ENSMUSG00000034751


Mus musculus

Features
Gene ID: ENSMUSG00000034751
  
Biological name :Mast4
  
Synonyms : Mast4 / Microtubule-associated serine/threonine-protein kinase 4 / Q811L6
  
Possible biological names infered from orthology : microtubule associated serine/threonine kinase family member 4 / O15021
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: D1
Gene start: 102732486
Gene end: 103334497
  
Corresponding Affymetrix probe sets: 10411804 (MoGene1.0st)   1433394_at (Mouse Genome 430 2.0 Array)   1437404_at (Mouse Genome 430 2.0 Array)   1439318_at (Mouse Genome 430 2.0 Array)   1442158_at (Mouse Genome 430 2.0 Array)   1442382_at (Mouse Genome 430 2.0 Array)   1445866_at (Mouse Genome 430 2.0 Array)   1454591_at (Mouse Genome 430 2.0 Array)   1459387_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000128129
Ensembl peptide - ENSMUSP00000126625
Ensembl peptide - ENSMUSP00000128464
Ensembl peptide - ENSMUSP00000141977
Ensembl peptide - ENSMUSP00000132263
Ensembl peptide - ENSMUSP00000131910
Ensembl peptide - ENSMUSP00000131651
Ensembl peptide - ENSMUSP00000096808
Ensembl peptide - ENSMUSP00000126516
NCBI entrez gene - 328329     See in Manteia.
MGI - MGI:1918885
RefSeq - XM_017315532
RefSeq - XM_006517706
RefSeq - XM_006517707
RefSeq - XM_011244672
RefSeq - XM_011244673
RefSeq - XM_011244674
RefSeq - XM_017315527
RefSeq - XM_017315528
RefSeq - XM_017315529
RefSeq - XM_017315530
RefSeq - XM_017315531
RefSeq - NM_175171
RefSeq - XM_006517701
RefSeq - XM_006517702
RefSeq - XM_006517703
RefSeq - XM_006517704
RefSeq - XM_006517705
RefSeq Peptide - NP_780380
swissprot - E9Q6G0
swissprot - E9Q4Q9
swissprot - E9Q1M8
swissprot - F7AIF3
swissprot - E9PWX8
swissprot - A0A0A6YXG1
swissprot - Q811L6
swissprot - E9QPR4
swissprot - Q8BGU6
Ensembl - ENSMUSG00000034751
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MAST4ENSGALG00000014784Gallus gallus
 MAST4ENSG00000069020Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mast2 / microtubule associated serine/threonine kinase 2 / Q6P0Q8*ENSMUSG0000000381039
Mast1 / Q9R1L5 / Microtubule-associated serine/threonine-protein kinase 1 / Q9Y2H9* / microtubule associated serine/threonine kinase 1*ENSMUSG0000005369334
Mast3 / Q3U214 / Microtubule-associated serine/threonine-protein kinase 3 / O60307* / microtubule associated serine/threonine kinase 3*ENSMUSG0000003183331
Mastl / Q8C0P0 / microtubule associated serine/threonine kinase-like / Q96GX5*ENSMUSG000000267796


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR001478  PDZ domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR015022  Microtubule-associated serine/threonine-protein kinase, domain
 IPR023142  Microtubule-associated serine/threonine-protein kinase, pre-PK domain superfamily
 IPR028779  Microtubule-associated serine/threonine-protein kinase 2
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0045075 regulation of interleukin-12 biosynthetic process IEA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000120 malocclusion "perturbations in the normal patterned arrangement of the teeth or alignment of the jaw, resulting in the incorrect position of biting or chewing surfaces of the upper and lower teeth" [J:61509]
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Allelic Composition: Rag1m1Anu/Rag1m1Anu
Genetic Background: C57BL/6NCrlAnu-Rag1m1Anu

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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