ENSMUSG00000036533


Mus musculus

Features
Gene ID: ENSMUSG00000036533
  
Biological name :Cdc42ep3
  
Synonyms : Cdc42 effector protein 3 / Cdc42ep3 / Q9CQC5
  
Possible biological names infered from orthology : Q9UKI2
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: E3
Gene start: 79334025
Gene end: 79355091
  
Corresponding Affymetrix probe sets: 10453049 (MoGene1.0st)   1422642_at (Mouse Genome 430 2.0 Array)   1450700_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000067217
NCBI entrez gene - 260409     See in Manteia.
MGI - MGI:2384718
RefSeq - NM_026514
RefSeq - XM_006524295
RefSeq Peptide - NP_080790
swissprot - Q9CQC5
Ensembl - ENSMUSG00000036533
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdc42ep3ENSDARG00000052783Danio rerio
 CDC42EP3ENSGALG00000010551Gallus gallus
 Q9UKI2ENSG00000163171Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8JZX9 / Cdc42ep2 / Cdc42 effector protein 2 / O14613*ENSMUSG0000004566439


Protein motifs (from Interpro)
Interpro ID Name
 IPR000095  CRIB domain
 IPR029273  Cdc42 effector


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007266 Rho protein signal transduction IBA
 biological_processGO:0008360 regulation of cell shape IBA
 biological_processGO:0030838 positive regulation of actin filament polymerization IBA
 biological_processGO:0031274 positive regulation of pseudopodium assembly IBA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017049 GTP-Rho binding IBA


Pathways (from Reactome)
Pathway description
MAPK6/MAPK4 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000029454 O54992 / Mapkapk5 / MAP kinase-activated protein kinase 5 / Q8IW41* / mitogen-activated protein kinase-activated protein kinase 5*  / reaction
 ENSMUSG00000042688 Mapk6 / Q61532 / Mitogen-activated protein kinase 6 / Q16659*  / reaction
 ENSMUSG00000001833 Sept7 / septin-7 isoform 2 / Q16181* / septin 7*  / reaction






 

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