ENSMUSG00000039660


Mus musculus

Features
Gene ID: ENSMUSG00000039660
  
Biological name :Spout1
  
Synonyms : Q3UHX9 / Spout1 / SPOUT domain containing methyltransferase 1
  
Possible biological names infered from orthology : Q5T280
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: B
Gene start: 30173453
Gene end: 30178459
  
Corresponding Affymetrix probe sets: 10481420 (MoGene1.0st)   1434119_at (Mouse Genome 430 2.0 Array)   1455004_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000097793
NCBI entrez gene - 227695     See in Manteia.
MGI - MGI:106544
RefSeq - NM_172660
RefSeq Peptide - NP_766248
swissprot - Q3UHX9
Ensembl - ENSMUSG00000039660
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spout1ENSDARG00000019707Danio rerio
 SPOUT1ENSGALG00000004622Gallus gallus
 Q5T280ENSG00000198917Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003750  Putative RNA methyltransferase
 IPR012340  Nucleic acid-binding, OB-fold
 IPR029026  tRNA (guanine-N1-)-methyltransferase, N-terminal
 IPR029028  Alpha/beta knot methyltransferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0010608 posttranscriptional regulation of gene expression IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0035196 production of miRNAs involved in gene silencing by miRNA IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051661 maintenance of centrosome location IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore ISO
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0031616 spindle pole centrosome IEA
 cellular_componentGO:0072686 mitotic spindle IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0035198 miRNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0006043 decreased apoptosis "less than normal cell death" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Spout1tm1Mxu/Spout1+,Dffatm1Mxu/Dffatm1Mxu
Genetic Background: involves: 129 * C57BL/6

 MP:0008280 male germ cell apoptosis "presence of male germs cells that undergo programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Abcg8tm1Elk/Abcg8+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0008944 decreased sensitivity to induced cell death "increase in the exposure level to an agent that is required to induce cessation of function at the cellular level" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Abcg8tm1Elk/Abcg8+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0011094 complete embryonic lethality before implantation "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]
Show

Allelic Composition: Abcg8tm1Elk/Abcg8+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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