ENSMUSG00000038292


Mus musculus

Features
Gene ID: ENSMUSG00000038292
  
Biological name :Ccdc155
  
Synonyms : Ccdc155 / Protein KASH5 / Q80VJ8
  
Possible biological names infered from orthology : coiled-coil domain containing 155 / Q8N6L0
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: B3
Gene start: 45183624
Gene end: 45204892
  
Corresponding Affymetrix probe sets: 10563149 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000113616
NCBI entrez gene - 384619     See in Manteia.
MGI - MGI:2687329
RefSeq - XM_017322329
RefSeq - NM_201374
RefSeq - XM_006540968
RefSeq - XM_011250871
RefSeq Peptide - NP_958762
swissprot - Q80VJ8
Ensembl - ENSMUSG00000038292
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q8N6L0ENSG00000161609Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR024950  Dual specificity phosphatase
 IPR028168  KASH5-like coiled-coil domain
 IPR028170  Protein KASH5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000724 double-strand break repair via homologous recombination IMP
 biological_processGO:0007015 actin filament organization IMP
 biological_processGO:0007129 synapsis IMP
 biological_processGO:0007283 spermatogenesis IMP
 biological_processGO:0034397 telomere localization IMP
 biological_processGO:0048477 oogenesis IMP
 biological_processGO:0051225 spindle assembly IDA
 biological_processGO:0051321 meiotic cell cycle IEA
 biological_processGO:0051653 spindle localization IDA
 biological_processGO:0090220 chromosome localization to nuclear envelope involved in homologous chromosome segregation IMP
 cellular_componentGO:0000781 chromosome, telomeric region IEA
 cellular_componentGO:0000800 lateral element IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005640 nuclear outer membrane IDA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0034993 meiotic nuclear membrane microtubule tethering complex IDA
 cellular_componentGO:0090619 meiotic spindle pole IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IDA
 molecular_functionGO:0070840 dynein complex binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001127 small ovary "reduced size of the female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
Show

Allelic Composition: Ccna2tm1Sot/Ccna2tm1Sot
Genetic Background: involves: 129P2/OlaHsd * BALB/c

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Ccna2tm1Sot/Ccna2tm1Sot
Genetic Background: involves: 129P2/OlaHsd * BALB/c

 MP:0001153 small seminiferous tubules "reduced diameter of the tubules in the testes where spermatogenesis occurs" [J:50844]
Show

Allelic Composition: Ccna2tm1Sot/Ccna2tm1Sot
Genetic Background: involves: 129P2/OlaHsd * BALB/c

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Ccna2tm1Sot/Ccna2tm1Sot
Genetic Background: involves: 129P2/OlaHsd * BALB/c

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Ccna2tm1Sot/Ccna2tm1Sot
Genetic Background: involves: 129P2/OlaHsd * BALB/c

 MP:0001931 abnormal oogenesis "atypical formation or failure to form the female germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
Show

Allelic Composition: Ccna2tm1Sot/Ccna2tm1Sot
Genetic Background: involves: 129P2/OlaHsd * BALB/c

 MP:0002216 abnormal seminiferous tubule morphology "malformation of the tubules in the testes where spermatogenesis occurs" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ccna2tm1Sot/Ccna2tm1Sot
Genetic Background: involves: 129P2/OlaHsd * BALB/c

 MP:0002777 absent ovarian follicles "lack of the sac-like structures in the ovaries that surround the ova" [J:42612, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ccna2tm1Sot/Ccna2tm1Sot
Genetic Background: involves: 129P2/OlaHsd * BALB/c

 MP:0004901 decreased male germ cell number "reduced numbers of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ccna2tm1Sot/Ccna2tm1Sot
Genetic Background: involves: 129P2/OlaHsd * BALB/c

 MP:0006379 abnormal spermatocyte morphology "anomaly in the number or structure of male germ cells that through meiosis give rise to spermatids " [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ccna2tm1Sot/Ccna2tm1Sot
Genetic Background: involves: 129P2/OlaHsd * BALB/c

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Ccna2tm1Sot/Ccna2tm1Sot
Genetic Background: involves: 129P2/OlaHsd * BALB/c

 MP:0009451 abnormal chromosome pairing during meiosis "an anomaly in the highly specific side-by-side association of homologous chromosomes during first prophase of meiosis" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ccna2tm1Sot/Ccna2tm1Sot
Genetic Background: involves: 129P2/OlaHsd * BALB/c

 MP:0010948 abnormal double-strand DNA break repair "any annomaly in the process of repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix" [GO:0006302]
Show

Allelic Composition: Ccna2tm1Sot/Ccna2tm1Sot
Genetic Background: involves: 129P2/OlaHsd * BALB/c

 MP:0013601 increased testis apoptosis "increase in the number of cells of the male reproductive glands undergoing programmed cell death" [MGI:Anna]
Show

Allelic Composition: Ccna2tm1Sot/Ccna2tm1Sot
Genetic Background: involves: 129P2/OlaHsd * BALB/c

 MP:0030024 abnormal meiotic attachment of telomere to nuclear envelope "any anomaly in the meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation" [GO:0070197]
Show

Allelic Composition: Ccna2tm1Sot/Ccna2tm1Sot
Genetic Background: involves: 129P2/OlaHsd * BALB/c

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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