ENSMUSG00000040434


Mus musculus

Features
Gene ID: ENSMUSG00000040434
  
Biological name :Large2
  
Synonyms : Large2 / LARGE xylosyl- and glucuronyltransferase 2 Xylosyltransferase LARGE2 Beta-1,3-glucuronyltransferase LARGE2 / Q5XPT3
  
Possible biological names infered from orthology : LARGE xylosyl- and glucuronyltransferase 2 / Q8N3Y3
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: E1
Gene start: 92365046
Gene end: 92374869
  
Corresponding Affymetrix probe sets: 10485131 (MoGene1.0st)   1434007_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000135619
Ensembl peptide - ENSMUSP00000135400
Ensembl peptide - ENSMUSP00000135451
Ensembl peptide - ENSMUSP00000064128
Ensembl peptide - ENSMUSP00000088070
Ensembl peptide - ENSMUSP00000106915
Ensembl peptide - ENSMUSP00000135024
Ensembl peptide - ENSMUSP00000135118
NCBI entrez gene - 228366     See in Manteia.
MGI - MGI:2443769
RefSeq - XM_011239462
RefSeq - NM_001166633
RefSeq - NM_001290773
RefSeq - NM_001290774
RefSeq - NM_001290775
RefSeq - NM_172670
RefSeq - XM_006499254
RefSeq - XM_006499256
RefSeq - XM_011239458
RefSeq - XM_011239459
RefSeq - XM_011239461
RefSeq Peptide - NP_766258
RefSeq Peptide - NP_001277704
RefSeq Peptide - NP_001160105
RefSeq Peptide - NP_001277702
RefSeq Peptide - NP_001277703
swissprot - Q5XPT3
swissprot - H3BKM6
swissprot - Q14AT0
swissprot - H3BL20
swissprot - A2AHG6
Ensembl - ENSMUSG00000040434
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LARGE2ENSGALG00000008418Gallus gallus
 LARGE2ENSG00000165905Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Large1 / Q9Z1M7 / LARGE xylosyl- and glucuronyltransferase 1 Xylosyltransferase LARGE Beta-1,3-glucuronyltransferase LARGE / O95461* / LARGE xylosyl- and glucuronyltransferase 1*ENSMUSG0000000438362
B4gat1 / Q8BWP8 / Beta-1,4-glucuronyltransferase 1 / O43505*ENSMUSG0000004737914
Q3U4G3 / Xxylt1 / xyloside xylosyltransferase 1 / Q8NBI6*ENSMUSG0000004743410


Protein motifs (from Interpro)
Interpro ID Name
 IPR002495  Glycosyl transferase, family 8
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0035269 protein O-linked mannosylation ISS
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0002162 dystroglycan binding IDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0015020 glucuronosyltransferase activity IDA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IMP
 molecular_functionGO:0042285 xylosyltransferase activity IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
O-linked glycosylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Hfe2tm1Nca/Hfe2tm1Nca
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000047379 B4gat1 / Q8BWP8 / Beta-1,4-glucuronyltransferase 1 / O43505*  / complex






 

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