ENSMUSG00000035699


Mus musculus

Features
Gene ID: ENSMUSG00000035699
  
Biological name :Slc51a
  
Synonyms : Q8R000 / Slc51a / solute carrier family 51, alpha subunit
  
Possible biological names infered from orthology : Q86UW1
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: B3
Gene start: 32475522
Gene end: 32487879
  
Corresponding Affymetrix probe sets: 10439068 (MoGene1.0st)   1451481_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000046286
NCBI entrez gene - 106407     See in Manteia.
MGI - MGI:2146634
RefSeq - NM_145932
RefSeq Peptide - NP_666044
swissprot - Q8R000
Ensembl - ENSMUSG00000035699
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc51aENSDARG00000045306Danio rerio
 SLC51AENSGALG00000007478Gallus gallus
 Q86UW1ENSG00000163959Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005178  Organic solute transporter subunit alpha/Transmembrane protein 184


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015721 bile acid and bile salt transport IPI
 biological_processGO:0032782 bile acid secretion IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071702 organic substance transport IPI
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015125 bile acid transmembrane transporter activity IPI
 molecular_functionGO:0022857 transmembrane transporter activity IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046982 protein heterodimerization activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000496 abnormal small intestine morphology "structural or developmental anomalies of the intestinum tenue " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Gfaptm4Ito/Gfaptm4Ito,Vimtm1Cba/Vimtm1Cba
Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas) or (involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Gad1tm1.1Rpa/Gad1+
Genetic Background: Not Specified

Allelic Composition: Slc51atm1Pda/Slc51atm1Pda
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0002644 decreased circulating triglyceride level "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Slc51atm1Pda/Slc51atm1Pda
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0003868 abnormal feces composition "increase or decrease in the amount of compunds normally found in the feces (fat, protein etc) or presence of material not normally seen in the feces" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Slc51atm1Pda/Slc51atm1Pda
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0003947 abnormal cholesterol level "anomaly in the concentration in the body of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Slc51atm1Pda/Slc51atm1Pda
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0004774 abnormal bile salt level "anomalous concentration of the steroid salts derived from cholesterol in the liver, produced as bile acids and secreted in the biliary sytem as bile salts; these play an important role in the digestion and absorption of fats" [MESH:D04.808.105, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Slc51atm1Pda/Slc51atm1Pda
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0005179 decreased total circulating cholesterol level "less than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Slc51atm1Pda/Slc51atm1Pda
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0005365 abnormal bile salt homeostasis "anomalous regulation of the steroid salts derived from cholesterol in the liver and which play an important role in the digestion and absorption of fats" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:86154]
Show

Allelic Composition: Slc51atm1Pda/Slc51atm1Pda
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

Allelic Composition: Abcc3tm1Kruh/Abcc3tm1Kruh,Slc51atm1Pda/Slc51atm1Pda
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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