MP:0001326 | retinal degeneration | "pathological change in the thin layer of neural tissue lining the back of the eyeball, which contains visual receptors and can result in the impairment or cessation of retinal neural function" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(Loxl2)Acan/Gt(ROSA)26Sortm1.1(Loxl2)Acan Genetic Background: Not Specified
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MP:0003729 | abnormal photoreceptor outer segments | "malformation/anomalous structure of the photoreceptor layer which contains stacks of membranous discs that are rich in the visual pigment rhodopsin " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(Loxl2)Acan/Gt(ROSA)26Sortm1.1(Loxl2)Acan Genetic Background: Not Specified
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MP:0004021 | abnormal rod electrophysiology | "anomaly in the function of dark adapted vision mediated by the rods" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(Loxl2)Acan/Gt(ROSA)26Sortm1.1(Loxl2)Acan Genetic Background: Not Specified
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MP:0008144 | nyctalopia | "decreased ability to see clearly in reduced illumination; often due to a deficiency of vitamin A or to a retinal disorder" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", NCBI:matt "Matthew Mailman"] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(Loxl2)Acan/Gt(ROSA)26Sortm1.1(Loxl2)Acan Genetic Background: Not Specified
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MP:0008449 | abnormal retinal cone cell outer segment morphology | "any structural anomaly of the retinal cone cell region in which the visual pigment rhodopsin is in invaginations of the cell membrane" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(Loxl2)Acan/Gt(ROSA)26Sortm1.1(Loxl2)Acan Genetic Background: Not Specified
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MP:0008451 | retinal rod cell degeneration | "a retrogressive impairment of function or destruction of one of the photoreceptor cell types of the vertebrate retina, in which the photopigment is in stacks of membranous disks separate from the outer cell membrane" [MESH:A08.663.650.650.670.650] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(Loxl2)Acan/Gt(ROSA)26Sortm1.1(Loxl2)Acan Genetic Background: Not Specified
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MP:0008515 | thin retinal outer nuclear layer | "reduced thickness of the retinal layer that contains the nuclei and cell bodies of rods and cones" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(Loxl2)Acan/Gt(ROSA)26Sortm1.1(Loxl2)Acan Genetic Background: Not Specified
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MP:0012034 | abnormal a wave shape | "any anomaly in the graphical representation of the a wave in the electroretinogram; the a wave represents the general physiological health of the photoreceptors in the outer retina" [http://webvision.med.utah.edu, MGI:csmith] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(Loxl2)Acan/Gt(ROSA)26Sortm1.1(Loxl2)Acan Genetic Background: Not Specified
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