ENSMUSG00000040132


Mus musculus

Features
Gene ID: ENSMUSG00000040132
  
Biological name :Svs2
  
Synonyms : seminal vesicle secretory protein 2 / Svs2
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: H3
Gene start: 164235929
Gene end: 164238466
  
Corresponding Affymetrix probe sets: 10489451 (MoGene1.0st)   1422427_a_at (Mouse Genome 430 2.0 Array)   1456188_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000042389
Ensembl peptide - ENSMUSP00000104999
NCBI entrez gene - 53878     See in Manteia.
MGI - MGI:1858275
RefSeq - NM_017390
RefSeq Peptide - NP_059086
swissprot - Q8BS30
Ensembl - ENSMUSG00000040132
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Svs3a / seminal vesicle secretory protein 3AENSMUSG0000001700328
Svs3b / seminal vesicle secretory protein 3BENSMUSG0000005038328


Protein motifs (from Interpro)
Interpro ID Name
 IPR002080  Seminal vesicle protein II, conserved site
 IPR018942  Seminal vesicle protein repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009566 fertilization IDA
 biological_processGO:0048240 sperm capacitation IDA
 cellular_componentGO:0001669 acrosomal vesicle IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
Show

Allelic Composition: Gjb6tm2.2Kwi/Gjb6tm2.2Kwi
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * CD-1 * SJL

Allelic Composition: Svs2tm2Kemi/Svs2tm2Kemi
Genetic Background: involves: 129 * C57BL/6N

 MP:0002674 abnormal sperm motility "anomalies in the mobility of the spermatozoa" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Gjb6tm2.2Kwi/Gjb6tm2.2Kwi
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * CD-1 * SJL

Allelic Composition: Svs2tm2Kemi/Svs2tm2Kemi,Tg(CAG-RFP,Acr-EGFP)RBGS002Osb/0
Genetic Background: involves: 129 * C57BL/6 * C57BL/6N * DBA/2

 MP:0003698 abnormal male reproductive system physiology "anomaly in the function of the male organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gjb6tm2.2Kwi/Gjb6tm2.2Kwi
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * CD-1 * SJL

Allelic Composition: Svs2tm2Kemi/Svs2tm2Kemi
Genetic Background: involves: 129 * C57BL/6N

 MP:0004543 abnormal sperm physiology "anomaly in the normal function of spermatozoa" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gjb6tm2.2Kwi/Gjb6tm2.2Kwi
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * CD-1 * SJL

Allelic Composition: Svs2tm1Kemi/Svs2tm1Kemi,Tg(CAG-RFP,Acr-EGFP)RBGS002Osb/0
Genetic Background: involves: 129 * C57BL/6 * C57BL/6N * DBA/2

Allelic Composition: Svs2tm2Kemi/Svs2tm2Kemi
Genetic Background: involves: 129 * C57BL/6N

Allelic Composition: Svs2tm2Kemi/Svs2tm2Kemi,Tg(CAG-RFP,Acr-EGFP)RBGS002Osb/0
Genetic Background: involves: 129 * C57BL/6 * C57BL/6N * DBA/2

 MP:0005292 improved glucose tolerance "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Sufutm1b(KOMP)Wtsi/Sufutm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Sufutm1b(KOMP)Wtsi/Ucd

 MP:0013288 premature acrosome reaction "spontaneous initiation of the cellular exocytosis that allows sperm to penetrate the zona pellucida of ovulated eggs, occurring prior to encountering conditions that induce sperm capacitation" [MGI:smb]
Show

Allelic Composition: Svs2tm1Kemi/Svs2tm1Kemi,Tg(CAG-RFP,Acr-EGFP)RBGS002Osb/0
Genetic Background: involves: 129 * C57BL/6 * C57BL/6N * DBA/2

Allelic Composition: Svs2tm2Kemi/Svs2tm2Kemi,Tg(CAG-RFP,Acr-EGFP)RBGS002Osb/0
Genetic Background: involves: 129 * C57BL/6 * C57BL/6N * DBA/2

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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