ENSMUSG00000035150


Mus musculus

Features
Gene ID: ENSMUSG00000035150
  
Biological name :Eif2s3x
  
Synonyms : Eif2s3x / Eukaryotic translation initiation factor 2 subunit 3, X-linked / Q9Z0N1
  
Possible biological names infered from orthology : EIF2S3 / EIF2S3B / eukaryotic translation initiation factor 2 subunit gamma / eukaryotic translation initiation factor 2 subunit gamma B / P41091 / Q2VIR3
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: C3
Gene start: 94188707
Gene end: 94212862
  
Corresponding Affymetrix probe sets: 10605740 (MoGene1.0st)   1421895_at (Mouse Genome 430 2.0 Array)   1423744_x_at (Mouse Genome 430 2.0 Array)   1451090_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000109555
Ensembl peptide - ENSMUSP00000059395
NCBI entrez gene - 26905     See in Manteia.
MGI - MGI:1349431
RefSeq - NM_012010
RefSeq Peptide - NP_036140
swissprot - A2AAW9
swissprot - Q3TML6
swissprot - Q9Z0N1
Ensembl - ENSMUSG00000035150
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eif2s3ENSDARG00000008292Danio rerio
 EIF2S3ENSGALG00000016340Gallus gallus
 EIF2S3ENSG00000130741Homo sapiens
 Q2VIR3ENSG00000180574Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9Z0N2 / Eif2s3y / Eukaryotic translation initiation factor 2 subunit 3, Y-linked / EIF2S3* / P41091* / Q2VIR3* / EIF2S3B* / eukaryotic translation initiation factor 2 subunit gamma* / euk...ENSMUSG0000006904998


Protein motifs (from Interpro)
Interpro ID Name
 IPR000795  Transcription factor, GTP-binding domain
 IPR004161  Translation elongation factor EFTu-like, domain 2
 IPR009000  Translation protein, beta-barrel domain superfamily
 IPR009001  Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
 IPR015256  Translation initiation factor 2, gamma subunit, C-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005850 eukaryotic translation initiation factor 2 complex ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003743 translation initiation factor activity ISO
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0008135 translation factor activity, RNA binding ISS
 molecular_functionGO:0045296 cadherin binding ISO


Pathways (from Reactome)
Pathway description
ABC-family proteins mediated transport
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
Recycling of eIF2:GDP


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000038762 Abcf1 / Q6P542 / ATP-binding cassette, sub-family F (GCN20), member 1 / Q8NE71* / ATP binding cassette subfamily F member 1*  / complex / reaction
 ENSMUSG00000021116 Eif2s1 / Q6ZWX6 / Eukaryotic translation initiation factor 2 subunit 1 / P05198* / eukaryotic translation initiation factor 2 subunit alpha*  / complex
 ENSMUSG00000074656 Eif2s2 / Q99L45 / Eukaryotic translation initiation factor 2 subunit 2 / P20042* / eukaryotic translation initiation factor 2 subunit beta*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr