ENSMUSG00000037824


Mus musculus
membraneTspan14tetraspaninplasmacellsurfacesignalingpathwayproteinintegralcomponentecdomainsuperfamilyperipherinconservedsitereceptorregulationnotchmaturationlocalizationtetraspanin-enrichedmicrodomainenzymebindingneutrophildegranulation

Features
Gene ID: ENSMUSG00000037824
  
Biological name :Tspan14
  
Synonyms : Q8QZY6 / Tetraspanin-14 / Tspan14
  
Possible biological names infered from orthology : Q8NG11
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: B
Gene start: 40906445
Gene end: 40966807
  
Corresponding Affymetrix probe sets: 10419073 (MoGene1.0st)   1423924_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000035263
Ensembl peptide - ENSMUSP00000153208
NCBI entrez gene - 52588     See in Manteia.
MGI - MGI:1196325
RefSeq - XM_017316081
RefSeq - NM_001316748
RefSeq - NM_145928
RefSeq - XM_006519261
RefSeq Peptide - NP_001303677
RefSeq Peptide - NP_666040
swissprot - Q8QZY6
Ensembl - ENSMUSG00000037824
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tspan14ENSDARG00000055938Danio rerio
 TSPAN14ENSGALG00000002414Gallus gallus
 Q8NG11ENSG00000108219Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P62080 / Tspan5 / tetraspanin 5 / P62079*ENSMUSG0000002815258
Tspan17 / tetraspanin 17 / Q96FV3*ENSMUSG0000002587557
Q8R3S2 / Tspan33 / Tetraspanin-33 / Q86UF1*ENSMUSG0000000176339
F7BWT7 / Tspan15 / Tetraspanin-15 / O95858*ENSMUSG0000003703132
Tspan10 / tetraspanin 10ENSMUSG0000003969129
Cd63 / P41731 / CD63 antigen / P08962* / CD63 molecule*ENSMUSG0000002535126
Cd151 / O35566 / CD151 antigen / P48509* / CD151 molecule (Raph blood group)*ENSMUSG0000002551024
Q62283 / Tspan7 / tetraspanin 7 / P41732* / AF241726.2*ENSMUSG0000005825424
Q9D1D1 / Tspan11 / Tetraspanin-11 / A1L157*ENSMUSG0000003035123
Tspan6 / tetraspanin 6 / O43657*ENSMUSG0000006737723
Q9QY33 / Tspan3 / tetraspanin 3 / O60637*ENSMUSG0000003232420


Protein motifs (from Interpro)
Interpro ID Name
 IPR000301  Tetraspanin
 IPR008952  Tetraspanin, EC2 domain superfamily
 IPR018499  Tetraspanin/Peripherin
 IPR018503  Tetraspanin, conserved site


Gene Ontology (GO)
cell communicationcellular response to stimulusnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationcellular localizationcell communicationcellular response to stimulusnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationcellular localizationcell communicationcellular response to stimulusnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationcellular localizationcell communicationcellular response to stimulusnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationcellular localizationcell communicationcellular response to stimulusnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationcellular localizationcell communicationcellular response to stimulusnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationcellular localizationcell communicationcellular response to stimulusnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationcellular localizationcell communicationcellular response to stimulusnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationcellular localizationcell communicationcellular response to stimulusnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationcellular localizationcell communicationcellular response to stimulusnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationcellular localizationcell communicationcell communicationcellular response tocellular response to stimulusnitrogen compound menitrogen compound metabolic processprimary metabolic prprimary metabolic processorganic substance meorganic substance metabolic processmacromolecule localimacromolecule localizationcellular localizatiocellular localization
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
cellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellcellmembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0007166 cell surface receptor signaling pathway IBA
 biological_processGO:0045747 positive regulation of Notch signaling pathway ISO
 biological_processGO:0051604 protein maturation IMP
 biological_processGO:0072659 protein localization to plasma membrane ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0097197 tetraspanin-enriched microdomain IDA
 molecular_functionGO:0019899 enzyme binding IPI


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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