ENSMUSG00000034845


Mus musculus

Features
Gene ID: ENSMUSG00000034845
  
Biological name :Plvap
  
Synonyms : plasmalemma vesicle associated protein / Plvap
  
Possible biological names infered from orthology : Q9BX97
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: B3.3
Gene start: 71497765
Gene end: 71511752
  
Corresponding Affymetrix probe sets: 10579525 (MoGene1.0st)   1418090_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000035404
NCBI entrez gene - 84094     See in Manteia.
MGI - MGI:1890497
RefSeq - NM_032398
RefSeq - XM_011242342
RefSeq Peptide - NP_115774
swissprot - G3X924
Ensembl - ENSMUSG00000034845
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000045684Gallus gallus
 PLVAPENSG00000130300Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009538  Plasmalemma vesicle-associated protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0002693 positive regulation of cellular extravasation IEA
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005901 caveola IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000186 decreased circulating HDL cholesterol level "lower than average level of high density lipoprotein in blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ptgdrtm1Dgen/Ptgdrtm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Plvaptm1.1Rvst/Plvaptm1.1Rvst,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129S4/SvJae * C3H * C57BL/6

Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0000195 hypocalcemia "subnormal concentrations of calcium ions in the circulating blood " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0000280 thin ventricular wall "decreased depth of the cardiac wall of the heart ventricles" [J:45302]
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Allelic Composition: Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Plvaptm1e(EUCOMM)Hmgu

 MP:0000585 kinked tail "a sharp bend or zig-zag in the tail" [J:61295]
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Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

Allelic Composition: Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu,Tg(TIE2GFP)287Sato/0
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0000692 small spleen "decreased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu,Tg(TIE2GFP)287Sato/0
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Plvaptm1e(EUCOMM)Hmgu

 MP:0001270 distended abdomen "abdomen appears curved outward or swollen; can be due to skeletal axial defects, enlarged visceral organs or megacolon" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ptgdrtm1Dgen/Ptgdrtm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Plvaptm1.1Rvst/Plvaptm1.1Rvst,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129S4/SvJae * C3H * C57BL/6

Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0001547 abnormal lipid level "anomalous concentrations of fat-soluble substances (molecules composed of carbon and hydrogen and are characteristically insoluble in water) in the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0001552 increased circulating triglyceride level "higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416]
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ptgdrtm1Dgen/Ptgdrtm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Plvaptm1.1Rvst/Plvaptm1.1Rvst,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129S4/SvJae * C3H * C57BL/6

Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0001577 anemia "less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
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Allelic Composition: Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Plvaptm1e(EUCOMM)Hmgu

Allelic Composition: Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu,Tg(TIE2GFP)287Sato/0
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ptgdrtm1Dgen/Ptgdrtm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Plvaptm1.1Rvst/Plvaptm1.1Rvst,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129S4/SvJae * C3H * C57BL/6

Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0001783 decreased white fat amount "reduced quantity of fat-storing cells/tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ptgdrtm1Dgen/Ptgdrtm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Plvaptm1.1Rvst/Plvaptm1.1Rvst,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129S4/SvJae * C3H * C57BL/6

 MP:0001785 edema "an accumulation of an excessive amount of watery fluid in cells or intercellular tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54065]
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Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

Allelic Composition: Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Plvaptm1e(EUCOMM)Hmgu

Allelic Composition: Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu,Tg(TIE2GFP)287Sato/0
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0001786 skin edema "accumulation of an excessive amount of fluid in the skin" [J:65039]
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Allelic Composition: Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Plvaptm1e(EUCOMM)Hmgu

 MP:0001914 hemorrhage "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Plvaptm1e(EUCOMM)Hmgu

 MP:0001944 abnormal pancreas morphology "malformation of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [il:Ira Lu , Mouse Genome Informatics Curator]
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Allelic Composition: Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu,Tg(TIE2GFP)287Sato/0
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Plvaptm1e(EUCOMM)Hmgu

 MP:0002447 abnormal erythrocyte morphology "structural anomaly of the cells in the blood that carry oxygen, red blood cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Plvaptm1e(EUCOMM)Hmgu

 MP:0002989 small kidney "reduced physical bulk one or both of the organs responsible for urine secretion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu,Tg(TIE2GFP)287Sato/0
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0003070 increased vascular permeability "greater or faster ability of the blood vessels to permit the passage of substances such as fluid, heat, or gases" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ptgdrtm1Dgen/Ptgdrtm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Plvaptm1.1Rvst/Plvaptm1.1Rvst,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129S4/SvJae * C3H * C57BL/6

Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0003180 abnormal pulmonary endothelial cell surface 
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Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0003288 intestinal edema "an accumulation of an excessive amount of serous fluid in the intestine or intestinal cells " [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0003658 abnormal capillaries "malformation in the minute blood vessels that connect arterioles and venules" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:96775]
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ptgdrtm1Dgen/Ptgdrtm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Plvaptm1.1Rvst/Plvaptm1.1Rvst,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129S4/SvJae * C3H * C57BL/6

Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

Allelic Composition: Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Plvaptm1e(EUCOMM)Hmgu

