ENSMUSG00000038651


Mus musculus

Features
Gene ID: ENSMUSG00000038651
  
Biological name :Sycp2l
  
Synonyms : A0A0M3U1B0 / Sycp2l / Synaptonemal complex protein 2-like
  
Possible biological names infered from orthology : Q5T4T6
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: A3.3
Gene start: 41114307
Gene end: 41174351
  
Corresponding Affymetrix probe sets: 10404737 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000121296
Ensembl peptide - ENSMUSP00000115127
NCBI entrez gene - 637277     See in Manteia.
MGI - MGI:2685114
RefSeq - NM_001324525
RefSeq Peptide - NP_001311454
swissprot - A0A0M3U1B0
Ensembl - ENSMUSG00000038651
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q5T4T6ENSG00000153157Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Sycp2 / Q9CUU3 / Synaptonemal complex protein 2 / Q9BX26*ENSMUSG0000006044523


Protein motifs (from Interpro)
Interpro ID Name
 IPR024835  Synaptonemal complex protein 1/2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0060548 negative regulation of cell death IMP
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000780 condensed nuclear chromosome, centromeric region ISO
 cellular_componentGO:0000800 lateral element IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Sptbn1tm1c(EUCOMM)Wtsi/Sptbn1tm1c(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Sptbn1tm1c(EUCOMM)Wtsi/Sptbn1tm1c(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0005431 oocyte depletion "reduced numbers or absence of germ cells in the female" [llw2:Linda Washburn , Mouse Genome Informatics Curator, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Sptbn1tm1c(EUCOMM)Wtsi/Sptbn1tm1c(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0008995 early reproductive senescence "loss of reproductive capacity occurring at an earlier than expected age" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Sptbn1tm1c(EUCOMM)Wtsi/Sptbn1tm1c(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0011121 decreased primordial ovarian follicle number "fewer than normal numbers of the ovarian follicle in which the primary oocyte is surrounded by a single layer of flattened follicular cells; primordial follicles are indiscernible to the naked eye and develop to primary, secondary, and finally mature vesicular follicles" [MGI:csmith]
Show

Allelic Composition: Sptbn1tm1c(EUCOMM)Wtsi/Sptbn1tm1c(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0011125 decreased primary ovarian follicle number "fewer than normal numbers of the ovarian follicle prior to the appearance of an antrum, normally marked by developmental changes in the primary oocyte and follicular cells so that the latter form one or more layers of cuboidal or columnar cells; the follicle becomes surrounded by a sheath of stroma, the theca" [MGI:csmith]
Show

Allelic Composition: Sptbn1tm1c(EUCOMM)Wtsi/Sptbn1tm1c(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0011129 decreased secondary ovarian follicle number "fewer than normal numbers of the ovarian follicle in which the primary oocyte attains its full size and is surrounded by an extracellular glycoprotein layer (zona pellucida) that separates it from a peripheral layer of follicular cells permeated by one or more fluid-filled antra; the primary oocyte occupies the cumulus oophorus while the theca of the follicle develops into internal and external layers" [MGI:csmith]
Show

Allelic Composition: Sptbn1tm1c(EUCOMM)Wtsi/Sptbn1tm1c(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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