ENSMUSG00000038300


Mus musculus

Features
Gene ID: ENSMUSG00000038300
  
Biological name :Pth2
  
Synonyms : parathyroid hormone 2 / Pth2 / Q91W27
  
Possible biological names infered from orthology : Q96A98
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B3
Gene start: 45180995
Gene end: 45181838
  
Corresponding Affymetrix probe sets: 10552871 (MoGene1.0st)   1450374_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000041047
Ensembl peptide - ENSMUSP00000147367
NCBI entrez gene - 114640     See in Manteia.
MGI - MGI:2152297
RefSeq - XM_017321931
RefSeq - NM_053256
RefSeq - XM_006540564
RefSeq - XM_006540565
RefSeq - XM_017321930
RefSeq - XM_006540562
RefSeq - XM_006540563
RefSeq Peptide - NP_444486
swissprot - Q91W27
swissprot - A0A1B0GR43
Ensembl - ENSMUSG00000038300
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pth2ENSDARG00000022951Danio rerio
 PTH2ENSG00000142538Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR029396  Tuberoinfundibular peptide of 39 residues


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006171 cAMP biosynthetic process TAS
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0005102 signaling receptor binding TAS


Pathways (from Reactome)
Pathway description
Class B/2 (Secretin family receptors)
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001119 abnormal female reproductive anatomy "anomalous structure of the organs associated with producing offspring in the gender that bears the offspring" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Enamtm1.1Jcch/Enam+
Genetic Background: C57BL/6-Enamtm1.1Jcch

 MP:0001127 small ovary "reduced size of the female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
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Allelic Composition: Enamtm1.1Jcch/Enam+
Genetic Background: C57BL/6-Enamtm1.1Jcch

 MP:0001145 abnormal male reproductive anatomy "anomalous structure of the organs associated with producing offspring in the gender that produces spermatozoa" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Enamtm1.1Jcch/Enam+
Genetic Background: C57BL/6-Enamtm1.1Jcch

 MP:0001146 abnormal testis morphology "anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Enamtm1.1Jcch/Enam+
Genetic Background: C57BL/6-Enamtm1.1Jcch

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Enamtm1.1Jcch/Enam+
Genetic Background: C57BL/6-Enamtm1.1Jcch

 MP:0001924 infertility "inability to produce live offspring" [J:47225]
Show

Allelic Composition: Enamtm1.1Jcch/Enam+
Genetic Background: C57BL/6-Enamtm1.1Jcch

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Enamtm1.1Jcch/Enam+
Genetic Background: C57BL/6-Enamtm1.1Jcch

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
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Allelic Composition: Enamtm1.1Jcch/Enam+
Genetic Background: C57BL/6-Enamtm1.1Jcch

Allelic Composition: Pth2tm1Vlcg/Pth2tm1Vlcg,Tg(CAG-LacZ,-Pth2)1Tbu/0,Tg(Prm-cre)58Og/0
Genetic Background: involves: 129 * C57BL/6

 MP:0001930 abnormal meiosis "malfunction in the process of nuclear division that results in gametes with one half the normal number of the original cell" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Enamtm1.1Jcch/Enam+
Genetic Background: C57BL/6-Enamtm1.1Jcch

 MP:0002160 abnormal reproductive system morphology "structural or developmental anomaly of any of the tissues involved in the reproductive system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Enamtm1.1Jcch/Enam+
Genetic Background: C57BL/6-Enamtm1.1Jcch

 MP:0002777 absent ovarian follicles "lack of the sac-like structures in the ovaries that surround the ova" [J:42612, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Enamtm1.1Jcch/Enam+
Genetic Background: C57BL/6-Enamtm1.1Jcch

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Enamtm1.1Jcch/Enam+
Genetic Background: C57BL/6-Enamtm1.1Jcch

 MP:0004910 decreased seminal gland weight "reduction in the weight of one or both of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Enamtm1.1Jcch/Enam+
Genetic Background: C57BL/6-Enamtm1.1Jcch

 MP:0006380 abnormal spermatid morphology "anomaly in the number or structure of the male germ cells that without further cell division give rise to mature spermatozoa" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Enamtm1.1Jcch/Enam+
Genetic Background: C57BL/6-Enamtm1.1Jcch

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000032492 Pth1r / P41593 / Parathyroid hormone/parathyroid hormone-related peptide receptor / Q03431* / parathyroid hormone 1 receptor*  / complex / reaction
 ENSMUSG00000025946 Pth2r / Q91V95 / Parathyroid hormone 2 receptor / P49190*  / complex / reaction






 

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