ENSMUSG00000040618


Mus musculus

Features
Gene ID: ENSMUSG00000040618
  
Biological name :Pck2
  
Synonyms : Pck2 / Phosphoenolpyruvate carboxykinase [GTP], mitochondrial / Q8BH04
  
Possible biological names infered from orthology : phosphoenolpyruvate carboxykinase 2, mitochondrial / Q16822
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: C3
Gene start: 55540266
Gene end: 55551242
  
Corresponding Affymetrix probe sets: 10415248 (MoGene1.0st)   1425615_a_at (Mouse Genome 430 2.0 Array)   1452620_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000154736
Ensembl peptide - ENSMUSP00000154762
Ensembl peptide - ENSMUSP00000038555
Ensembl peptide - ENSMUSP00000153733
Ensembl peptide - ENSMUSP00000154015
Ensembl peptide - ENSMUSP00000154072
Ensembl peptide - ENSMUSP00000154245
NCBI entrez gene - 74551     See in Manteia.
MGI - MGI:1860456
RefSeq - XM_006519632
RefSeq - NM_028994
RefSeq - XM_006519633
RefSeq Peptide - NP_083270
swissprot - Q8BH04
swissprot - A0A0R4J0G0
Ensembl - ENSMUSG00000040618
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PCK2ENSG00000100889Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pck1 / Q9Z2V4 / Phosphoenolpyruvate carboxykinase, cytosolic [GTP] / P35558* / phosphoenolpyruvate carboxykinase 1*ENSMUSG0000002751366


Protein motifs (from Interpro)
Interpro ID Name
 IPR008209  Phosphoenolpyruvate carboxykinase, GTP-utilising
 IPR008210  Phosphoenolpyruvate carboxykinase, N-terminal
 IPR013035  Phosphoenolpyruvate carboxykinase, C-terminal
 IPR018091  Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site
 IPR035077  Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal
 IPR035078  Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006090 pyruvate metabolic process IEA
 biological_processGO:0006094 gluconeogenesis IEA
 biological_processGO:0006107 oxaloacetate metabolic process IEA
 biological_processGO:0006116 NADH oxidation IEA
 biological_processGO:0032024 positive regulation of insulin secretion IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0071333 cellular response to glucose stimulus IEA
 biological_processGO:0071356 cellular response to tumor necrosis factor IEA
 biological_processGO:0071548 response to dexamethasone IEA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004611 phosphoenolpyruvate carboxykinase activity IEA
 molecular_functionGO:0004613 phosphoenolpyruvate carboxykinase (GTP) activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016831 carboxy-lyase activity IEA
 molecular_functionGO:0017076 purine nucleotide binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Gluconeogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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