ENSMUSG00000036131


Mus musculus

Features
Gene ID: ENSMUSG00000036131
  
Biological name :Frmd7
  
Synonyms : A2AD83 / FERM domain-containing protein 7 / Frmd7
  
Possible biological names infered from orthology : FERM domain containing 7 / Q6ZUT3
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: A5
Gene start: 50895180
Gene end: 50942710
  
Corresponding Affymetrix probe sets: 10604508 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000126628
Ensembl peptide - ENSMUSP00000057103
NCBI entrez gene - 385354     See in Manteia.
MGI - MGI:2686379
RefSeq - XM_011251013
RefSeq - XM_006541506
RefSeq - XM_006541507
RefSeq - XM_011251012
RefSeq - NM_001190332
RefSeq - XM_006541505
RefSeq Peptide - NP_001177261
swissprot - E9PXK8
swissprot - A2AD83
Ensembl - ENSMUSG00000036131
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 frmd7ENSDARG00000068958Danio rerio
 si:ch211-243g6.3ENSDARG00000070495Danio rerio
 FRMD7ENSGALG00000023843Gallus gallus
 FRMD7ENSG00000165694Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Farp1 / F8VPU2 / FERM, ARHGEF and pleckstrin domain-containing protein 1 / Q9Y4F1* / FERM, ARH/RhoGEF and pleckstrin domain protein 1*ENSMUSG0000002555538
Farp2 / Q91VS8 / FERM, ARHGEF and pleckstrin domain-containing protein 2 / O94887* / FERM, ARH/RhoGEF and pleckstrin domain protein 2*ENSMUSG0000003406636
Nf2 / P46662 / Merlin / P35240* / neurofibromin 2*ENSMUSG0000000907316
Msn / P26041 / Moesin / P26038*ENSMUSG0000003120716
Rdx / P26043 / radixin / P35241*ENSMUSG0000003205016
Ezr / Ezrin / P26040 / P15311*ENSMUSG0000005239715
Mylip / Q8BM54 / E3 ubiquitin-protein ligase MYLIP / Q8WY64* / myosin regulatory light chain interacting protein*ENSMUSG0000003817513


Protein motifs (from Interpro)
Interpro ID Name
 IPR000299  FERM domain
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR014847  FERM adjacent (FA)
 IPR018979  FERM, N-terminal
 IPR018980  FERM, C-terminal PH-like domain
 IPR019747  FERM conserved site
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR029071  Ubiquitin-like domain superfamily
 IPR035963  FERM superfamily, second domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0010592 positive regulation of lamellipodium assembly IDA
 biological_processGO:0010975 regulation of neuron projection development IMP
 biological_processGO:0032091 negative regulation of protein binding IDA
 biological_processGO:0051057 positive regulation of small GTPase mediated signal transduction IGI
 biological_processGO:0051497 negative regulation of stress fiber assembly IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection IDA
 cellular_componentGO:0043025 neuronal cell body IDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004647 decreased lumbar vertebrae number "reduced number of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MESH:National Library of Medicine_Medical Subject Headings]
Show

Allelic Composition: Foxo3tm1.1(KOMP)Vlcg/Foxo3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Foxo3tm1.1(KOMP)Vlcg/J

 MP:0010101 increased sacral vertebrae number "increase of any or all of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Foxo3tm1.1(KOMP)Vlcg/Foxo3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Foxo3tm1.1(KOMP)Vlcg/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr