ENSMUSG00000035151


Mus musculus

Features
Gene ID: ENSMUSG00000035151
  
Biological name :Elmod2
  
Synonyms : Elmod2 / ELMO domain-containing protein 2 / Q8BGF6
  
Possible biological names infered from orthology : ELMO domain containing 2 / Q8IZ81
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: C2
Gene start: 83312632
Gene end: 83332486
  
Corresponding Affymetrix probe sets: 10579976 (MoGene1.0st)   1433730_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000052287
Ensembl peptide - ENSMUSP00000137044
Ensembl peptide - ENSMUSP00000147732
NCBI entrez gene - 244548     See in Manteia.
MGI - MGI:2445165
RefSeq - XM_006530980
RefSeq - NM_001170691
RefSeq - NM_178736
RefSeq - XM_006530979
RefSeq Peptide - NP_848851
RefSeq Peptide - NP_001164162
swissprot - Q8BGF6
swissprot - A0A1B0GRZ8
Ensembl - ENSMUSG00000035151
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 elmod2ENSDARG00000101669Danio rerio
 ELMOD2ENSGALG00000009836Gallus gallus
 ELMOD2ENSG00000179387Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Elmod1 / Q3V1U8 / ELMO domain-containing protein 1 / Q8N336* / ELMO domain containing 1*ENSMUSG0000004198652


Protein motifs (from Interpro)
Interpro ID Name
 IPR006816  ELMO domain
 IPR030724  ELMO domain-containing protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0050688 regulation of defense response to virus IEA
 molecular_functionGO:0005096 GTPase activator activity ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000562 polydactyly "greater than 5 digits on one or more autopods" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Egr1tm1b(NCOM)Mfgc/Egr1tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Egr1tm1b(NCOM)Mfgc/Tcp

 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Egr1tm1b(NCOM)Mfgc/Egr1tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Egr1tm1b(NCOM)Mfgc/Tcp

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
Show

Allelic Composition: Egr1tm1b(NCOM)Mfgc/Egr1tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Egr1tm1b(NCOM)Mfgc/Tcp

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
Show

Allelic Composition: Egr1tm1b(NCOM)Mfgc/Egr1tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Egr1tm1b(NCOM)Mfgc/Tcp

 MP:0001556 increased circulating HDL cholesterol level "higher than average level of high density lipoprotein in the blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:47439]
Show

Allelic Composition: Egr1tm1b(NCOM)Mfgc/Egr1tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Egr1tm1b(NCOM)Mfgc/Tcp

 MP:0005178 increased total circulating cholesterol level "greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Egr1tm1b(NCOM)Mfgc/Egr1tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Egr1tm1b(NCOM)Mfgc/Tcp

 MP:0005293 impaired glucose tolerance "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Egr1tm1b(NCOM)Mfgc/Egr1tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Egr1tm1b(NCOM)Mfgc/Tcp

 MP:0010024 increased total body fat amount "greater than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Egr1tm1b(NCOM)Mfgc/Egr1tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Egr1tm1b(NCOM)Mfgc/Tcp

 MP:0010124 decreased bone mineral content "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Egr1tm1b(NCOM)Mfgc/Egr1tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Egr1tm1b(NCOM)Mfgc/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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