ENSMUSG00000039252


Mus musculus

Features
Gene ID: ENSMUSG00000039252
  
Biological name :Lgi2
  
Synonyms : Leucine-rich repeat LGI family member 2 / Lgi2 / Q8K4Z0
  
Possible biological names infered from orthology : Q8N0V4
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: C1
Gene start: 52533517
Gene end: 52566462
  
Corresponding Affymetrix probe sets: 10530029 (MoGene1.0st)   1440147_at (Mouse Genome 430 2.0 Array)   1457040_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000040436
Ensembl peptide - ENSMUSP00000143707
NCBI entrez gene - 246316     See in Manteia.
MGI - MGI:2180196
RefSeq - XM_006503965
RefSeq - NM_001310604
RefSeq - NM_144945
RefSeq Peptide - NP_659194
RefSeq Peptide - NP_001297533
swissprot - Q50DZ7
swissprot - Q8K4Z0
Ensembl - ENSMUSG00000039252
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lgi2aENSDARG00000111069Danio rerio
 lgi2bENSDARG00000069701Danio rerio
 LGI2ENSGALG00000043283Gallus gallus
 LGI2ENSG00000153012Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lgi1 / Q9JIA1 / Leucine-rich glioma-inactivated protein 1 / O95970* / leucine rich glioma inactivated 1*ENSMUSG0000006724252
Lgi3 / Q8K406 / Leucine-rich repeat LGI family member 3 / Q8N145*ENSMUSG0000003359547
Lgi4 / Q8K1S1 / Leucine-rich repeat LGI family member 4 / Q8N135*ENSMUSG0000003656037
Lrig3 / Q6P1C6 / Leucine-rich repeats and immunoglobulin-like domains protein 3 / Q6UXM1* / leucine rich repeats and immunoglobulin like domains 3*ENSMUSG0000002010518
Lrig1 / P70193 / Leucine-rich repeats and immunoglobulin-like domains protein 1 / Q96JA1* / leucine rich repeats and immunoglobulin like domains 1*ENSMUSG0000003002918
Lrig2 / Q52KR2 / leucine-rich repeats and immunoglobulin-like domains 2 / O94898*ENSMUSG0000003291318
Adgra3 / Q7TT36 / Adhesion G protein-coupled receptor A3 / Q8IWK6*ENSMUSG0000002909013
Adgra2 / Q91ZV8 / Adhesion G protein-coupled receptor A2 / Q96PE1*ENSMUSG0000003148613
Vasn / Q9CZT5 / vasorin / Q6EMK4*ENSMUSG0000003964612
Adgra1 / Q8C4G9 / Adhesion G protein-coupled receptor A1 / Q86SQ6*ENSMUSG000000254756


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR005492  Leucine-rich glioma-inactivated , EPTP repeat
 IPR009039  EAR
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
LGI-ADAM interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000040537 Adam22 / Q9R1V6 / Disintegrin and metalloproteinase domain-containing protein 22 / Q9P0K1* / ADAM metallopeptidase domain 22*  / complex / reaction
 ENSMUSG00000025964 Adam23 / Q9R1V7 / Disintegrin and metalloproteinase domain-containing protein 23 / O75077* / ADAM metallopeptidase domain 23*  / complex / reaction






 

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