Allelic Composition: Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu,Tg(TIE2GFP)287Sato/0
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0003692 xanthoma "a deposit of cholesterol rich material in a tissue, most often in the skin but also seen in tendons and in the brain" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0003717 pallor "an unnatural paleness to the skin, generally attributable to anemia" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Plvaptm1e(EUCOMM)Hmgu

 MP:0003949 abnormal circulating lipid level "anomalous concentrations of fat-soluble substances (molecules composed of carbon and hydrogen and are characteristically insoluble in water) in the blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ptgdrtm1Dgen/Ptgdrtm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Plvaptm1.1Rvst/Plvaptm1.1Rvst,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129S4/SvJae * C3H * C57BL/6

 MP:0004247 small pancreas "decrease of the size of the pancreas compared to controls" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ptgdrtm1Dgen/Ptgdrtm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Plvaptm1.1Rvst/Plvaptm1.1Rvst,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129S4/SvJae * C3H * C57BL/6

Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

Allelic Composition: Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu,Tg(TIE2GFP)287Sato/0
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0004969 pale kidney "kidney lacks normal reddish coloration; often occurs with a bloodless or reduced vasculature condition" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu,Tg(TIE2GFP)287Sato/0
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0005178 increased total circulating cholesterol level "greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ptgdrtm1Dgen/Ptgdrtm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Plvaptm1.1Rvst/Plvaptm1.1Rvst,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129S4/SvJae * C3H * C57BL/6

Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0005324 ascites "accumulation or retention of fluid within the peritoneal cavity" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ptgdrtm1Dgen/Ptgdrtm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Plvaptm1.1Rvst/Plvaptm1.1Rvst,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129S4/SvJae * C3H * C57BL/6

Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0005416 abnormal circulating protein level "anomalous blood concentration of any of the macromolecules consisting of long chains of amino acids in peptide linkage" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0005419 hypoalbuminemia "blood albumin concentration below the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0005567 decreased circulating total protein level "less than the average total concentration of these macromolecules in the blood " [RGD:Rat Genome Database submission]
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ptgdrtm1Dgen/Ptgdrtm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Plvaptm1.1Rvst/Plvaptm1.1Rvst,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129S4/SvJae * C3H * C57BL/6

Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0006055 abnormal vascular endothelial cell morphology "malformation in the cells that line the vasculature" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0008853 decreased abdominal adipose tissue amount "reduction in amount of adipose tissue associated with internal organs" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0009283 decreased gonadal fat pad weight "less than average weight of the encapsulated adipose tissue associated with the ovaries or testes" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0009305 decreased retroperitoneal fat pad weight 
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Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0009395 persistence of primitive erythrocytes "presence of increased numbers of nucleated red blood cells at stages when these cells are normally replaced by mature, enucleated, red blood cells" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Plvaptm1e(EUCOMM)Hmgu

 MP:0009699 hyperchylomicronemia "increased plasma concentrations of chylomicrons, the large lipid droplet (up to 100 mm in diameter) of reprocessed lipid synthesized in epithelial cells of the small intestine and containing triacylglycerols, cholesterol esters, and several apolipoproteins" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0010155 abnormal intestine physiology "any functional anomaly of the digestive tube passing from the stomach to the anus" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0010402 ventricular septal defect "abnormal communications between the two lower chambers of the heart, including such defects in the perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular regions" [MESH:C14.240.400.560.540]
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Allelic Composition: Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Plvaptm1e(EUCOMM)Hmgu

 MP:0010831 partial lethality "the appearance of lower than Mendelian ratios of offspring of a given genotype due to death of some, but not all of the organisms" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ptgdrtm1Dgen/Ptgdrtm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Plvaptm1.1Rvst/Plvaptm1.1Rvst,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129S4/SvJae * C3H * C57BL/6

Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0011099 complete lethality throughout fetal growth and development "death of all organisms of a given genotype in a population between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
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Allelic Composition: Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Plvaptm1e(EUCOMM)Hmgu

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ptgdrtm1Dgen/Ptgdrtm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Plvaptm1.1Rvst/Plvaptm1.1Rvst,Tg(Tek-cre)12Flv/0
Genetic Background: B6.Cg-Plvaptm1.1Rvst Tg(Tek-cre)12Flv

Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: B6.Cg-Plvaptm1.2Rvst

 MP:0011310 abnormal kidney capillary morphology "any structural anomaly of the small branching blood vessels in the kidney that form a network between the arterioles and venules, where the exchange of water, oxygen, carbon dioxide, and other nutrient and waste chemical substances occurs between the blood and the surrounding tissues" [http://en.wikipedia.org/wiki/Capillary, MGI:csmith]
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Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

 MP:0011860 abnormal peritubular capillary endothelium morphology "any structural anomaly of the thin sheet of endothelial cells along the basal lamina of renal tubular cells characterized by their attenuated shape and numerous regularly-spaced transcellular pores (aka fenestrae or fenestrations); the fenestrae of peritubular capillaries differ from the fenestrae of glomerular capillaries in that they are much smaller and possess a small overlying diaphragm" [MGI:anna]
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Allelic Composition: Plvaptm1.2Rvst/Plvaptm1.2Rvst
Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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