ENSMUSG00000037519


Mus musculus

Features
Gene ID: ENSMUSG00000037519
  
Biological name :Ppfia1
  
Synonyms : Ppfia1 / protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
  
Possible biological names infered from orthology : PTPRF interacting protein alpha 1 / Q13136
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: F5
Gene start: 144476758
Gene end: 144553729
  
Corresponding Affymetrix probe sets: 10569583 (MoGene1.0st)   1435861_at (Mouse Genome 430 2.0 Array)   1455478_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000138312
Ensembl peptide - ENSMUSP00000126233
Ensembl peptide - ENSMUSP00000138175
Ensembl peptide - ENSMUSP00000138238
NCBI entrez gene - 233977     See in Manteia.
MGI - MGI:1924750
RefSeq - XM_017322224
RefSeq - XM_011241996
RefSeq - XM_011241997
RefSeq - XM_017322220
RefSeq - XM_017322221
RefSeq - XM_017322222
RefSeq - XM_017322223
RefSeq - NM_001033319
RefSeq - NM_001195086
RefSeq - XM_006508598
RefSeq - XM_006508599
RefSeq - XM_006508601
RefSeq - XM_006508603
RefSeq - XM_006508604
RefSeq - XM_006508605
RefSeq - XM_006508607
RefSeq - XM_006508608
RefSeq - XM_006508609
RefSeq - XM_006508610
RefSeq - XM_006508611
RefSeq - XM_006508612
RefSeq - XM_011241991
RefSeq - XM_011241992
RefSeq - XM_011241995
RefSeq Peptide - NP_001028491
RefSeq Peptide - NP_001182015
swissprot - B2RXW8
swissprot - S4R1I7
swissprot - B2RXQ2
swissprot - S4R1D4
Ensembl - ENSMUSG00000037519
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppfia1ENSDARG00000098674Danio rerio
 PPFIA1ENSGALG00000035774Gallus gallus
 PPFIA1ENSG00000131626Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ppfia2 / protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 / O75334* / PTPRF interacting protein alpha 2*ENSMUSG0000005382568
Ppfia4 / protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 / O75335* / PTPRF interacting protein alpha 4*ENSMUSG0000002645864
P60469 / Ppfia3 / protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 / O75145* / PTPRF interacting protein alpha 3*ENSMUSG0000000386361
Q8C8U0 / Ppfibp1 / PTPRF interacting protein, binding protein 1 (liprin beta 1) / Q86W92* / PPFIA binding protein 1*ENSMUSG0000001648717
O35711 / Ppfibp2 / PTPRF interacting protein, binding protein 2 (liprin beta 2) / Q8ND30* / PPFIA binding protein 2*ENSMUSG0000003652817
Kazn / Q69ZS8 / Kazrin / Q674X7* / kazrin, periplakin interacting protein*ENSMUSG000000406068


Protein motifs (from Interpro)
Interpro ID Name
 IPR001660  Sterile alpha motif domain
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR029515  LAR-interacting protein, Liprin
 IPR030438  Liprin-alpha-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0051497 negative regulation of stress fiber assembly ISO
 biological_processGO:1903077 negative regulation of protein localization to plasma membrane ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005925 focal adhesion ISO
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Serotonin Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Dopamine Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Receptor-type tyrosine-protein phosphatases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000028456 Q9Z1N9 / Unc13b / unc-13 homolog B (C. elegans) / O14795* / unc-13 homolog B*  / complex
 ENSMUSG00000034156 Q7TNF8 / Tspoap1 / Peripheral-type benzodiazepine receptor-associated protein 1 / O95153* / TSPO associated protein 1*  / complex
 ENSMUSG00000013236 Ptprs / B0V2N1 / Receptor-type tyrosine-protein phosphatase S / Q13332* / protein tyrosine phosphatase, receptor type S*  / complex / reaction
 ENSMUSG00000033295 Ptprf / A2A8L5 / Receptor-type tyrosine-protein phosphatase F / P10586* / protein tyrosine phosphatase, receptor type F*  / complex / reaction
 ENSMUSG00000028399 Ptprd / Q64487 / protein tyrosine phosphatase, receptor type, D / P23468*  / complex / reaction






 

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