprimary meprimary metabolic processorganic suorganic substance metabolic processoxidation-oxidation-reduction processprotein foprotein foldingresponse tresponse to stressresponse tresponse to chemicalcellular rcellular response to stimuluscellular ccellular component organizationcellular lcellular localization
protein bindingoxidoreductase activityprotein bindingoxidoreductase activityprotein bindingoxidoreductase activityprotein bindingoxidoreductase activityprotein bindingoxidoreductase activityprotein bindingoxidoreductase activityprotein bindingoxidoreductase activityprotein bindingoxidoreductase activityprotein bindingoxidoreductase activityprotein bindingoxidoreductase activityprotein bindingprotein bindingoxidoreductase activityoxidoreductase activity
cellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0018171 peptidyl-cysteine oxidation ISS
 biological_processGO:0022417 protein maturation by protein folding ISS
 biological_processGO:0034599 cellular response to oxidative stress IDA
 biological_processGO:0043504 mitochondrial DNA repair IDA
 biological_processGO:0045041 protein import into mitochondrial intermembrane space ISO
 biological_processGO:0046825 regulation of protein export from nucleus IMP
 biological_processGO:0051084 "de novo" posttranslational protein folding ISO
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0072655 establishment of protein localization to mitochondrion IMP
 biological_processGO:1901857 positive regulation of cellular respiration IMP
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEP
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005758 mitochondrial intermembrane space ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015035 protein disulfide oxidoreductase activity ISO
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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