MP:0001175 | abnormal lung morphology | "malformed organ of respiration" [J:35802] |
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Allelic Composition: Rps6kb1tm1Gtho/Rps6kb1tm1Gtho,Tg(Ins2-Akt1*)3Mbb/0 Genetic Background: B6.Cg-Rps6kb1tm1Gtho Tg(Ins2-Akt1*)3Mbb
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MP:0002333 | abnormal lung compliance | "anomalous pulmonary volume change per unit pressure change " [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Rps6kb1tm1Gtho/Rps6kb1tm1Gtho,Tg(Ins2-Akt1*)3Mbb/0 Genetic Background: B6.Cg-Rps6kb1tm1Gtho Tg(Ins2-Akt1*)3Mbb
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MP:0004045 | abnormal cell cycle checkpoint function | "anomaly in the amount of time spent at the points in the cell cycle (end of G1 phase, end of G2 phase, and during metaphase) which prevent the cell from progressing to the next phase when conditions are unfavorable" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Tlx1tm1Sjk/Tlx1tm1Sjk,Tlx3tm1Sjk/Tlx3tm1Sjk Genetic Background: involves: 129S2/SvPas * 129X1/SvJ
Allelic Composition: Setd7tm1Frga/Setd7+ Genetic Background: involves: 129 * C57BL/6
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MP:0005166 | decreased susceptiblity to injury | "less than the normal reaction to trauma, especially that by physical means" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Rps6kb1tm1Gtho/Rps6kb1tm1Gtho,Tg(Ins2-Akt1*)3Mbb/0 Genetic Background: B6.Cg-Rps6kb1tm1Gtho Tg(Ins2-Akt1*)3Mbb
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MP:0008469 | abnormal protein level | "anomaly in the amount of any of the macromolecules consisting of long chains of amino acids in peptide linkage" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Rps6kb1tm1Gtho/Rps6kb1tm1Gtho,Tg(Ins2-Akt1*)3Mbb/0 Genetic Background: B6.Cg-Rps6kb1tm1Gtho Tg(Ins2-Akt1*)3Mbb
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MP:0008737 | abnormal spleen physiology | "any anomaly in the function of the organ that filters blood and stores red corpuscles and platelets" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tlx1tm1Sjk/Tlx1tm1Sjk,Tlx3tm1Sjk/Tlx3tm1Sjk Genetic Background: involves: 129S2/SvPas * 129X1/SvJ
Allelic Composition: Setd7tm1Frga/Setd7+ Genetic Background: involves: 129 * C57BL/6
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MP:0008874 | decreased sensitivity to xenobiotics | "increase in the dose or concentration of a foreign compound required to induce a specific level of response" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tlx1tm1Sjk/Tlx1tm1Sjk,Tlx3tm1Sjk/Tlx3tm1Sjk Genetic Background: involves: 129S2/SvPas * 129X1/SvJ
Allelic Composition: Setd7tm1Frga/Setd7+ Genetic Background: involves: 129 * C57BL/6
Allelic Composition: Setd7tm1.1Ital/Setd7tm1.1Ital Genetic Background: involves: C57BL/6 * CBA
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MP:0008944 | decreased sensitivity to induced cell death | "increase in the exposure level to an agent that is required to induce cessation of function at the cellular level" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tlx1tm1Sjk/Tlx1tm1Sjk,Tlx3tm1Sjk/Tlx3tm1Sjk Genetic Background: involves: 129S2/SvPas * 129X1/SvJ
Allelic Composition: Setd7tm1Frga/Setd7+ Genetic Background: involves: 129 * C57BL/6
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MP:0011101 | partial prenatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Tlx1tm1Sjk/Tlx1tm1Sjk,Tlx3tm1Sjk/Tlx3tm1Sjk Genetic Background: involves: 129S2/SvPas * 129X1/SvJ
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MP:0013258 | abnormal extracellular matrix morphology | "any structural anomaly of the structure lying external to one or more cells, which provides structural support for cells or tissues; in mammals, the extracellular matrix is completely external to the cell " [GO:0031012] |
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Allelic Composition: Setd7tm1.1Ital/Setd7tm1.1Ital Genetic Background: involves: C57BL/6 * CBA
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